Research Scientist Productivity and Firm Size: Evidence from Panel Data on Inventors

It has long been recognized that worker wages and possibly productivity are higher in large firms. Moreover, at least since Schumpeter (1942) economists have been interested in the relative efficiency of large firms in the research and development enterprise. This paper uses longitudinal worker-firm-matched data to examine the relationship between the productivity of workers specifically engaged in innovation and firm size in the pharmaceutical and semiconductor industries. In both industries, we find that inventors’ productivity increases with firm size. This result holds across different specifications and even after controlling for inventors’ experience, past productivity, the quality of other inventors in the firm, and other firm characteristicsPatents; Innovation; Labor productivity; Research; Firm size

Research Scientist Productivity and Firm Size: Evidence from Panel Data on Investors

It has long been recognized that worker wages and possibly productivity are higher in large firms. Moreover, at least since Schumpeter (1942) economists have been interested in the relative efficiency of large firms in the research and development enterprise. This paper uses longitudinal worker-firm-matched data to examine the relationship between the productivity of workers specifically engaged in innovation and firm size in the pharmaceutical and semiconductor industries. In both industries, we find that inventors' productivity increases with firm size. This result holds across different specifications and even after controlling for inventors' experience, education, the quality of other inventors in the firm, and other firm characteristics. We find evidence in the pharmaceutical industry that this is partly accounted for by differences between how large and small firms organize R&D activities.Patents; Innovation; Labor productivity; Research; Firm size

International Knowledge Flows: Evidence from an Inventor-Firm Matched Data Set

We describe the construction of a panel data set from the U.S. patent data that contains measures of inventors' life-cycle R&D productivity--patents and patent citations. We match the data set to information on the U.S. pharmaceutical and semiconductor firms for whom they work. In this paper we use these data to examine the role of research personnel as a pathway for the diffusion of ideas from foreign countries to U.S. innovators. In particular, we find in recent years an increase in the extent that U.S. innovating firms collaborate with or employ researchers with foreign experience. This increase appears to work primarily through an increase in U.S. firms' employment of foreign-residing researchers; the fraction of research-active U.S. residents with foreign research experience appears to be falling, suggesting that U.S. pharmaceutical and semiconductor firms are increasingly locating operations in foreign countries to employ such researchers, as opposed to such researchers immigrating to the U.S. to work. In addition, we investigate which U.S. firms conducting R&D build upon innovations originating abroad. We find that employing or collaborating with researchers who have research experience abroad seems to facilitate the use of output of non-U.S. R&D. We also find that in the semiconductor industry smaller and older firms, and in the pharmaceutical industry, younger firms are more likely to access foreign R&D output.

The Influence of University Research on Industrial Innovation

We use U.S. patent records to examine the role of research personnel as a pathway for the diffusion of ideas from university to industry. Appearing on a patent assigned to a university is evidence that an inventor has been exposed to university research, either directly as a university researcher or through some form of collaboration with university researchers. Having an advanced degree is another indicator of an inventor's exposure to university research. We find a steady increase in industry's use of inventors with university research experience over the period 1985-97, economy wide and in the pharmaceutical and semiconductor industries in particular. We interpret this as evidence of growth in the influence of university research on industrial innovation. Moreover, during this period we find that firms with large research operations in both industries, and young and highly capitalized firms in the pharmaceutical industry, are disproportionately active in the diffusion of ideas from the university sector. Finally, we find that the patents of firms that employ inventors with university research experience are more likely to cite university patents as prior art, suggesting that this experience better enables firms to tap academic research.

RADIO: Reference-Agnostic Dubbing Video Synthesis

One of the most challenging problems in audio-driven talking head generation is achieving high-fidelity detail while ensuring precise synchronization. Given only a single reference image, extracting meaningful identity attributes becomes even more challenging, often causing the network to mirror the facial and lip structures too closely. To address these issues, we introduce RADIO, a framework engineered to yield high-quality dubbed videos regardless of the pose or expression in reference images. The key is to modulate the decoder layers using latent space composed of audio and reference features. Additionally, we incorporate ViT blocks into the decoder to emphasize high-fidelity details, especially in the lip region. Our experimental results demonstrate that RADIO displays high synchronization without the loss of fidelity. Especially in harsh scenarios where the reference frame deviates significantly from the ground truth, our method outperforms state-of-the-art methods, highlighting its robustness. Pre-trained model and codes will be made public after the review.Comment: Under revie

Sericea lespedeza (Lespedeza cuneata) whole plant extract enhances rat muscle mass and sperm production by increasing the activity of NO-cGMP pathway and serum testosterone

Purpose: To analyze the effects of an aqueous extract of Sericea lespedeza (SL) on rat male menopause.Methods: Levels of nitric oxide (NO), endothelial nitric oxide synthase (NOS), cGMP, and prostaglandin E2 (PGE2) in the penile corpus cavernosum of the rats were evaluated using appropriate kits. Serum levels of dihydrotestosterone (DHT), testosterone, sex hormone-binding globulin (SHBG), and 17-beta hydroxysteroid dehydrogenases (17β-HSD) were measured with enzyme-linked immunosorbent assay kits. Total and motile sperms were counted on a hemocytometer. Histological changes in rat testis and epididymis were analyzed with hematoxylin and eosin staining.Results: The levels of NO, NOS, and cGMP (but not PGE2) increased in a dose-dependent manner (p< 0.05) upon administration of an aqueous extract of SL (AESL), while levels of DHT, 17β-HSD, and testosterone increased in the group administered with 300 mg/kg of AESL. Epididymal sperm count increased by 24 % in such rats compared to controls (p < 0.05).Conclusion: The aqueous extract of SL improves sperm count and muscle mass in rats by increasing the levels of NO, NOS, cGMP and testosterone. Thus, SL extract can potentially be developed as an alternative therapeutic agent for clinical management of TDS. Keywords: NO-cGMP, Testosterone, Hormones, Sperm count, Muscle mass, Sericea lespedeza, Lespedeza cuneat

Coupled CFD/CSD Analysis of a Hovering Rotor Using High Fidelity Unsteady Aerodynamics and a Geometrically Exact Rotor Blade Analysis

This paper presents a combination of a computational structural dynamics (CSD) and high fidelity unsteady computational fluid dynamics (CFD) analysis. Regarding a helicopter in hover, aerodynamic loads are computed from the three-dimensional Navier-Stokes solver in overlapped grids, and blade motions are obtained from the geometrically exact rotor beam analysis. To couple those analyses, a loose coupling method is adopted and the results are validated regarding a civil transport helicopter.This study was supported by the Korea Aerospace Research Institute under Korean Helicopter Program Dual-Use Component Development Project, which is further funded by the Korean Ministry of Knowledge and Economics. And this research has also been supported by the Institute of Advanced Aerospace Technology in Seoul National University, Korea