The legacy of nineteenth-century replicas for object cultural biographies : lessons in duplication from 1830s Fife

Peer reviewedPostprin

PAC Learing of One-Dimensional Patterns

Developing the ability to recognize a landmark from a visual image of a robot\u27s current location is a fundamental problem in robotics. We consider the problem of PAC-learning the concept class of geometric patterns where the target geometric pattern is a configuration of k points on the real line. Each instance is a configuration of n points on the real line, where it is labeled according to whether or not it visually resembles the target pattern. To capture the notion of visual resemblance we use the Hausdorff metric. Informally, two geometric patterns P and Q resemble each othe runder the Hausdorff metric, if every point on one pattern is close to some point on the other pattern. We relate the concept class of geometric patterns to the landmark recognition problem and then present a polynomial-time algorithm that PAC-learns the class of one-dimensional geometric patterns. We also present some experimental results on how our algorithm performs

A Pervasive Technology Solution for Diabetes Using Gestational Diabetes as a Model

Diabetes is one of the leading chronic diseases affecting Australians and its prevalence continues to rise. Diabetes is therefore becoming a serious challenge for both the quality of healthcare and expenditure in the Australian healthcare system. The goal of this study is to investigate the development and application of a pervasive wireless technology solution to facilitate the effective management of diabetic patients, using the context of the care of women with gestational diabetes, a form of diabetes that affects up to 8% of pregnant women as a test case. Integral to the success of this solution is the unique software technology developed by INET to enable mobile phones to facilitate superior diabetes self-management

The legacy of nineteenth-century replicas for object cultural biographies: lessons in duplication from 1830s Fife

This article was the first award winner of the Trust's Murray Prize for History awarded in 2015, and is reprinted in this Annual Report and Yearbook. Because of space limitations its first two illustrations have been omitted and there have been minor deletions to the text. © FOSTER, S.M., BLACKWELL, A. and GOLDBERG, M., 2014. First published in Journal of Victorian Culture, 19(2), pp. 137-160 (http://dx.doi.org/10.1080/13555502.2014.919079) and reproduced with permission. Abstract: The St Andrews Sarcophagus and Norrie's Law hoard are two of the most important surviving Pictish relics from early medieval Scotland. The entanglement of their later biographies is also of international significance in its own right. Soon after discovery in nineteenth-century Fife, both sets of objects were subject, in 1839, to an exceptionally precocious, documented programme of replication through the enlightened auspices of an under-appreciated antiquarian, George Buist. This well-evidenced case study highlights how and why replicas, things that are widely prevalent in Europe and beyond, are a ‘thick' and relatively unexplored seam of archaeological material culture that we ignore at our peril. These particular replications also offer new insights into the vision, intellectual and practical energies of early antiquarian societies, and their web of connections across Britain and Ireland

An In vivo Model for Short-Term Evaluation of the Implantation Effects of Biomolecules or Stem Cells in the Dental Pulp

The continuously growing rodent incisor is a widely used model to investigate odontogenesis and mineralized tissue formation. This study focused on evaluating the mouse mandibular incisor as an experimental biological tool for analyzing in vivo the capacity of odontoblast-like progenitors or bioactive molecules to contribute to reparative dentinogenesis. We describe here a surgical procedure allowing direct access to the forming part of the incisor dental pulp Amelogenin peptide A+4 adsorbed on agarose beads, or dental pulp progenitor cells were implanted in the pulp following this procedure. After 10 days A+4 induced the formation of an osteodentin occluding almost the totality of the pulp compartment. Implantation of progenitor cells leads to formation of islets of osteodentin-like structures located centrally in the pulp. These pilot studies validate the incisor as an experimental model to test the capacity of progenitor cells or bioactive molecules to induce the formation of reparative dentin

New insights into lithology and hydrogeology of the northern Newark Rift Basin

The marginal facies of the Triassic rift basins in the eastern United States are poorly documented, particularly on the hinge or hanging wall margins. This study presents a lithological description and multiscale petrophysical analysis of basement rocks, overlying marginal facies of the early synrift strata, and the basal contact of the Palisade Sill that were drilled and cored in the northeastern part of the Newark Basin, near its terminus. The expression of the Stockton Formation differs from that in the central basin in having thinner layers, with uncertain temporal relationship to the type area. The bottom 50 m is lithologically distinct with brick-red to dark-purple mudstones and sandstones, abundant gypsum-filled fractures, and a thin zone with anomalously high uranium concentration, not associated with organic-rich mudstones as other occurrences in the basin. The crystalline basement is apparently Fordham gneiss, overlain by a thin sandstone layer and a dark-purple hydrophilic mudstone. Despite the abundance of coarse-grained strata and multiple sets of tectonic fractures, hydraulically transmissive zones are sparse, and do not uniquely correlate to fracture and/or matrix characteristics. Enhanced transmissivity may exist along intrusion boundaries due to enhanced thermal fracturing, but more hydraulic data are needed to verify it. Comparison of petrophysical data in two boreholes ∼210 m apart shows no direct correlation of individual lithological units and their hydraulic properties, although the overall formation characteristics are similar. The results highlight challenges for outcrop correlation at the marginal edges of the rift basins and estimating reservoir properties of these heterogeneous formations

Enhanced surveillance of COVID-19 in Scotland: population-based seroprevalence surveillance for SARS-CoV-2 during the first wave of the epidemic

This work was funded by the Scottish Government.Objectives: The impact of the COVID-19 pandemic in Scotland has been amongst the most severe in Europe. Serological surveillance is critical to determine the overall extent of infection across populations and to inform the public health response. This study aimed to estimate the proportion of people who have antibodies to SARS-CoV-2 ('seroprevalence') in the general population of Scotland and to see if this changes over time. Study Design/Methods: Between International Organization for Standardization (ISO) week 17 (i.e. week commencing 20th April) and ISO week 25 (week commencing 15 June), 4751 residual blood samples were obtained from regional biochemistry laboratories in six participating regional health authority areas covering approximately 75% of the Scottish population. Samples were tested for the presence of anti-SARS-CoV-2 IgG antibodies using the LIAISON®SARS-CoV-2 S1/S2 IgG assay (DiaSorin, Italy). Seroprevalence rates were adjusted for the sensitivity and specificity of the assay using Bayesian methods. Results: The combined adjusted seroprevalence across the study period was 4.3% (95% confidence interval: 4.2%-4.5%). The proportion varied each week between 1.9% and 6.8% with no difference in antibody positivity by age, sex or geographical area. Conclusions: At the end of the first wave of the COVID-19 pandemic, only a small fraction of the Scottish population had antibodies to SARS-CoV-2. Control of COVID-19 requires the ability to detect asymptomatic and mild infections that would otherwise remain undetected through existing surveillance systems. This is important to determine the true number of infections within the general population which, in turn, can help to understand transmission, inform control measures and provide a denominator for the estimation of severity measures such as the proportion of infected people who have been hospitalised and/or have died.PostprintPeer reviewe

Prevalence of Common Mental Disorders in a Rural District of Kenya, and Socio-Demographic Risk Factors

Association between common mental disorders (CMDs), equity, poverty and socio-economic functioning are relatively well explored in high income countries, but there have been fewer studies in low and middle income countries, despite the considerable burden posed by mental disorders, especially in Africa, and their potential impact on development. This paper reports a population-based epidemiological survey of a rural area in Kenya. A random sample of 2% of all adults living in private households in Maseno, Kisumu District of Nyanza Province, Kenya (50,000 population), were studied. The Clinical Interview Schedule-Revised (CIS-R) was used to determine the prevalence of common mental disorders (CMDs). Associations with socio-demographic and economic characteristics were explored. A CMD prevalence of 10.8% was found, with no gender difference. Higher rates of illness were found in those who were of older age and those in poor physical health. We conclude that CMDs are common in Kenya and rates are elevated among people who are older, and those in poor health

The transition into adoptive parenthood: adoption as a process of continued unsafe uncertainty when family scripts collide

Our prospective study investigated couples’ expectations of adoptive parenthood and explored how these changed with their actual experience of parenthood. Six heterosexual couples were interviewed just before placement began and six months after the children had arrived. Interpretative Phenomenological Analysis (IPA) was used to analyse both sets of interview data. Expectations of adoptive parenthood mostly transformed smoothly into adoption experience for couples but challenges were experienced when family scripts collided and a continued feeling of unsafe uncertainty then prevailed within these newly formed family systems. Family script collision seemed a particular problem for couples adopting sibling pairs. To further professional practice in working with families over the transition to adoptive parenting we suggest that professionals keep in mind a framework that includes: Internal and external world influences on family members, Intergenerational issues, Family scripts, and the Structural challenges of adoption (IIFS)

The thing about replicas - why historic replicas matter

Reproduction of archaeological material was a significant and serious enterprise for antiquarians and museums in the long nineteenth century. Embedding many stories and embodying considerable past human energy, behind their creation, circulation, use and after-life lies a series of specific social networks and relationships that determined why, when and in what circumstances they were valued, or not. Summarising the context of their production, circulation and changing fortunes, this paper introduces the ways in which they are important and the specific benefits and aspects of a biographical approach to their study. Beyond the evidential, the study of existing replicas provides a historical and contemporary laboratory in which to explore the concepts of value and authenticity, and their application in cultural heritage and collections management, offering us a richer insight into the history of ourselves as archaeologists and curators