Assessment of stress & related albuminuria in caregivers of severe mentally ill persons

Background & objectives: The family caregivers of patients with chronic diseases are known to undergo psychiatric stress leading to oxidative damage to glomerular membrane of kidney resulting in proteinuria. This study was aimed to compare current anxiety, depression levels and urinary albumin:creatinine ratio between primary caregivers of chronic mental patients and matched controls, and also whether the urinary albumin : creatinine ratio is correlated with stress factors (state and trait anxiety level, depression and caregiver burden) amongst caregivers. Methods: The present cross-sectional study included 131 subjects (93 primary caregivers of patients with major mental illness as cases and 38 normal controls). They completed the Burden Assessment Schedule of SCARF, State Trait Anxiety Inventory and Beck′s Depression Inventory. A spot urine sample was tested for urinary albumin : creatinine ratio from all study subjects. Results: Mean values of current State and Trait anxiety, depression, urinary albumin:creatinine ratio were significantly higher in caregivers than controls (P < 0.001). Urinary albumin : creatinine ratio was significantly correlated (P < 0.001) with State and Trait anxiety level, depression as well as caregiver burden. Interpretation & conclusions: The study demonstrated depression , anxiety and albuminuria amongst primary caregivers of patients with mental illness. Increase in the caregivers′ burden, depression and anxiety resulted in an increase in the urinary albumin: creatinine ratio. This indicates that psychological stress is one of the determinants of albumin excretion rate in otherwise healthy subjects

Low strain rate compressive failure mechanism of coarse grain alumina

The present work reports the dynamic compressive strength (sigma(c)) of a dense (similar to 95%) coarse grain (similar to 20 mu m) alumina measured at 30 degrees C as a function of strain rates ((epsilon) over dot) ranging from 10(-5) to 5 x 10(-1) s(-1). The results showed a unique 40% enhancement of (sigma(c)) with the increase in ((epsilon) over dot). Extensive post mortem examination of fracture fragments obtained from the compressive failure tests by FESEM, TEM and HRTEM confirmed the formation of micro-cracks, shear bands, nanoscale cleavages and dislocations whose recurrence had increased with strain rate. Both shear induced microplasticity and nanoscale cleavages as well as dislocations had occurred concurrently yet independently during compressive fracture of coarse grain alumina even at very low strain rates. Based on these evidences a new compressive failure mechanism of alumina was proposed. (C) 2016 Elsevier Ltd and Techna Group S.r.l. All rights reserved

Book of Abstracts of the 2nd International Conference on Applied Mathematics and Computational Sciences (ICAMCS-2022)

It is a great privilege for us to present the abstract book of ICAMCS-2022 to the authors and the delegates of the event. We hope that you will find it useful, valuable, aspiring, and inspiring. This book is a record of abstracts of the keynote talks, invited talks, and papers presented by the participants, which indicates the progress and state of development in research at the time of writing the research article. It is an invaluable asset to all researchers. The book provides a permanent record of this asset. Conference Title: 2nd International Conference on Applied Mathematics and Computational SciencesConference Acronym: ICAMCS-2022Conference Date: 12-14 October 2022Conference Organizers: DIT University, Dehradun, IndiaConference Mode: Online (Virtual