Trastornos mentales y del comportamiento derivados de la atención o infección de COVID-19 en profesionales de la salud: Estudio de casos en una institución pública

Introducción: Este estudio investiga el impacto psicológico y psiquiátrico de la COVID-19 en profesionales de la salud. Se centra en cómo la pandemia, a través del estrés laboral y la exposición directa al virus, ha incrementado los casos de ansiedad, depresión y TEPT entre estos trabajadores, particularmente en México. Se analizan datos comparativos globales para contextualizar la magnitud del problema a nivel internacional. Objetivo: Analizar las consecuencias derivadas de los trastornos mentales y del comportamiento por COVID-19 en los profesionales de la salud de una Institución Pública de una entidad federativa en  México Métodos: Estudio observacional, transversal y retrospectivo, en el periodo 2020-2023. Se seleccionaron 58 casos de trastornos mentales vinculados al trabajo en condiciones de COVID-19, con especial atención en 19 casos directamente asociados a la enfermedad. Resultados: un 57.9% de los profesionales de la salud afectados por COVID-19 eran mujeres, principalmente de 40-50 años. El  94.7%, trabajaba en seguridad social, con médicos y enfermeros como las ocupaciones más comunes. Los trastornos mentales estudiados estuvieron fuertemente influenciados por factores biológicos, y la difucltad en la concentración y la ansiedad se perfilaron como el síntoma predominante. El análisis destacó que la gravedad de la COVID-19 y la severidad de trastornos como la depresión mayor. Las incapacidades laborales reflejaron una tendencia alarmante hacia periodos extensos de ausencia. Estos hallazgos subrayan la carga económica y humana del COVID-19 en el sector salud. Conclusiones: Se destaca la urgencia de estrategias de apoyo psicológico para el personal sanitario y la importancia de integrar la salud mental en la formación y políticas de salud ocupacional. La investigación resalta la necesidad de una vigilancia continua en salud mental y la realización de estudios longitudinales futuro

Antiphospholipid Antibodies and Lipids in Hematological Malignancies

One of the main groups of lipids is phospholipids, which are mainly involved in forming cell membranes. Neoplastic processes such as cell replication have increased lipid synthesis, making tumor cells dependent on this synthesis to maintain their requirements. Antiphospholipid antibodies attack phospholipids in the cell membranes. Three main types of antiphospholipid antibodies are recognized: anti-β2 glycoprotein I (anti-β2GP-I), anticardiolipin (aCL), and lupus anticoagulant (LA). These types of antibodies have been proven to be present in hematological neoplasms, particularly in LH and NHL. This review on antiphospholipid antibodies in hematological neoplasms describes their clinical relationship as future implications at the prognostic level for survival and even treatment

The Hypertriglyceridemic Waist Phenotype Is Associated with Several Cardiovascular Risk Factors in Women with Rheumatoid Arthritis

Rheumatoid arthritis (RA) associates with cardiovascular risk factors (CVRF) such as dyslipidemias and systemic inflammation. Cardiovascular Disease (CVD) is the leading cause of mortality. The hypertriglyceridemic waist phenotype (HTWP) identifies increased CVRF; however, information about HTWP on RA is scarce. Objective: To evaluate the association of HTWP with CVRF in RA. Material and methods: Cross-sectional study. Women (125) with RA were included (ACR, 1987). Anthropometry, bioimpedance, body mass index (BMI), disease activity score 28 (DAS28), and health assessment questionnaire disability index (HAQ-Di) were determined. The lipid profile determination includes the atherogenic index (AI) (TC/HDL) and Framingham Risk Score. HTWP is defined as a waist circumference ≥88 cm and triglycerides ≥ 150 mg/dL. Chi-squared and Student’s t-tests were applied for comparisons. Results: HTWP was found in 38 (30.4%) patients. The subgroup with HTWP had a greater frequency of arterial hypertension (AHT) (57.9 vs. 37.9, p = 0.04), Type 2 DM (23.7 vs. 8.0, p= 0.02), BMI (29.7 ± 3.2, vs. 26.8 ± 4.3, p < 0.001), fat mass (39.3 ± 4.8 vs. 34.7 ± 6.8, p < 0.001), and AI (4.7 ± 1.2 vs. 3.7 ± 1.0, p < 0.001). No differences between DAS28 and HAQ-Di were found. HTWP was associated with the presence of MetS and CVR (p < 0.001 and p = 0.012, respectively). Conclusion: The HTWP in RA is associated with CVRF, and its potential predictive role should be evaluated in longitudinal studies

The Hypertriglyceridemic Waist Phenotype Is Associated with Several Cardiovascular Risk Factors in Women with Rheumatoid Arthritis

Rheumatoid arthritis (RA) associates with cardiovascular risk factors (CVRF) such as dyslipidemias and systemic inflammation. Cardiovascular Disease (CVD) is the leading cause of mortality. The hypertriglyceridemic waist phenotype (HTWP) identifies increased CVRF; however, information about HTWP on RA is scarce. Objective: To evaluate the association of HTWP with CVRF in RA. Material and methods: Cross-sectional study. Women (125) with RA were included (ACR, 1987). Anthropometry, bioimpedance, body mass index (BMI), disease activity score 28 (DAS28), and health assessment questionnaire disability index (HAQ-Di) were determined. The lipid profile determination includes the atherogenic index (AI) (TC/HDL) and Framingham Risk Score. HTWP is defined as a waist circumference ≥88 cm and triglycerides ≥ 150 mg/dL. Chi-squared and Student’s t-tests were applied for comparisons. Results: HTWP was found in 38 (30.4%) patients. The subgroup with HTWP had a greater frequency of arterial hypertension (AHT) (57.9 vs. 37.9, p = 0.04), Type 2 DM (23.7 vs. 8.0, p= 0.02), BMI (29.7 ± 3.2, vs. 26.8 ± 4.3, p p p p p = 0.012, respectively). Conclusion: The HTWP in RA is associated with CVRF, and its potential predictive role should be evaluated in longitudinal studies