Vital and functional outcomes of the first-ever hemispheric stroke, epidemiological comparative study between Kunming (China) and Limoges (France)

AbstractBackgroundClinical outcomes and socioeconomic consequences after a stroke may differ between regions.MethodsOne cohort was established prospectively in Kunming (China) to compare with a cohort of 156 stroke patients included in Limoges (France). During 1 year, patients hospitalized within 48hours for a first-ever hemispheric stroke were included. Demographic data and neurocardiovascular risk factors were registered. Hemiplegia was evaluated. Functional outcome was assessed using the Barthel Index (BI) after 3 months.ResultsOne hundred and eighteen patients were included in Kunming. Patients of Kunming were younger (61.4±13.4 vs 72.3±14.6 years in Limoges, P<0.0001), more involved in professional activity (36.4% vs 12.8%, P<0.0001). Survival analysis indicated that mortality did not differ between cohorts, but independently predicted by coma at the 2nd day (HR=9.33, 95% CI [4.39, 19.78]) and age>70 years (HR=6.29, 95% CI [2.36, 16.59]). Despite a better baseline BI for patients of Kunming (50.0±34.9 vs 37.4±34.2, P=0.0031), after adjustment for confusing, patients in Limoges had a 2.11 OR 95% CI [1.03, 4.31]) to reach a BI>80 at 3 months.ConclusionsFunctional recovery for patients of Kunming was not as good as expected. The socioeconomic consequences of stroke in Kunming are significant as they involved younger subjects who were still in work

The approach to thermalization in the classical phi^4 theory in 1+1 dimensions: energy cascades and universal scaling

We study the dynamics of thermalization and the approach to equilibrium in the classical phi^4 theory in 1+1 spacetime dimensions. At thermal equilibrium we exploit the equivalence between the classical canonical averages and transfer matrix quantum traces of the anharmonic oscillator to obtain exact results for the temperature dependence of several observables, which provide a set of criteria for thermalization. We find that the Hartree approximation is remarkably accurate in equilibrium. The non-equilibrium dynamics is studied by numerically solving the equations of motion in light-cone coordinates for a broad range of initial conditions and energy densities.The time evolution is described by several stages with a cascade of energy towards the ultraviolet. After a transient stage, the spatio-temporal gradient terms become larger than the nonlinear term and a stage of universal cascade emerges.This cascade starts at a time scale t_0 independent of the initial conditions (except for very low energy density). Here the power spectra feature universal scaling behavior and the front of the cascade k(t) grows as a power law k(t) sim t^alpha with alpha lesssim 0.25. The wake behind the cascade is described as a state of Local Thermodynamic Equilibrium (LTE) with all correlations being determined by the equilibrium functional form with an effective time dependent temperatureTeff(t) which slowly decreases as sim t^{-alpha}.Two well separated time scales emerge while Teff(t) varies slowly, the wavectors in the wake with k < k(t) attain LTE on much shorter time scales.This universal scaling stage ends when the front of the cascade reaches the cutoff at a time t_1 sim a^{-1/alpha}. Virialization starts to set much earlier than LTE. We find that strict thermalization is achieved only for an infinite time scale.Comment: relevance for quantum field theory discussed providing validity criteria. To appear in Phys. Rev.

Dressing Up the Kink

Many quantum field theoretical models possess non-trivial solutions which are stable for topological reasons. We construct a self-consistent example for a self-interacting scalar field--the quantum (or dressed) kink--using a two particle irreducible effective action in the Hartree approximation. This new solution includes quantum fluctuations determined self-consistently and nonperturbatively at the 1-loop resummed level and allowed to backreact on the classical mean-field profile. This dressed kink is static under the familiar Hartree equations for the time evolution of quantum fields. Because the quantum fluctuation spectrum is lower lying in the presence of the defect, the quantum kink has a lower rest energy than its classical counterpart. However its energy is higher than well-known strict 1-loop results, where backreaction and fluctuation self-interactions are omitted. We also show that the quantum kink exists at finite temperature and that its profile broadens as temperature is increased until it eventually disappears.Comment: 13 pages, latex, 3 eps figures; revised with yet additional references, minor rewordin

Out-of-equilibrium evolution of quantum fields in the hybrid model with quantum back reaction

The hybrid model with a scalar "inflaton" field coupled to a "Higgs" field with a broken symmetry potential is one of the promising models for inflation and (p)reheating after inflation. We consider the nonequilibrium evolution of the quantum fields of this model with quantum back reaction in the Hartree approximation, in particular the transition of the Higgs field from the metastable "false vacuum" to the broken symmetry phase. We have performed the renormalization of the equations of motion, of the gap equations and of the energy density, using dimensional regularization. We study the influence of the back reaction on the evolution of the classical fields and of the quantum fluctuations. We observe that back reaction plays an important role over a wide range of parameters. Some implications of our investigation for the preheating stage after cosmic inflation are presented.Comment: 35 pages, 16 eps figures, revtex4; v2: typos corrected and references added, accepted for publication in Physical Review

Nonequilibrium Evolution of Correlation Functions: A Canonical Approach

We study nonequilibrium evolution in a self-interacting quantum field theory invariant under space translation only by using a canonical approach based on the recently developed Liouville-von Neumann formalism. The method is first used to obtain the correlation functions both in and beyond the Hartree approximation, for the quantum mechanical analog of the $\phi^{4}$ model. The technique involves representing the Hamiltonian in a Fock basis of annihilation and creation operators. By separating it into a solvable Gaussian part involving quadratic terms and a perturbation of quartic terms, it is possible to find the improved vacuum state to any desired order. The correlation functions for the field theory are then investigated in the Hartree approximation and those beyond the Hartree approximation are obtained by finding the improved vacuum state corrected up to ${\cal O}(\lambda^2)$. These correlation functions take into account next-to-leading and next-to-next-to-leading order effects in the coupling constant. We also use the Heisenberg formalism to obtain the time evolution equations for the equal-time, connected correlation functions beyond the leading order. These equations are derived by including the connected 4-point functions in the hierarchy. The resulting coupled set of equations form a part of infinite hierarchy of coupled equations relating the various connected n-point functions. The connection with other approaches based on the path integral formalism is established and the physical implications of the set of equations are discussed with particular emphasis on thermalization.Comment: Revtex, 32 pages; substantial new material dealing with non-equilibrium evolution beyond Hartree approx. based on the LvN formalism, has been adde

Quantum dynamics and thermalization for out-of-equilibrium phi^4-theory

The quantum time evolution of \phi^4-field theory for a spatially homogeneous system in 2+1 space-time dimensions is investigated numerically for out-of-equilibrium initial conditions on the basis of the Kadanoff-Baym equations including the tadpole and sunset self-energies. Whereas the tadpole self-energy yields a dynamical mass, the sunset self-energy is responsible for dissipation and an equilibration of the system. In particular we address the dynamics of the spectral (`off-shell') distributions of the excited quantum modes and the different phases in the approach to equilibrium described by Kubo-Martin-Schwinger relations for thermal equilibrium states. The investigation explicitly demonstrates that the only translation invariant solutions representing the stationary fixed points of the coupled equation of motions are those of full thermal equilibrium. They agree with those extracted from the time integration of the Kadanoff-Baym equations in the long time limit. Furthermore, a detailed comparison of the full quantum dynamics to more approximate and simple schemes like that of a standard kinetic (on-shell) Boltzmann equation is performed. Our analysis shows that the consistent inclusion of the dynamical spectral function has a significant impact on relaxation phenomena. The different time scales, that are involved in the dynamical quantum evolution towards a complete thermalized state, are discussed in detail. We find that far off-shell 1 3 processes are responsible for chemical equilibration, which is missed in the Boltzmann limit. Finally, we address briefly the case of (bare) massless fields. For sufficiently large couplings $\lambda$ we observe the onset of Bose condensation, where our scheme within symmetric \phi^4-theory breaks down.Comment: 77 pages, 26 figure

Formation of topological defects in gauge field theories

When a symmetry gets spontaneously broken in a phase transition, topological defects are typically formed. The theoretical picture of how this happens in a breakdown of a global symmetry, the Kibble-Zurek mechanism, is well established and has been tested in various condensed matter experiments. However, from the viewpoint of particle physics and cosmology, gauge field theories are more relevant than global theories. In recent years, there have been significant advances in the theory of defect formation in gauge field theories, which make precise predictions possible, and in experimental techniques that can be used to test these predictions in superconductor experiments. This opens up the possibility of carrying out relatively simple and controlled experiments, in which the non-equilibrium phase transition dynamics of gauge field theories can be studied. This will have a significant impact on our understanding of phase transitions in the early universe and in heavy ion collider experiments. In this paper, I review the current status of the theory and the experiments in which it can be tested.Comment: Review article, 43 pages, 7 figures. Minor changes, some references added. Final version to appear in IJMP

Full Spectrum Archaeology

Full Spectrum Archaeology (FSA) is an aspiration stemming from the convergence of archaeology’s fundamental principles with international heritage policies and community preferences. FSA encompasses study and stewardship of the full range of heritage resources in accord with the full range of associated values and through the application of treatments selected from the full range of appropriate options. Late modern states, including British Columbia, Canada, nominally embrace de jure heritage policies consonant with international standards yet also resist de facto heritage management practice grounded in professional ethics and local values and preferences. In response, inheritor communities and their allies in archaeology are demonstrating the benefits of FSA and reclaiming control over cultural heritage. Archaeology and heritage management driven by altruistic articulation of communal, educational, scientific and other values further expose shortcomings and vulnerabilities of late modern states as well as public goods in and from FSA

Turbulent Thermalization

We study, analytically and with lattice simulations, the decay of coherent field oscillations and the subsequent thermalization of the resulting stochastic classical wave-field. The problem of reheating of the Universe after inflation constitutes our prime motivation and application of the results. We identify three different stages of these processes. During the initial stage of ``parametric resonance'', only a small fraction of the initial inflaton energy is transferred to fluctuations in the physically relevant case of sufficiently large couplings. A major fraction is transfered in the prompt regime of driven turbulence. The subsequent long stage of thermalization classifies as free turbulence. During the turbulent stages, the evolution of particle distribution functions is self-similar. We show that wave kinetic theory successfully describes the late stages of our lattice calculation. Our analytical results are general and give estimates of reheating time and temperature in terms of coupling constants and initial inflaton amplitude.Comment: 27 pages, 13 figure