53,673 research outputs found

    What else can the world’s billionaires do?

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    Together, 2,000 billionaires hold US$9 trillion in wealth, but only 78 are taking significant action against the Covid-19 crisis, writes Sandeep Sachdev

    Alumni Highlight: Sandeep Chadha

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    Sandeep Chadha is a Partner at Milestone Capital Advisors (AUM $800 million) and has 14-plus years of experience in fund raising, investments, asset management and divestments. As a part of senior management at Milestone, he oversees the private REIT portfolio including investments and asset management. Sandeep is responsible for setting up a domestic private REIT focused on investments in commercial assets. His past assignments include managing 25 million square feet of commercial real estate for Unitech and asset management of assets for Everstone Capital and IL&FS Milestone Realty

    Canadian Women Army Corps

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    Public history poster on Canada’s military past about the Canadian Women Army Corps by students Sandeep Barring, Nadine Joseph, and Linda Dao.https://source.sheridancollege.ca/swfhass_military_posters/1004/thumbnail.jp

    On a version of Trudinger-Moser inequality with M\"obius shift invariance

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    The paper raises a question about the optimal critical nonlinearity for the Sobolev space in two dimensions, connected to loss of compactness, and discusses the pertinent concentration compactness framework. We study properties of the improved version of the Trudinger-Moser inequality on the open unit disk B⊂R2B\subset\R^2, recently proved by G. Mancini and K. Sandeep. Unlike the original Trudinger-Moser inequality, this inequality is invariant with respect to M\"obius automorphisms of the unit disk, and as such is a closer analogy of the critical nonlinearity ∫∣u∣2∗\int |u|^{2^*} in the higher dimension than the original Trudinger-Moser nonlinearity.Comment: This version gives the credit to an independently proved result, missed in the early version, and corrects an error in one of the proof

    Diastolic And Systolic Right Ventricular Dysfunction Precedes Left Ventricular Dysfunction In Patients Paced From Right Ventricular Apex

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    Background: Cardiac dysfunction after right ventricular (RV) apical pacing is well known but its extent, time frame of appearance and individual effect on left ventricular (LV), RV systolic and diastolic parameters has not evaluated in a systematic fashion. Methods: Patients with symptomatic bradycardia and ACC-AHA Class I indication for permanent pacemaker implantation (PPI) were implanted a single chamber (VVI) pacemaker. They were followed prospectively by echocardiographic examination which was done at baseline, 1 week, 1 month and 6 months after implantation. Parameters observed were chamber dimensions (M-line), chamber volumes, cardiac output (modified Simpson's method), systolic functions (ejection fraction, pre-ejection period, ejection time and ratio) and diastolic functions( isovolumic relaxation time & deceleration time) of left and right heart. Results: Forty eight consecutive patients (mean age 65.6±11.8 yrs, 66.7% males, mean EF 61.82±10.36%) implanted a VVI pacemaker were enrolled in this study. The first significant change to appear in cardiac function after VVI pacing was in diastolic properties of RV as shown by increase in RV isovolumic relaxation time (IVRT) from 65.89±15.93 to 76.58±17.00 ms,(p<0.001) at 1week and RV deceleration time (DT) from 133.84±38.13 to 153.09±31.41 ms, (p=0.02) at 1 month. Increase in RV internal dimension (RVID) from 1.26±0.41 to 1.44±0.44, (p<0.05) was also noticed at 1 week. The LV diastolic parameters were significantly altered after 1 month with increase in LV-IVRT from 92.36±21.47 to 117.24±27.21ms, (p<0.001) and increase in LV DT from 147.56±31.84 to 189.27±28.49ms,(p<0.01). This was followed by LV systolic abnormality which appeared at 6 months with an increase in LVPEP from 100.33±14.43 to 118.41±21.34ms, (p<0.001) and increase in LVPEP/LVET ratio from 0.34±0.46 to 0.44±0.10, (p<0.001)]. The reduction in LV EF was manifested at 6 months falling from 61.82±10.36% to52.52±12.11%, (p<0.05) without any significant change in the resting cardiac output. Conclusion: The present study shows that dysfunction of right ventricle is the first abnormality that occurs in VVI paced patients, which manifests by 1 week followed by LV dysfunction which starts appearing by 1 month and the diastolic dysfunctions precede the systolic dysfunction in both ventricles
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