Test Platform Development of Vessel???s Power Management System Using Hardware- in-the-Loop-Simulation Technique

A PMS (Power Management System) controls vessel's power systems to improve the system efficiency and to protect a blackout condition. The PMS should be developed with considering the type and the capacity of the vessel???s power system. It is necessary to test the PMS functions developed for vessel???s safe operations under various sailing situations. Therefore, the function tests in cooperation with practical power systems are required in the PMS development. In this paper, a hardware-in-the-loop (HIL) simulator is developed for the purposes of the PMS function tests. The HIL simulator can be more cost-effective, more time-saved, easier to reproduce, and safer beyond the normal operating range than conventional off-line simulators, especially at early stages in development processes or during fault tests. Vessel's power system model is developed by using a MATLAB/SIMULINK software and by communicating between an OPAL-RT???s OP5600 simulator. The PMS uses a Modbus communication protocol implemented using LabVIEW software. Representative tests of the PMS functions are performed to verify the validity of the proposed HIL-based test platform

Spatiotemporal Stochastic Resonance in Fully Frustrated Josephson Ladders

We consider a Josephson-junction ladder in an external magnetic field with half flux quantum per plaquette. When driven by external currents, periodic in time and staggered in space, such a fully frustrated system is found to display spatiotemporal stochastic resonance under the influence of thermal noise. Such resonance behavior is investigated both numerically and analytically, which reveals significant effects of anisotropy and yields rich physics.Comment: 8 pages in two columns, 8 figures, to appear in Phys. Rev.

SOLiDzipper: A High Speed Encoding Method for the Next-Generation Sequencing Data

Background Next-generation sequencing (NGS) methods pose computational challenges of handling large volumes of data. Although cloud computing offers a potential solution to these challenges, transferring a large data set across the internet is the biggest obstacle, which may be overcome by efficient encoding methods. When encoding is used to facilitate data transfer to the cloud, the time factor is equally as important as the encoding efficiency. Moreover, to take advantage of parallel processing in cloud computing, a parallel technique to decode and split compressed data in the cloud is essential. Hence in this review, we present SOLiDzipper, a new encoding method for NGS data. Methods The basic strategy of SOLiDzipper is to divide and encode. NGS data files contain both the sequence and non-sequence information whose encoding efficiencies are different. In SOLiDzipper, encoded data are stored in binary data block that does not contain the characteristic information of a specific sequence platform, which means that data can be decoded according to a desired platform even in cases of Illumina, Solexa or Roche 454 data. Results The main calculation time using Crossbow was 173 minutes when 40 EC2 nodes were involved. In that case, an analysis preparation time of 464 minutes is required to encode data in the latest DNA compression method like G-SQZ and transmit it on a 183 Mbit/s bandwidth. However, it takes 194 minutes to encode and transmit data with SOLiDzipper under the same bandwidth conditions. These results indicate that the entire processing time can be reduced according to the encoding methods used, under the same network bandwidth conditions. Considering the limited network bandwidth, high-speed, high-efficiency encoding methods such as SOLiDzipper can make a significant contribution to higher productivity in labs seeking to take advantage of the cloud as an alternative to local computing. Availability http://szipper.dinfree.com . Academic/non-profit: Binary available for direct download at no cost. For-profit: Submit request for for-profit license from the web-site

Properties of Magnesia Composites According to Replacement Ratio of Perlite

Recently, passive and zero-energy construction has increased in Korea due to the government`s continuous application of budget-conscious policies for establishments. Accordingly, construction materials are being advanced, and the required performance standards for insulation materials are increasing. However, problems such as fire vulnerability and degradation of physical properties for organic and inorganic insulation materials are shown, so it is necessary to solve this problem. The objective of this research is to examine the properties of the composites by analyzing the flexural breaking load, impact resistance, density, VOCs concentration reduction rate, and fine dust concentration reduction rate of the composites manufactured based on the perlite substitution rate of the magnesia composites. The flexural breaking load test of the composites was assessed according to ‘KS F 3504’, a gypsum board standard and the impact resistance was assessed according to ‘KS F 4715’. The performance evaluation of adsorption performance of air pollutants of the VOCs and fine dust in the context of the small chamber technique suggested by Hanbat University. The results of this study are as follows: The flexural breaking load according to the perlite replacement rate tended to decrease as the perlite replacement rate increased. It is determined that the flexural breaking load is reduced by generating a large amount of pores inside due to the perlite porous structure characteristics. In the case of impact resistance, the impact resistance tended to increase as the perlite displacement rate increased. It is determined that the volume of the binder in the board is reduced, and pores inside the board are generated due to perlite, which is a porous material, thereby reducing the overall bonding force of the board. In the case of VOCs and fine dust concentrations, the VOCs and fine dust concentration reduction rates tended to increase as the perlite replacement rate increased. In the case of the perlite displace rate of 30%, the VOCs concentration decreased by 82.6%, and the fine dust concentration decreased by 87.9%. It has been established that the porous properties of perlite used to create a huge number of pores in the hardened body cause the concentration to be lowered physically through adsorption. This study\u27s findings are thought to be fundamental information for securing the engineering properties and air pollution absorption of magnesia composites blended with perlite

A case of nearly complete response in hepatocellular carcinoma with disseminated lung metastasis by combination therapy of nivolumab and ipilimumab after treatment failure of atezolizumab plus bevacizumab

Recently, the efficacy of immuno-oncologic agents for advanced hepatocellular carcinoma (HCC) has been proven in several trials. In particular, atezolizumab with bevacizumab (AteBeva), as a first-line therapy for advanced HCC, has shown tremendous advances in the IMBrave150 study. However, second or third-line therapy after treatment failure with AteBeva has not been firmly established. Moreover, clinicians have continued their attempts at multidisciplinary treatment that includes other systemic therapy and radiotherapy (RT). Here, we report a case that showed a near complete response (CR) of lung metastasis to nivolumab with ipilimumab therapy after achieving a near CR of intrahepatic tumor using sorafenib and RT in a patient with advanced HCC who had experienced treatment failure of AteBeva