Modeling quasi-static magnetohydrodynamic turbulence with variable energy flux

In quasi-static MHD, experiments and numerical simulations reveal that the energy spectrum is steeper than Kolmogorov's $k^{-5/3}$ spectrum. To explain this observation, we construct turbulence models based on variable energy flux, which is caused by the Joule dissipation. In the first model, which is applicable to small interaction parameters, the energy spectrum is a power law, but with a spectral exponent steeper than -5/3. In the other limit of large interaction parameters, the second model predicts an exponential energy spectrum and flux. The model predictions are in good agreement with the numerical results.Comment: 16 pages, 5 figure

Self-assembly and potassium ion triggered disruption of peptide-based soft structures

This report describes formation of soft vesicular structures by a tetrapeptide and its disruption triggered by potassium ions

Simulation of rapid loading systems in iron ore mines

In the mining industry, it is observed that sudden break-down of any equipment may stop the entire system, resulting in drastic production losses and enhancing the cost production. In this paper, the probability of sudden break down of each equipment are individually analyzed from their previous performances where the frequency of occurrences, duration and the time-interval of each breakdown has given an additional stress and the non-availability of that equipment on the entire system is discussed. Computerized best fit matching is found out for preventive maintenance of this equipment by developing different sub-routines and simulation models. Optimum utilization of those equipment shows a particular steady- state production from the mine. Advanced technology is used for the operation of the open-pit mining. Hazard due to open cast mining is less than that of underground mines and the recent trend is to adopt the former one. For the mechanization, different types of machineries are used, such as shovel, dumper, dozer, drill machines, etc. use of more machineries increases the complexity of the operation and as a result it is very difficult to the proper matching of these equipment’s. As these machineries are very costly so unless they are properly matched, reduction in production cost is not possible. Sudden breakdown of one equipment may stop the production from whole mine. So it is needed to analyze the breakdown data by statistical approach to find out the possibility of breakdown of that particular equipment and ask for preventive maintenance. This analysis needed the help of computer for simulating the whole mining system to judge the performance of each equipment. This paper deals with the computerized best fit matching, for preventive maintenance of equipment

N7-(carboxymethyl)guanine-lithium crystalline complex: a bioinspired solid electrolyte

Electrochemical device with components having direct significance to biological life processes is a potent futuristic strategy for the realization of all-round green and sustainable development. We present here synthesis design, structural analysis and ion transport of a novel solid organic electrolyte (G7Li), a compound reminiscent of ion channels, derived from regioisomeric N7-guanine-carboxylate conjugate and Li-ions. G7Li, with it\u27s in-built supply of Li(+)-ions, exhibited remarkably high lithium-ion transference number (= 0.75) and tunable room temperature ionic conductivity spanning three decades (≈10(-7) to 10(-3) Ω(-1) cm(-1)) as a function of moisture content. The ionic conductivity show a distinct reversible transition around 80-100 °C, from a dual Li(+) and H(+) (<100 °C) to a pure Li(+) conductor (>100 °C). Systematic studies reveal a transition from water-assisted Li-ion transport to Li hopping-like mechanism involving guanine-Li coordination. While as-synthesized G7Li has potential in humidity sensors, the anhydrous G7Li is attractive for rechargeable batteries

Development of a rapid loop-mediated isothermal amplification assay for diagnosis and assessment of cure of Leishmania infection

BACKGROUND: Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A robust, rapid and cost effective diagnostic test is warranted for on-time diagnosis and field application. METHODS: We have developed a loop mediated isothermal amplification (LAMP) assay with primers (n = 6) based on Leishmania donovani kDNA for detection of Leishmania infection, using a closed tube to prevent cross-contamination. The assay was used to detect Leishmania infection in biological samples obtained from patients of visceral leishmaniasis (VL), post kala-azar dermal leishmaniasis (PKDL) and cutaneous leishmaniasis (CL). RESULTS: The assay was positive for L. donovani, L. tropica and L. major parasites, with the highest sensitivity towards L. donovani (1 fg DNA). The high sensitivity of the assay for detection of L. donovani was reflected in its ability to detect parasite DNA within 30 min of amplification time with a threshold detection limit of ≥25 copies per reaction. The assay detected parasite in 64 of 66 VL blood samples (sensitivity, 96.9%; 95% CI: 89.6-99.2%), 15 of 15 VL bone marrow aspirate samples (sensitivity, 100%; 95% CI:79.6-100%), 65 of 67 PKDL tissue biopsy samples (sensitivity, 97%; 95% CI:89.7-99.2%). The assay was evaluated in a few cases of CL wherein it was found positive in 8 of 10 tissue biopsies (sensitivity, 80%; 95% CI: 49-94.3%). The assay was negative in all control blood (n = 76) and tissue biopsy (n = 24) samples (specificity, 100%; 95% CI: 96.3-100%). Further, the assay was evaluated for its utility in assessment of cure in treated VL and PKDL patients. The assay detected parasite DNA in 2 of 20VL blood samples and 2 of 21 PKDL tissue samples. Out of 4 cases that were positive for parasite DNA at post treatment stage, 2 patients (1VL and 1 PKDL) returned with relapse. CONCLUSIONS: The study demonstrated a Leishmania genus specific closed tube LAMP assay for reliable and rapid molecular diagnosis of VL and PKDL with potential for application in assessment of cure

Development of 3D Angle-Interlock Woven Preforms for Composites

The advent of three dimensional (3D) reinforcements has been mainly to overcome the issue of delamination and improve upon the damage tolerance properties by introducing fibres in the thickness direction for advanced composite applications. 3D preforms can be developed using various techniques. Angle-interlock weaving is one of them. This paper details about the efforts being put at CSIR-NAL for developing angle-interlock woven preforms. Four types of angle-interlock structures viz., layer-to-layer and through thickness (both with and without stuffer yarns) were developed using 6K, 400 Tex TC-33 grade Carbon tows on a custom designed handloom. The preforms without stuffer yarns had 4 layers of warp and were of 1.5± 0.2 mm thick. Preforms with stuffer yarns had 6 layers of warp (including 2 stuffer yarn layers) and were of 2.3±0.1 mm thick. Thermoset composites were prepared from these preforms using EPOLAM 2063 (an epoxy based resin system) by RTM process. The fibre weight fraction for these composites ranged from 0.53 to 0.58 and they were subjected to mechanical tests such as tensile, flexural and interlaminar shear strength. Test results showed improved response (in the warp direction) with respect to shear properties while the tensile and flexural properties were equivalent to that of the plain woven composites