Enquête sur l’association entre les habitudes alimentaires, l’anthropométrie et le cancer colorectal: Etude cas-témoins dans une population de l’Est Algérien 2016-2017 [Survey on the association between eating habits, anthropometry and colorectal cancer: Case-control study in a population of eastern Algeria 2016-2017]

Résumé Introduction. Des facteurs comme l’obésité et l’alimentation sont impliqués dans la carcinogenèse colique. Objectif. Une étude rétrospective cas-témoins est menée afin d’évaluer l’association de ces facteurs avec le cancer colorectal (CCR) dans une population de l’Est Algérien. Matériel et méthodes. L’enquête a été réalisée entre avril 2016 et août 2017, au niveau de l'Etablissement Public Hospitalier de Bekaria à Tébessa et des Centres Anti-Cancer de Batna et d’Annaba. Soixante quatre patients atteints de CCR âgés de 51±12 et 64 témoins dont l’âge moyen était de 51±17 ans ont été recrutés. Le questionnaire utilisé a permis de collecter les informations concernant l’âge, le sexe, les mesures anthropométriques, les habitudes alimentaires et la fréquence de consommation de quelques aliments. Résultats. Une association significative est notée entre l’obésité et la prévalence du CCR (37,5 % des patients vs 20,31 % des témoins, p=0,048). L’indice de masse corporelle (IMC) moyen des patients était plus élevé que celui des témoins. La prévalence du cancer atteint son maximum entre 50 et 59 ans. La consommation des céréales et des œufs est retenue comme facteur protecteur du CCR (p=0,046 et 0,028). Les témoins consomment plus de pâtes que les patients (P=0,054). Conclusion. Cette étude met en évidence l’association entre le cancer colorectal, l’obésité et la consommation de certains aliments chez les patients atteints de CCR. [Abstract Introduction. Factors such obesity and diet are involved in colon carcinogenesis. Objective. A retrospective case-control study was done to evaluate the association of these factors with colorectal cancer (CRC) in eastern Algeria population. Material and methods. This study was conducted between April 2016 and August 2017, at the Bekaria public hospital in Tebessa, and the Anti-Cancer Centers of Batna and Annaba. Sixty four patients with CRC aged 51±12 years and 64 controls with mean age of 51±17 years. The questionnaire used allowed to collect the following informations: age, gender, anthropometric measurements, eating habits, and consumption frequency of some foods. Results. A significant association was found between obesity and prevalence of CRC (37.5% vs 20.3%, p=0.048). The average body mass index (BMI) of patients was higher than that of the controls. The prevalence of cancer reached its maximum between 50 and 59 years old. Consumption of cereals and eggs was retained as a protective factor for CRC (p=0.046 and p=0.028). Controls consumed more pasta than CRC patients (p=0.054). Conclusion. This study highlights the association between colorectal cancer, obesity and the consumption of certain foods in patients with CRC.

Colorectal cancer: physical activity, obesity and consumption of foods a case-control study in the east of Algeria

Purpose: To evaluate the role of dietary components, physical activity, smoking and Obesity in colorectal cancer.Materials and methods: With a population-based case-control study, 49 colorectal cancer patients and 72 controls were interviewed with uniform questionnaires. Conditional logistic regression was used for multivariate analysis of colorectal cancer. A total of 121 pairs of case controls were interviewed.Results: Relationship between body mass index (BMI) and colorectal cancer was shown in this study, obesity was shown in 21 patients (42.86) before cancer and in 0% of patients during colorectal cancer. Physical activity was a significant risk factor p < 0.0001. Malnutrition was noted in 48 patients (97. 96%) according to Brachial muscular circumference in patients with colorectal cancer (p = 0.002). Daily consumption of sugar Khi² of Wald (5.423) and butter Khi² of Wald (7.694) is higher in cases than in controls.  During that time, high daily consumption of pasta (p = 0.018) and vegetables (p = 0.045) was a protective factor for colorectal cancer.Conclusion: Colorectal cancer in Algeria was related to dietary and environmental factors. The research results support the colorectal cancer etiological hypothesis of deficiency vegetable and high consumption of lipids and sugar.  Obesity and lack of physical activity were also correlated with colorectal cancer