In Vitro Study of the Proliferation of MG63 Cells Cultured on Five Different Titanium Surfaces

The use of dental implants for prosthetic rehabilitation in dentistry is based on the concept of osteointegration. This concept enables the clinical stability of the implants and a total absence of inflammatory tissue between the implant surface and the bone tissue. For this reason, it is essential to understand the role of the titanium surface in promoting and maintaining or not maintaining contact between the bone matrix and the surface of the titanium implant. Materials and Methods: Five types of titanium discs placed in contact with osteoblast cultures of osteosarcomas were studied. The materials had different roughness. Scanning electron microscopy (SEM) photos were taken before the in vitro culture to analyze the surfaces, and at the end of the culturing time, the different gene expressions of a broad pattern of proteins were evaluated to analyze the osteoblast response, as indicated in the scientific literature. Results: It was demonstrated that the responses of the osteoblasts were different in the five cultures in contact with the five titanium discs with different surfaces; in particular, the response in the production of some proteins was statistically significant. Discussion: The key role of titanium surfaces underlines how it is still possible to carry out increasingly accurate and targeted studies in the search for new surfaces capable of stimulating a better osteoblastic response and the long-term maintenance of osteointegration

Light rays having extreme points with the same spatial coordinates

AbstractIn this paper we deal with lightlike geodesics in Lorentzian manifolds which are closed with respect to the spatial coordinates. We consider the case where the initial point is fixed or moves on a level of a given time function. The case where the initial point is free is also considered, under a periodicity condition on the metric

On the geodesical connectedness for a class of Semi-Riemannian manifolds

AbstractWe prove a variational principle for geodesics on a semi-Riemannian manifold M of arbitrary index k and possessing k linearly independent Killing vector fields that generate a timelike distribution on M. Using such a principle and a suitable completeness condition for M, we prove some existence and multiplicity results for geodesics joining two fixed points of M

Global Existence for Elastic Waves with Memory

We treat the Cauchy problem for nonlinear system of viscoelasticity with memory term. We study the existence and time decay of the solution to this nonlinear problem. The kernel of the memory term includes integrable singularity at zero and polynomial decay at infinity. We prove the existence of a global solution for space dimensions n ≥ 3 and arbitrary quadratic nonlinearities

Global existence for elastic waves with memory

We treat the Cauchy problem for nonlinear system of viscoelasticity with memory term. We study the existence and time decay of the solution to this nonlinear problem. The kernel of the memory term includes integrable singularity at zero and polynomial decay at infinity. We prove the existence of a global solution for space dimensions $ngeq 3$ and arbitrary quadratic nonlinearities

Asymptotic behaviour for linear and nonlinear elastic waves for materials with memory

In this review, we study the Cauchy problem associated to the equation of linear and nonlinear viscoelasticity with memory. Our first point is the study of dispersive properties of the solution to the linear equation of viscoelasticity with memory. The decay estimates obtained in this first part are important to treat the corresponding nonlinear Cauchy problem. The key novelty is the fact that we admit algebraic singularities and decay at infinity for the time dependent functions in the memory kernel. This fact enables one to include models different from the classical viscoelasticity problem, where this kernel is smooth and exponentially decaying in time

Unusual presentation of skin tattoo-associated panuveitis

Aim: We report a case of a young male who developed bilateral panuveitis after extensive tattooing. Design: Case report. Methods: A 22-year-old male with a history of inflamed tattoos presented with pain in both eyes and blurred vision in the left eye. Clinical examination showed ciliary congestion, flare, vitreous cells in both eyes, and posterior synechiae in the left eye. Optic nerve was swollen in both eyes. OCT scans demonstrated subretinal blood, associated with neurosensory macular detachment in the left eye. The skin tattoo biopsy showed a granulomatous inflammation without evidence of sarcoidosis. Long-term corticosteroid therapy allowed a regression of clinical signs and symptoms with full recovery. Conclusion: TAttoo Granulomas with Uveitis (TAGU) is a syndrome with numerous clinical presentations. In our case, optic nerve head oedema and subretinal hemorrhage at the posterior pole were the presentation signs. Ophthalmologists should always consider TAGU as a diagnosis in patients with a history of inflamed tattoos

Disfunzioni sessuali maschili e profili di personalità. Dati preliminari

Introduzione ed Obbiettivi Già nel 1971 Eyesenk ha dimostrato che gli uomini con disfunzioni sessuali (DS) presentavano alti livelli di neuroticismo, inteso come tendenza ad esperire sentimenti di ansia e preoccupazione, se comparati alla popolazione senza DS (1). La relazione tra le DS ed i tratti di personalità è stata da allora scarsamente approfondita in letteratura. Scopo di questo lavoro è di verificare se vi siano dei profili di personalità più frequentemente associati alle principali disfunzioni sessuali maschili (DSM), ovvero la Disfunzione Erettile (DE) e l’Eiaculazione Precoce (EP), con conseguenti ripercussioni sulla pratica clinica. Materiali e metodi A 81 uomini richiedenti visita andrologica tra Novembre 2012 ed Aprile 2013, per DE o EP di origine psicogena (57 DE, 18 EP, 6 EP + DE) , è stato somministrato l’International Index of Erectile Function (IIEF) per DE e il Premature Ejaculation Severity Index (PESI) per EP, insieme ad EPQ-R, un questionario strutturato per la valutazione del profilo di personalità. Questo strumento si avvale di 5 scale corrispondenti a 5 aspetti della personalità più una di controllo. Risultati È emerso che nei soggetti con DE e/o EP, è presente in misura superiore alla popolazione di controllo (PdC) la dimensione di personalità definita estroversione (impazienza, impulsività) con una media dei percentili (MdP), rispetto alla PdC, di 58,12 e mediana 63. Nei pazienti con EP, sono invece presenti in misura superiore alla PdC le dimensioni di personalità tipiche dei soggetti con dipendenze o comportamenti antisociali, con MdP 64,7 e 66,2 e mediana 64 e 70: ciò interpreterebbe la tendenza dei pazienti con EP a cercare la gratificazione il prima possibile, come avviene nei comportamenti di abuso o illegali. I pazienti con EP hanno inoltre ottenuto valori molto bassi nella scala LIE (desiderabilità sociale), indicando un’eccessiva noncuranza del giudizio dell’altro, con una MdP 32,8 e mediana 16. Conclusioni Se i dati preliminari riportati troveranno conferma in una popolazione più estesa, attualmente in osservazione, sarà possibile identificare i sottogruppi di pazienti in cui le componenti stabili della struttura di personalità possano suggerire all’andrologo di avvalersi di un approccio integrato con lo psicosessuologo per la risoluzione della DS del paziente, in particolare laddove la terapia farmacologica non risulti risolutiva. (1)Eysenck HJ. Personality and sexual adjustment. Br J Psychiatry 1971;118:593?608

Effect of the Magnetic Field Generated by a New NeFeB Cover Screw on Bone Healing around Endosseous Implants: A Case Series Report from Dental Practice

This study aimed to investigate the effect of static magnetic field (SMF) generated by innovative cover screws made of NeFeB on early bone healing around dental implants. The study was carried out on humans in a private dental practice. Eight 3i implants (Biomet, Palm Beach, FL, USA) were placed in the posterior mandible at 3.6 and 3.7. The control implants were closed with a conventional screw (G1), while the test implants were closed with a Supercharged((R)) screw (G2). Both groups were compared for stability at 0, 7, 14, 21, 50, and 90 days using a resonant frequency analyzer with Ostell Mentor (Osstell AB, Gothenburg, Sweden). After 50 days, the Supercharged((R)) cover screw was removed. A significant increase in implant stability quotient (ISQ), corresponding to a lower degree of bone resorption, was observed in G2 throughout the follow-up period (p < 0.05), while an initial ISQ decrease was observed until day 21 in G1. In conclusion, the effect of SMF seems to be in the early stages of osseointegration and increases the stability of dental implants