223 research outputs found
Reliability analysis of solar-gas hybrid receivers for Central Tower Plants
A novel Solar-Gas Hybrid Receiver (SGHR) that combines the function of a solar receiver and a gas boiler in a single device is presented. This concept requires less equipment and maintenance compared to the Solar Gas Hybrid(SGH) concept, in which the boiler and the solar receiver (SR) are independent devices. The economic benefit is attributed to the increased sharing of infrastructures. Additionally, it has less thermal stress, cycles and shocks, which reduce the failure risk. However, the additional benefit in the reliability of these receivers has not been analyzed so far. In this work, a mathematical model of SGHR is presented. It determines the stress in steady state which is used to estimate the allowable transient stress in order to achieve the required 30 years life design. The results show that the SGHR is exposed to lower thermal stress due to much better temperature distribution. Moreover the higher …info:eu-repo/semantics/publishedVersio
Intra-arterial vasodilators infusion for management of reversible cerebral vasoconstriction syndrome in a 12-year-old girl: A case report.
Reversible cerebral vasoconstriction syndrome (RCVS) is a vascular disease characterized by diffuse transient vasoconstriction and vasodilatation of the cerebral arteries. It is commonly associated with recurrent severe acute headaches with or without focal neurological deficits due to hemorrhages, infarcts, and even posterior reversible encephalopathy syndrome. The optimal management of acute neurologic deficits caused by RCVS is still uncertain. Calcium channel blockers (CCBs) such as nimodipine or verapamil have been reported to be effective in adult series. Intra-arterial injection of nimodipine, verapamil, and milrinone has recently been demonstrated to be safe and effective for treating severe segmental vasoconstriction in adults. CCBs are the most used treatment in the available pediatric literature. Intra-arterial vasodilators have been reported in some rare pediatric reports with more severe diseases, but their utility is still under investigation. We report a case of a 12-year-old girl who underwent a severe course of RCVS complicated by multiple cerebral infarcts, treated by several sessions of intra-arterial vasodilators infusion
Reliability analysis of Solar-Gas Hybrid Receivers for central tower plants
A novel Solar-Gas Hybrid Receiver (SGHR) that combines the function of a solar receiver and a gas boiler in a single device is
presented. This concept requires less equipment and maintenance compared to the Solar Gas Hybrid (SGH) concept, in which the
boiler and the solar receiver (SR) are independent devices. The economic benefit is attributed to the increased sharing of
infrastructures. Additionally, it has less thermal stress, cycles and shocks, which reduce the failure risk. However, the additional
benefit in the reliability of these receivers has not been analyzed so far. In this work, a mathematical model of SGHR is
presented. It determines the stress in steady state which is used to estimate the allowable transient stress in order to achieve the
required 30 years life design. The results show that the SGHR is exposed to lower thermal stress due to much better temperature
distribution. Moreover the higher absorber heat flux of SGHR is translated in a higher mechanical stress with could jeopardizes
the durability. However the reduced number of cycles and the lower thermal stress of a SGHR allows higher transient stresses
than the conventional tube type solar receiver, which lead to more reliable and efficient designs
Real-Time DSP-Free 100Gbit/s/λ PAM-4 Fiber Access Link using EML and Direct Detection
A 100 Gbit/s/ λ PAM-4 fiber link with an optical budget of 30 dB and 20 km fiber reach is achieved in real time experiments. This is compliant with class A (20 dB) point to point (PtP) applications as mobile fronthaul for example, and with class N1 (29 dB) point to multipoint (PtMP) for residential market. We used an integrated externally modulated laser, an analog pre-equalizer, an optical booster amplifier and/or non-filtered preamplifier and direct detection without any digital signal processing (whether real-time or offline)
Procedural Complications During Early Versus Late Endovascular Treatment in Acute Stroke: Frequency and Clinical Impact
BACKGROUND AND PURPOSE: Endovascular treatment (EVT) in acute ischemic stroke is effective in the late time window in selected patients. However, the frequency and clinical impact of procedural complications in the early versus late time window has received little attention. METHODS: We retrospectively studied all acute ischemic strokes from 2015 to 2019 receiving EVT in the Acute Stroke Registry and Analysis of Lausanne. We compared the procedural EVT complications in the early (<6 hours) versus late (6-24 hours) window and correlated them with short-term clinical outcome. RESULTS: Among 695 acute ischemic strokes receiving EVT (of which 202 were in the late window), 113 (16.3%) had at least one procedural complication. The frequency of each single, and for overall procedural complications was similar for early versus late EVT (16.2% versus 16.3%, Padj=0.90). Procedural complications lead to a significantly less favorable short-term outcome, reflected by the absence of National Institutes of Health Stroke Scale improvement in late EVT (delta-National Institutes of Health Stroke Scale-24 hours, -2.5 versus 2, Padj=0.01). CONCLUSIONS: In this retrospective analysis of consecutive EVT, the frequency of procedural complications was similar for early and late EVT patients but very short-term outcome seemed less favorable in late EVT patients with complications
Early-versus-Late Endovascular Stroke Treatment: Similar Frequencies of Nonrevascularization and Postprocedural Cerebrovascular Complications in a Large Single-Center Cohort Study.
Endovascular treatment of acute ischemic stroke is now performed more frequently in the late window in radiologically selected patients. However, little is known about whether the frequency and clinical impact of incomplete recanalization and postprocedural cerebrovascular complications differ between early and late windows in the real world.
We retrospectively reviewed all patients with acute ischemic stroke receiving endovascular treatment within 24 hours from 2015 to 2019 and included in the Acute STroke Registry and Analysis of Lausanne. We compared rates of incomplete recanalization and postprocedural cerebrovascular complications (parenchymal hematoma, ischemic mass effect, and 24-hour re-occlusion) in the early (<6 hours) versus late window (6-24 hours, including patients with unknown onset) populations and correlated them with the 3-month clinical outcome.
Among 701 patients with acute ischemic stroke receiving endovascular treatment, 29.2% had late endovascular treatment. Overall, incomplete recanalization occurred in 56 patients (8%), and 126 patients (18%) had at least 1 postprocedural cerebrovascular complication. The frequency of incomplete recanalization was similar in early and late endovascular treatment (7.5% versus 9.3%, adjusted P =.66), as was the occurrence of any postprocedural cerebrovascular complication (16.9% versus 20.5%, adjusted P = .36). When analyzing single postprocedural cerebrovascular complications, rates of parenchymal hematoma and ischemic mass effect were similar (adjusted P = .71, adjusted P = .79, respectively), but 24-hour re-occlusion seemed somewhat more frequent in late endovascular treatment (4% versus 8.3%, unadjusted P = .02, adjusted P = .40). The adjusted 3-month clinical outcome in patients with incomplete recanalization or postprocedural cerebrovascular complications was comparable between early and late groups (adjusted P = .67, adjusted P = .23, respectively).
The frequency of incomplete recanalization and of cerebrovascular complications occurring after endovascular treatment is similar in early and well-selected late patients receiving endovascular treatment. Our results demonstrate the technical success and safety of endovascular treatment in well-selected late patients with acute ischemic stroke
Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines
BACKGROUND: Acute malaria has been associated with a decreased antibody response to tetanus and diphtheria toxoids, meningococcal, salmonella, and Hib vaccines. Interest in giving malaria drug therapy and prevention at the time of childhood immunizations has increased greatly following recent trials of intermittent preventive therapy during infancy (IPTi), stimulating this re-analysis of unpublished data. The effect of malaria chemoprophylaxis on vaccine response was studied following administration of measles vaccines and diphtheria-tetanus-whole cell pertussis (DTP) vaccines. METHODS: In 1975, six villages divided into two groups of children ≤74 months of age from Burkina Faso, were assigned to receive amodiaquine hydrochloride chemoprophylaxis (CH+) every two weeks for seven months or no chemoprophylaxis (CH-). After five months, children in each group received either one dose of measles or two doses of DTP vaccines. RESULTS: For recipients of the measles vaccine, the seroconversion rates in CH+ and CH- children, respectively, were 93% and 96% (P > 0.05). The seroresponse rates in CH+ and CH- children respectively, were 73% and 86% for diphtheria (P > 0.05) and 77% and 91% for tetanus toxoid (P > 0.05). In a subset analysis, in which only children who strictly adhered to chemoprophylaxis criteria were included, there were, likewise, no significant differences in seroconversion or seroresponse for measles, diphtheria, or tetanus vaccines (P > 0.05). While analysis for pertussis showed a 43% (CH+) and 67% (CH-) response (P < 0.05), analyses using logistic regression to control for sex, age, chemoprophylaxis, weight-for-height Z-score, and pre-vaccination geometric mean titer (GMT), demonstrated that chemoprophylaxis was not associated with a significantly different conversion rate following DTP and measles vaccines. Seven months of chemoprophylaxis decreased significantly the malaria IFA and ELISA GMTs in the CH+ group. CONCLUSION: Malaria chemoprophylaxis prior to vaccination in malaria endemic settings did not improve or impair immunogenicity of DTP and measles vaccines. This is the first human study to look at the association between malaria chemoprophylaxis and the serologic response to whole-cell pertussis vaccine
Integrating temperature-dependent life table data into insect life cycle model for predicting the potential distribution of Scapsipedus icipe Hugel & Tanga
A new edible cricket species from Kenya of the genus Scapsipedus (Scapsipedus icipe Hugel & Tanga) is described through this study. Temperature-dependent development, survival, reproductive and life table parameters of S. icipe was generated and integrated into advanced Insect Life Cycle Modeling software to describe relative S. icipe population increase and spatial spread based on nine constant temperature conditions. Findings provide first-time important information on the impact of temperature on the biology, establishment and spread of S. icipe across the Africa continent. The prospect of edible S. icipe production to become a new sector in food and feed industry is discussed.GREENiNSECT of DanidaNetherlands Organization for Scientific ResearchWOTRO Science for Global Development (NWO-WOTRO)Federal Ministry for Economic Cooperation and DevelopmentAustralian Centre for International Agricultural Research (ACIAR)BioInnovate Africa Programm
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