Favoriser l’insertion professionnelle et l’accès à l’emploi

Cherchant à adapter leurs services à l’actualité sociale et aux besoins réels de leur public, de plus en plus de bibliothèques se préoccupent d’offrir des services orientés vers l’insertion professionnelle et la recherche d’emploi. Qu’elle soit universitaire ou publique, la bibliothèque constitue une ressource essentielle de la formation tout au long de la vie, élément primordial à l’adaptation permanente au monde du travail. Cet ouvrage aborde cette nouvelle problématique pour les établissements sous trois angles différents, selon les besoins des publics : travailler, se former, entreprendre. Les conditions d’accueil des publics concernés, l’adaptation de l’offre suivant la dimension de la bibliothèque, la constitution des collections spécialisées dans ce domaine, la qualité des propositions en matière d’autoformation, les atouts des différents partenariats dans le domaine de la recherche d’emploi, tels sont les éléments traités ici pour favoriser le succès de la mise en place et du développement d’une offre propre à élargir avec efficacité les champs d’intervention des bibliothèques aujourd’hui. Coordonné par Georges Perrin, inspecteur général honoraire des bibliothèques, ce volume collectif réunit des professionnels spécialisés dans le domaine éducatif, social et culturel

Impact of selective reporting of antibiotic susceptibility test results on the appropriateness of antibiotics chosen by French general practitioners in urinary tract infections: a randomised controlled case-vignette study

International audienc

Probiotics and Intestinal Colonization by Vancomycin-Resistant Enterococci in Mice and Humans▿

We investigated the impact of probiotics on the intestinal carriage of vancomycin-resistant enterococci (VRE). Administration of Lactobacillus rhamnosus Lcr35 but not Escherichia coli Nissle reduced, although not significantly, the density of VRE colonization in a murine model. No effect of Lcr35 was observed in a double-blind placebo randomized study, involving nine patients

Fatal Cowpox Virus Infection in Human Fetus, France, 2017

International audienc

Is total community viral load a robust predictive marker of the efficacy of the TasP strategy?

International audienceA mild but significant association between a decrease in the total community viral load (CVL) and a decrease in the number of new HIV diagnoses was observed between 2005 and 2010 in the population of northern and eastern France. This result suggests that CVL could be used as robust marker of the efficacy of the "Treatment as Prevention" strategy, and it may even be stronger if a large number of undiagnosed patients and early HIV infection cases indicated by extend screening are included in the CVL measurement

Cancer-Related Causes of Death among HIV-Infected Patients in France in 2010: Evolution since 2000

the ARNS EN20 Mortalité 2010 study groupInternational audienceObjectivesThe current study aimed at describing the distribution and characteristics of malignancy related deaths in human immunodeficiency virus (HIV) infected patients in 2010 and at comparing them to those obtained in 2000 and 2005.MethodsData were obtained from three national surveys conducted in France in 2010, 2005 and 2000. The underlying cause of death was documented using a standardized questionnaire fulfilled in French hospital wards involved in the management of HIV infection.ResultsAmong the 728 deaths reported in 2010, 262 were cancer-related (36%). After a significant increase from 28% in 2000 to 33% in 2005 and 36% in 2010, cancers represent the leading cause of mortality in HIV infected patients. The proportion of deaths attributed to non-AIDS/non-hepatitis-related cancers significantly increased from 2000 to 2010 (11% of the deaths in 2000, 17% in 2005 and 22% in 2010, p<0.001), while those attributed to AIDS-defining cancers decreased during the same period (16% in 2000, 13% in 2005 and 9% in 2010, p = 0.024). Particularly, the proportion of respiratory cancers significantly increased from 5% in 2000 to 6% in 2005 and 11% in 2010 (p = 0.004). Lung cancer was the most common cancer-related cause of death in 2010 (instead of non-Hodgkin lymphoma so far) and represented the leading cause of death in people living with HIV overall.ConclusionsCancer prevention (especially smoking cessation), screening strategies and therapeutic management need to be optimized in HIV-infected patients in order to reduce mortality, particularly in the field of respiratory cancers

Patients' characteristics, by underlying cause of death–Mortalité 2010 survey, France.

<p>^aexcluding primary brain lymphoma</p><p>^blast measure of CD4 or HIV-RNA before death</p><p>^c more than 30 grams/day</p><p>^dcurrent or past consumption</p><p>IQR: interquartile range; HIV: human immunodeficiency virus; AIDS: acquired immunodeficiency syndrome; ARV: antiretroviral</p><p>Patients' characteristics, by underlying cause of death–Mortalité 2010 survey, France.</p

Cancer-related causes of death.

<p>The Mortalité 2000, Mortalité 2005 and Mortalité 2010 surveys, France.</p><p>^aComparisons between 2000, 2005 and 2010 adjusted on age and gender</p><p>^bincluding 3 patients with both non Hodgkin lymphoma and Kaposi sarcoma</p><p>^cSee Appendix for details</p><p>^dMultiple: anus+prostate, anus+lung, lung+breast</p><p>Cancer-related causes of death.</p

Persistent headaches one year after bacterial meningitis: prevalence, determinants and impact on quality of life

International audienceBackground: Little is known on headaches long-term persistence after bacterial meningitis and on their impact on patients' quality of life.Methods: In an ancillary study of the French national prospective cohort of community-acquired bacterial meningitis in adults (COMBAT) conducted between February 2013 and July 2015, we collected self-reported headaches before, at onset, and 12 months (M12) after meningitis. Determinants of persistent headache (PH) at M12, their association with M12 quality of life (SF 12), depression (Center for Epidemiologic Studies Depression Scale) and neuro-functional disability were analysed.Results: Among the 277 alive patients at M12 87/274 (31.8%), 213/271 (78.6%) and 86/277 (31.0%) reported headaches before, at the onset, and at M12, respectively. In multivariate analysis, female sex (OR: 2.75 [1.54-4.90]; p < 0.001), pre-existing headaches before meningitis (OR: 2.38 [1.32-4.30]; p < 0.01), higher neutrophilic polynuclei percentage in the CSF of the initial lumbar puncture (OR: 1.02 [1.00-1.04]; p < 0.05), and brain abscess during the initial hospitalisation (OR: 8.32 [1.97-35.16]; p < 0.01) were associated with M12 persistent headaches. Neither the responsible microorganism, nor the corticoids use were associated with M12 persistent headaches. M12 neuro-functional disability (altered Glasgow Outcome Scale; p < 0.01), M12 physical handicap (altered modified Rankin score; p < 0.001), M12 depressive symptoms (p < 0.0001), and M12 altered physical (p < 0.05) and mental (p < 0.0001) qualities of life were associated with M12 headaches.Conclusion: Persistent headaches are frequent one year after meningitis and are associated with quality of life alteration