8 research outputs found

    Additional file 1: Figure S1. of Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model

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    Validation of the mice as its own control in mice pre-irradiated at the right mammary gland. D2A1 tumor volumes of sham irradiated animals (sham tumors) were compared to control tumors (left side) of pre-irradiated animals. Error bars indicate s.e.m. for n = 6 to 15 animals for each group. (TIF 224 kb

    Additional file 5: Figure S5. of Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model

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    Hormonal status of D2A1 cell line was confirmed by immunohistochemistry as described in Materials and Methods. No nuclear (ER and PR) as well as membrane (HER2) staining were observed. D2A1 cells were then revealed to be triple negative by a pathologist of our institution. (TIF 9131 kb

    Additional file 4: Figure S4. of Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model

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    Quantitative densitometry from Western blots of the expression of (A) LCB3I, (B) LCB3II (Sham-CQ 60 vs IRR-CQ 60; P = 0.0024, CTL-CQ 60 vs IRR-CQ 60; P = 0.0182, IRR-VH vs IRR-CQ 60; P = 0.0009) and (C) p62 autophagy markers calculated using ImageJ Gel Analyze function
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