UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION FOR TELMISARTAN IN BULK AND TABLET DOSAGE FORM

Objective: To develop UV spectrophotometric method for determination of Telmisartan in bulk and tablet dosage form in 0.1 N NaOH by two methods. Methods: Method A involve Absorption maxima method based on the measurement of absorbance at 295 nm that is the λmax of Telmisartan, while Method B involved Area under the curve based on the measurement of AUC in the range of 275-310 nm. Results: Both methods obey Beer- Lamberts law in concentration range of 2-12 µg/ml. Methods were validated as per ICH guidelines in terms of accuracy, linearity and precision. Conclusion: The proposed methods found to be simple, accurate, precise, reproducible, economic and suitable for routine quality control analysis

Application of Heuristic Search Algorithm to Design Automatic Generation Control in Power System

This paper presents a Heuristic Search Algorithm, Conventional Particle Swarm Optimization (CPSO) which is employed to design Automatic Generation Control (AGC) for an isolated power system to minimize the variation in frequency due to changes in load demand. Further, Advanced Particle Swarm Optimization (APSO) with a velocity update strategy is introduced to ensure that the particles will orbit toward their optimum point quickly which guarantees faster convergence

Design and Simulation of Boost Derived Hybrid Converter for Nano Grid Applications

—This work presents the proficiency in writing C code using Code::Blocks. Code::Blocks is a free C, C++ and Fortran IDE built to meet the most demanding needs of its users. It runs on Linux, Mac, Windows (uses wxWidgets). It is designed to be very extensible and fully configurable. Code::Blocks is used to program hybrid converter topology which can supply simultaneous dc and ac loads from a single dc sources like battery, photovoltaic cells, fuel cells etc. This topology is realized by replacing the controlled switched of single-switch boost converter with a voltage-sourceinverter bridge network. The resulting hybrid converter requires lesser number of switches to provide dc and ac output with an increased reliability, resulting from its inherent shoot-through in the inverter bridge. Such multi output converter with better power processing density and reliability can be well suited for system with simultaneous dc and ac loads. This converter is called Boost derived hybrid converter (BDHC). As it is obtained from the conventional boost topology. The study state behaviour of this BDHC will is presented. And also a suitable pulse width modulation (PWM) controlled strategy will be adapted based upon unipolar sine PWM. Simulation of BDHC is carried out. The BDHC converter is able to supply dc and ac loads from a 12V dc input.The programming results are ploted using Gnuplot. Gnuplot is a free, command- driven, interactive, function and data plotting program