1,594 research outputs found
An analysis on the feasibility of supporting and funding rural education through private education in Argentina
Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p. 56-58).The quality of education in Argentina has been declining over the past decades, affecting specially rural and marginalized sectors of the population. Given the current circumstances, in which the government has increased the amount of the GDP invested in education, and there is still no concrete evidence that the quality of the education is improving, the objective of this thesis is to find alternatives to solve this problem through a private and self-sustainable initiative in which private education can cross-collaborate and fund rural or marginalized schools in Argentina. My research will focus on determining whether it is feasible to establish a sustainable model of collaboration, and determining which is the most impactful way to establish it. The aim of this thesis is to examine the effectiveness of a sustainable self-funding model, which partners elite and rural/marginalized schools. This cooperation model should help students from impoverished backgrounds to achieve higher education performance, enabling them to succeed in having access to a better quality of life, and hopefully will result in a more fair and inclusive society.by Nora Sanchez Brion.M.B.A
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Analytical and sensory evaluation of hop varieties
The German hop Hallertauer, hallertauer is highly
valued because of its "noble aroma", but it has a very low
yield when cultivated in the U.S. Two new crosses of
Hallertauer, U.S.D.A. 21455 and 21459, have high yields
and promising aroma characteristics.
In order to predict sensory properties of beers as a
function of the varieties of hop used in brewing, a more
complete sensory and chemical characterization of hop oils
is necessary.
The aims of this study were to compare the aroma
profiles of the new crosses against the German variety by
determining their most important odor active compounds,
and correlating the sensory attributes evaluated by a
descriptive sensory panel (DSP) with the odor intensities
detected during the gas chromatograph (GC) effluent detected during the gas chromatograph (GC) effluent
sniffing. Oxygenated fractions were spiked into spring
water and evaluated by the DSP. The same samples were
injected into the GC and the effluents were evaluated
quantitatively and qualitatively by four subjects using a
special data collection device. Samples were then analyzed
by mass spectrometry (MS). There were no significant
differences among the three varieties based upon the DSP
results and the "aromagrams" obtained during the sniffing
of the GC effluents. Important odor active peaks were
associated with humulene oxidation products. A number of
statistical correlations existed between the sensory
attributes and the odor active peaks. In summary, the new
varieties are potential contributors to "noble aroma".
Trials with beers brewed with these hops are underway in
order to establish their contribution to beer flavor
Is there a link between the divorce revolution and the cohabitation boom?
Over the past decades, divorce and cohabitation have increased dramatically throughout Europe. Divorce has fundamentally altered the institution of marriage from a life-long union to one that may dissolve. Cohabitation allows couples to live together without undertaking the vows of marriage, but also allows couples to avoid the potentially higher costs of divorce. Thus, divorce and cohabitation seem to be intrinsically linked. Here we theorize how the increase in divorce may be linked to the increase in cohabitation on the macro-, meso-, and micro- levels. Using focus group data from 8 countries, we explore how divorce may have changed attitudes and beliefs concerning marriage and cohabitation. We then investigate whether survey data and official statistics in 16 countries provide evidence consistent with a link. While exogenous factors have been important for the increase in cohabitation, we argue that the divorce revolution has been a catalyst for the cohabitation boom
Aplicación del sistema de gestión de almacén y la mejora de la calidad de servicio que brinda el personal administrativo de una universidad Nacional de Trujillo, año 2022
La presente investigación titulada Aplicación del Sistema de Gestión
de Almacén y la mejora de la Calidad de servicio que brinda el personal administrativo
de una Facultad en una Universidad de Trujillo, año 2022.” Tuvo como objetivo
principal establecer la relación que existe entre la Gestión de almacén y calidad de
servicio de los servidores de la facultad de Ciencias Físicas y Matemáticas.
La investigación fue de tipo básica, diseño no experimental, transversal y
correlacional, cuya población estuvo conformada por los servidores administrativos
en la gestión de almacenes lo cual comprende 27 trabajadores, la muestra estuvo con
formada por 27 servidores administrativos, para la recolección de datos se aplicó la
técnica de la encuesta y el cuestionario como instrumento los cuales fueron validades
por juicios expertos y determinaron su confiabilidad mediante el instrumento estadístico del alfa de Cronbach.
Los resultados establecieron que la gestión de Almacén según la percepción
de los servidores administrativos muestra un nivel moderado
Análisis de la metodología aula invertida en enseñanza de posgrado en una Institución de Educación Superior de Paraguay
The main objective of this research work was to analyze the acceptance and valuation of the method called "Inverted Classroom by Nora Ruoti", as a learning approach in graduate education by students of the Master's Degree in Taxation of the second semester of 2019 of the FOTRIEM Faculty of the Republic of Paraguay. A quantitative approach methodology was used, descriptive design, non-experimental, the data collection instrument was the questionnaire through the Google form. The data were collected longitudinally from the students. The sample of the study was 114 participants. The results obtained showed that the deep learning approach, with active participation, encouraged through the inverted classroom method, even when it requires greater investment of time and dedication of various actors of the educational community, are highly satisfactory in the performance of graduate level students. It is recommended to other researchers to deepen the subject of studies with the use of audio books for the inverted classroomEl presente trabajo de investigación tuvo por objetivo principal analizar la aceptación y valoración del método denominado “Aula invertida by Nora Ruoti”, como enfoque de aprendizaje en la educación de posgrado por parte de los estudiantes de la maestría en impuestos del segundo semestre del año 2019 de la Facultad FOTRIEM de la República del Paraguay. Se utilizó una metodología de enfoque cuantitativo, de diseño descriptivo, no experimental, el instrumento de recolección de datos fue el cuestionario a través del formulario de Google. Los datos se recogieron de manera longitudinal a los estudiantes. La muestra del estudio fue de 114 participantes. Los resultados obtenidos demostraron que el enfoque de aprendizaje profundo, con participación activa, incentivada mediante el método de aula invertida, aun cuando requiera mayor inversión de tiempo y dedicación de diversos actores de la comunidad educativa, son altamente satisfactorios en el rendimiento de los estudiantes de nivel de postgrado. Se recomienda a otros investigadores profundizar el tema de estudios con el uso de audio libros para el aula invertida
Análisis de la metodología aula invertida en enseñanza de posgrado en una Institución de Educación Superior de Paraguay
The main objective of this research work was to analyze the acceptance and valuation of the method called "Inverted Classroom by Nora Ruoti", as a learning approach in graduate education by students of the Master's Degree in Taxation of the second semester of 2019 of the FOTRIEM Faculty of the Republic of Paraguay. A quantitative approach methodology was used, descriptive design, non-experimental, the data collection instrument was the questionnaire through the Google form. The data were collected longitudinally from the students. The sample of the study was 114 participants. The results obtained showed that the deep learning approach, with active participation, encouraged through the inverted classroom method, even when it requires greater investment of time and dedication of various actors of the educational community, are highly satisfactory in the performance of graduate level students. It is recommended to other researchers to deepen the subject of studies with the use of audio books for the inverted classroom.El presente trabajo de investigación tuvo por objetivo principal analizar la aceptación y valoración del método denominado “Aula invertida by Nora Ruoti”, como enfoque de aprendizaje en la educación de posgrado por parte de los estudiantes de la maestría en impuestos del segundo semestre del año 2019 de la Facultad FOTRIEM de la República del Paraguay. Se utilizó una metodología de enfoque cuantitativo, de diseño descriptivo, no experimental, el instrumento de recolección de datos fue el cuestionario a través del formulario de Google. Los datos se recogieron de manera longitudinal a los estudiantes. La muestra del estudio fue de 114 participantes. Los resultados obtenidos demostraron que el enfoque de aprendizaje profundo, con participación activa, incentivada mediante el método de aula invertida, aun cuando requiera mayor inversión de tiempo y dedicación de diversos actores de la comunidad educativa, son altamente satisfactorios en el rendimiento de los estudiantes de nivel de postgrado. Se recomienda a otros investigadores profundizar el tema de estudios con el uso de audio libros para el aula invertida
Enhancement of Th1 immune responses to recombinant influenza nucleoprotein by Ribi adjuvant
A broad coverage influenza vaccine against multiple viral strains based on the viral nucleoprotein (NP) is a goal pursued by many laboratories. If the goal is to formulate the vaccine with recombinant NP it is essential to count on adjuvants capable of inducing cellular immunity. This work have studied the effect of the monophosphoryl lipid A and trehalose dimycolate, known as the Ribi Adjuvant System (RAS), in the immune response induced in mice immunized with recombinant NP. The NP was formulated with RAS and used to immunize BALB/c mice. Immunizations with NP-RAS increased the humoral and cellular immune responses compared to unadjuvanted NP. The predominant antibody isotype was IgG2a, suggesting the development of a Th1 response. Analysis of the cytokines from mice immunized with NP-RAS showed a significant increase in the production of IFN-gamma and a decreased production of IL-10 and IL-4 compared to controls without RAS. These results are similar to those usually obtained using Freund´s adjuvant, known to induce Th1 and CTL responses when co-administered with purified proteins, and suggest that a similar approach may be possible to enhance the performance of a T-cell vaccine containing NP.Fil: Cargnelutti, Diego Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina;Fil: Sanchez, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina;Fil: Alvarez, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;Fil: Boado, Lorena Analía. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;Fil: Mattion, Nora Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;Fil: Scodeller, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina
High clustering rates of multidrug-resistant Mycobacterium tuberculosisgenotypes in Panama
Background: Tuberculosis continues to be one of the leading causes of death worldwide and in the American region. Although multidrug-resistant tuberculosis (MDR-TB) remains a threat to TB control in Panama, few studies have focused in typing MDR-TB strains. The aim of our study was to characterize MDR Mycobacterium tuberculosis clinical isolates using PCR-based genetic markers. Methods: From 2002 to 2004, a total of 231 Mycobacterium tuberculosis isolates from TB cases country-wide were screened for antibiotic resistance, and MDR-TB isolates were further genotyped by double repetitive element PCR (DRE-PCR), (GTG)5-PCR and spoligotyping. Results: A total of 37 isolates (0.85%) were resistant to both isoniazid (INH) and rifampicin (RIF). Among these 37 isolates, only two (5.4%) were resistant to all five drugs tested. Dual genotyping using DRE-PCR and (GTG)5-PCR of MDR Mycobacterium tuberculosis isolates revealed eight clusters comprising 82.9% of the MDR-TB strain collection, and six isolates (17.1%) showed unique fingerprints. The spoligotyping of MDR-TB clinical isolates identified 68% as members of the 42 (LAM9) family genotype.Background: Tuberculosis continues to be one of the leading causes of death worldwide and in the American region. Although multidrug-resistant tuberculosis (MDR-TB) remains a threat to TB control in Panama, few studies have focused in typing MDR-TB strains. The aim of our study was to characterize MDR Mycobacterium tuberculosis clinical isolates using PCR-based genetic markers. Methods: From 2002 to 2004, a total of 231 Mycobacterium tuberculosis isolates from TB cases country-wide were screened for antibiotic resistance, and MDR-TB isolates were further genotyped by double repetitive element PCR (DRE-PCR), (GTG)5-PCR and spoligotyping. Results: A total of 37 isolates (0.85%) were resistant to both isoniazid (INH) and rifampicin (RIF). Among these 37 isolates, only two (5.4%) were resistant to all five drugs tested. Dual genotyping using DRE-PCR and (GTG)5-PCR of MDR Mycobacterium tuberculosis isolates revealed eight clusters comprising 82.9% of the MDR-TB strain collection, and six isolates (17.1%) showed unique fingerprints. The spoligotyping of MDR-TB clinical isolates identified 68% as members of the 42 (LAM9) family genotype
High clustering rates of multidrug-resistant Mycobacterium tuberculosisgenotypes in Panama
Background: Tuberculosis continues to be one of the leading causes of death worldwide and in the American region. Although multidrug-resistant tuberculosis (MDR-TB) remains a threat to TB control in Panama, few studies have focused in typing MDR-TB strains. The aim of our study was to characterize MDR Mycobacterium tuberculosis clinical isolates using PCR-based genetic markers. Methods: From 2002 to 2004, a total of 231 Mycobacterium tuberculosis isolates from TB cases country-wide were screened for antibiotic resistance, and MDR-TB isolates were further genotyped by double repetitive element PCR (DRE-PCR), (GTG)5-PCR and spoligotyping. Results: A total of 37 isolates (0.85%) were resistant to both isoniazid (INH) and rifampicin (RIF). Among these 37 isolates, only two (5.4%) were resistant to all five drugs tested. Dual genotyping using DRE-PCR and (GTG)5-PCR of MDR Mycobacterium tuberculosis isolates revealed eight clusters comprising 82.9% of the MDR-TB strain collection, and six isolates (17.1%) showed unique fingerprints. The spoligotyping of MDR-TB clinical isolates identified 68% as members of the 42 (LAM9) family genotype.Background: Tuberculosis continues to be one of the leading causes of death worldwide and in the American region. Although multidrug-resistant tuberculosis (MDR-TB) remains a threat to TB control in Panama, few studies have focused in typing MDR-TB strains. The aim of our study was to characterize MDR Mycobacterium tuberculosis clinical isolates using PCR-based genetic markers. Methods: From 2002 to 2004, a total of 231 Mycobacterium tuberculosis isolates from TB cases country-wide were screened for antibiotic resistance, and MDR-TB isolates were further genotyped by double repetitive element PCR (DRE-PCR), (GTG)5-PCR and spoligotyping. Results: A total of 37 isolates (0.85%) were resistant to both isoniazid (INH) and rifampicin (RIF). Among these 37 isolates, only two (5.4%) were resistant to all five drugs tested. Dual genotyping using DRE-PCR and (GTG)5-PCR of MDR Mycobacterium tuberculosis isolates revealed eight clusters comprising 82.9% of the MDR-TB strain collection, and six isolates (17.1%) showed unique fingerprints. The spoligotyping of MDR-TB clinical isolates identified 68% as members of the 42 (LAM9) family genotype
Molecular identification of Nocardia species using the sodA gene Identificación molecular de especies de Nocardia utilizando el gen sodA.
Currently for bacterial identification and classification the rrs gene encoding 16S rRNA is used as a reference method for the analysis of strains of the genus Nocardia. However, it does not have enough polymorphism to differentiate them at the species level. This fact makes it necessary to search for molecular targets that can provide better identification. The sodA gene (encoding the enzyme superoxide dismutase) has had good results in identifying species of other Actinomycetes. In this study the sodA gene is proposed for the identification and differentiation at the species level of the genus Nocardia. We used 41 type species of various collections; a 386 bp fragment of the sodA gene was amplified and sequenced, and a phylogenetic analysis was performed comparing the genes rrs (1171 bp), hsp65 (401 bp), secA1 (494 bp), gyrB (1195 bp) and rpoB (401 bp). The sequences were aligned using the Clustal X program. Evolutionary trees according to the neighbour-joining method were created with the programs Phylo_win and MEGA 6. The specific variability of the sodA genus of the genus Nocardia was analysed. A high phylogenetic resolution, significant genetic variability, and specificity and reliability were observed for the differentiation of the isolates at the species level. The polymorphism observed in the sodA gene sequence contains variable regions that allow the discrimination of closely related Nocardia species. The clear specificity, despite its small size, proves to be of great advantage for use in taxonomic studies and clinical diagnosis of the genus Nocardia
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