Review on Phytopharmacological Activity of Curcuma amada Roxb. (Mango ginger)

Plants have been an essential part of our daily lives since early advancement. Since prehistoric times, they’vebeen found and employed in traditional medicine. The plant has been used as a medication for diseases and disorders. Curcuma amada Roxb. (Mango ginger) of the family Zingiberaceae belongs to the genus Curcuma, a beneficial plant in the indigenous system of medicine. It has a significant role in food as well as in pharmaceuticals. Some of its outstanding medical characteristics, including antioxidant, antiviral, antibacterial and anti-inflammatory properties, have been reported. Dermatological issues like eczema, itching, and digestive problems are treated with rhizomes. The plant parts are rich in starch, phenolic acids, curcuminoids, volatile oils, minerals, vitamins and phytoconstituents like labdane diterpene dialdehyde, amadaldehyde, zederone, amadannulen, difurocumenonol. C. amada is used in Ayurveda and Unani medical systems as an aphrodisiac, expectorant, appetizer, diuretic, emollient, antipyretic as well as to treat asthma, skin ailments, itching, biliousness, bronchitis, hiccough, and inflammation caused by accidents. This research focused on the main active ingredients, their biological activities and therapeutic capabilities, traditional use and proven pharmacological aspects that may be important from a pharmacological standpoint

Recent Advancements in Phyto Component Based Nanocarriers for Improved Treatment of Brain Disorders

Effective treatment of brain disorders remains a tough task in medical science. Age-old brain disorders like Parkinson’s (PD) and Alzheimer’s (AD) are yet to be managed effectively in spite of fabulous scientific progress over the last decades. Presently available treatment strategies have been found insufficient to tackle the out bursting cases of AD and PD. Indeed, presence of blood-brain barrier (BBB) highly hijacks success of conventional drug therapy. In this regard, phyto bioactive components delivered through nanocarrier (NCs) systems hold ray of hope in improving treatment benefits in brain disorders. Several NCs including polymeric nanoparticles, nanoliposomes, micelles, dendrimers have now being heavily researched to effectively deliver the phyto active components to brain tissue. NCs owing to their structural and physiological uniqueness have now been evolved with great potential for the treatment of brain disorders. Functionalization of brain specific ligands on the surface of NCs further makes them target specific, which might significantly improve bioavailability or reduce the off-target adverse effects. This chapter primarily focuses on recent advancements in phyto component loaded NCs employed for the treatment of brain disorders. The chapter especially covers existing impediments of phyto component based NCs for Parkinson and Alzheimer’s disease