1 research outputs found
HYPOGLYCEMIC ACTION OF ETHANOLIC EXTRACT OF LEAVES OF OXALIS CORNICULATA LINN. ON NORMAL AND ALLOXAN-INDUCED DIABETIC ALBINO RATS
Objective: The aim of the study is to evaluate hypoglycemic action of Ethanolic extract of leaves of Oxalis corniculata linn. on normal and Alloxan-induced diabetic albino rats.
Methods: Hyperglycemia is induced by use of intraperitoneal injection of Alloxan and Adrenaline. After that test drug Ethanolic extract of leaves of Oxalis corniculata (ELOC) and standard drug Glibenclamide in administered. The hypoglycemic effect of ELOC is compared with the standard drug and control.
Results: Significant hypoglycemic activity of ELOC was seen in Alloxan induced hyperglycemia when blood glucose levels were estimated from different tissues. Also, significant hypoglycemic activity of ELOC was seen in Adrenaline induced hyperglycemia.
Conclusion: Ethanolic extract of leaves of Oxalis corniculata (ELOC) possess hypoglycemic activity.
Key words: hypoglycemic activity, Alloxan, Oxalis corniculat