544 research outputs found
Pengembangan Pembelajaran Matematika Berbasis Tutor Sebaya Dengan It Pada Siswa Sd Negeri Kemasan I Serengan Surakarta Tahun 2016/2017
Mathematics is one of the main subjects in the K13 in elementary school. Math must be mastered by the students as early as possible in the face of changing circumstances and the ever-evolving technology. To transfer the necessary mathematics to students learning methods that interest. One of the methods is the appropriate method peer tutors. This study examines the mathematics teachers do this time and the development of peer tutoring based learning with IT in SDN Kemasan I Surakarta. The purpose of this study is to describe the mathematics before action research, determine eligibility based peer tutoring mathematics learning using IT, as well as test the effectiveness of peer tutoring based math learning using IT media. This study was conducted for students of class V. This study uses research methods research and development (R & D) which is a product development activities are effective for use. Do lesson planning, implementation, testing, and refinement. Further testing of the effectiveness of student learning during the implementation of peer tutoring program in a class by comparing the results of student achievement before and after participating in the peer tutoring program in the classroom. The results of this study occurred average value of student learning outcomes have also been increased initially 65.33, on the stages I to 71.25, and at what stage II in 76.62
Multiple uncontrolled conditions and blood pressure medication intensification: an observational study
Abstract Background Multiple uncontrolled medical conditions may act as competing demands for clinical decision making. We hypothesized that multiple uncontrolled cardiovascular risk factors would decrease blood pressure (BP) medication intensification among uncontrolled hypertensive patients. Methods We observed 946 encounters at two VA primary care clinics from May through August 2006. After each encounter, clinicians recorded BP medication intensification (BP medication was added or titrated). Demographic, clinical, and laboratory information were collected from the medical record. We examined BP medication intensification by presence and control of diabetes and/or hyperlipidemia. 'Uncontrolled' was defined as hemoglobin A1c ≥ for diabetes, BP ≥ 140/90 mmHg (≥ 130/80 mmHg if diabetes present) for hypertension, and low density lipoprotein cholesterol (LDL-c) ≥ 130 mg/dl (≥ 100 mg/dl if diabetes present) for hyperlipidemia. Hierarchical regression models accounted for patient clustering and adjusted medication intensification for age, systolic BP, and number of medications. Results Among 387 patients with uncontrolled hypertension, 51.4% had diabetes (25.3% were uncontrolled) and 73.4% had hyperlipidemia (22.7% were uncontrolled). The BP medication intensification rate was 34.9% overall, but higher in individuals with uncontrolled diabetes and uncontrolled hyperlipidemia: 52.8% overall and 70.6% if systolic BP ≥ 10 mmHg above goal. Intensification rates were lowest if diabetes or hyperlipidemia were controlled, lower than if diabetes or hyperlipidemia were not present. Multivariable adjustment yielded similar results. Conclusions The presence of uncontrolled diabetes and hyperlipidemia was associated with more guideline-concordant hypertension care, particularly if BP was far from goal. Efforts to understand and improve BP medication intensification in patients with controlled diabetes and/or hyperlipidemia are warranted.http://deepblue.lib.umich.edu/bitstream/2027.42/78266/1/1748-5908-5-55.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78266/2/1748-5908-5-55.pdfPeer Reviewe
Giant Anharmonic Phonon Scattering in PbTe
Understanding the microscopic processes affecting the bulk thermal
conductivity is crucial to develop more efficient thermoelectric materials.
PbTe is currently one of the leading thermoelectric materials, largely thanks
to its low thermal conductivity. However, the origin of this low thermal
conductivity in a simple rocksalt structure has so far been elusive. Using a
combination of inelastic neutron scattering measurements and first-principles
computations of the phonons, we identify a strong anharmonic coupling between
the ferroelectric transverse optic (TO) mode and the longitudinal acoustic (LA)
modes in PbTe. This interaction extends over a large portion of reciprocal
space, and directly affects the heat-carrying LA phonons. The LA-TO anharmonic
coupling is likely to play a central role in explaining the low thermal
conductivity of PbTe. The present results provide a microscopic picture of why
many good thermoelectric materials are found near a lattice instability of the
ferroelectric type
Effect of preoperative thoracic duct drainage on canine kidney transplantation
Chronic drainage of the thoracic duct to the esophagus was developed in dogs, and its efficacy in immunomodulation was tested using kidney transplantation. Compared to 9.7 days in the control, the mean animal survival was prolonged to 9.9 days, 17.8 days, and 18.5 days when TDD was applied preoperatively for 3 weeks, 6 weeks, and 9 weeks, respectively. Prolongation was significant after 6 weeks. Patency of the fistula was 93.5, 80.4, and 76.1% at respective weeks. Number of peripheral T-lymphocytes determined by a new monoclonal antibody diminished after 3 weeks. All animals were in normal health, requiring no special care for fluid, electrolyte, or protein replacement
Prognostic value of prostate circulating cells detection in prostate cancer patients: a prospective study
In clinically organ-confined prostate cancer patients, bloodstream tumour cell dissemination generally occurs, and may be enhanced by surgical prostate manipulation. To evaluate cancer-cell seeding impact upon patient recurrence-free survival, 155 patients were prospectively enrolled then followed. Here, 57 patients presented blood prostate cell shedding preoperatively and intraoperatively (group I). Of the 98 preoperatively negative patients, 53 (54%) remained negative (group II) and 45 (46%) became intraoperatively positive (group III). Median biological and clinical recurrence-free time was far shorter in group I (36.2 months, P<0.0001) than in group II (69.6 months) but did not significantly differ in group II and III (69.6 months vs 65.0). Such 5-year follow-up data show that preoperative circulating prostate cells are an independent prognosis factor of recurrence. Moreover, tumour handling induces cancer-cell seeding but surgical blood dissemination does not accelerate cancer evolution
EpCAM an immunotherapeutic target for gastrointestinal malignancy: current experience and future challenges
Despite advances in surgery and adjuvant regimes, gastrointestinal malignancy remains a major cause of neoplastic mortality. Immunotherapy is an emerging and now successful treatment modality for numerous cancers that relies on the manipulation of the immune system and its effector functions to eradicate tumour cells. The discovery that the pan-epithelial homotypic cell adhesion molecule EpCAM is differentially expressed on gastrointestinal tumours has made this a viable target for immunotherapy. Clinical trials using naked anti EpCAM antibody, immunoconjugates, anti-idiotypic and dendritic cell vaccines have met variable success. The murine IgG2a Edrecolomab was shown to reduce mortality and morbidity at a level slightly lower than treatment with 5FU and Levamisole when administered to patients with advanced colorectal carcinoma in a large randomised controlled trial. Fully human and trifunctional antibodies that specifically recruit CD3-positive lymphocytes are now being tested clinically in the treatment of minimal residual disease and ascites. Although clinical trials are in their infancy, the future may bring forth an EpCAM mediated approach for the effective activation and harnessing of the immune system to destroy a pathological aberrance that has otherwise largely escaped its attention
The sudden change phenomenon of quantum discord
Even if the parameters determining a system's state are varied smoothly, the
behavior of quantum correlations alike to quantum discord, and of its classical
counterparts, can be very peculiar, with the appearance of non-analyticities in
its rate of change. Here we review this sudden change phenomenon (SCP)
discussing some important points related to it: Its uncovering,
interpretations, and experimental verifications, its use in the context of the
emergence of the pointer basis in a quantum measurement process, its appearance
and universality under Markovian and non-Markovian dynamics, its theoretical
and experimental investigation in some other physical scenarios, and the
related phenomenon of double sudden change of trace distance discord. Several
open questions are identified, and we envisage that in answering them we will
gain significant further insight about the relation between the SCP and the
symmetry-geometric aspects of the quantum state space.Comment: Lectures on General Quantum Correlations and their Applications, F.
F. Fanchini, D. O. Soares Pinto, and G. Adesso (Eds.), Springer (2017), pp
309-33
Prevalence and determinants of child undernutrition and stunting in semiarid region of Brazil
OBJECTIVE : To analyze the evolution in the prevalence and determinants of malnutrition in children in the semiarid region of Brazil. METHODS : Data were collected from two cross-sectional population-based household surveys that used the same methodology. Clustering sampling was used to collect data from 8,000 families in CearĂĄ, Northeastern Brazil, for the years 1987 and 2007. Acute undernutrition was calculated as weight/age < -2 standard deviation (SD); stunting as height/age < -2 SD; wasting as weight/height < -2 SD. Data on biological and sociodemographic determinants were analyzed using hierarchical multivariate analyses based on a theoretical model. RESULTS : A sample of 4,513 and 1,533 children under three years of age, in 1987 and 2007, respectively, were included in the analyses. The prevalence of acute malnutrition was reduced by 60.0%, from 12.6% in 1987 to 4.7% in 2007, while prevalence of stunting was reduced by 50.0%, from 27.0% in 1987 to 13.0% in 2007. Prevalence of wasting changed little in the period. In 1987, socioeconomic and biological characteristics (family income, motherâs education, toilet and tap water availability, childrenâs medical consultation and hospitalization, age, sex and birth weight) were significantly associated with undernutrition, stunting and wasting. In 2007, the determinants of malnutrition were restricted to biological characteristics (age, sex and birth weight). Only one socioeconomic characteristic, toilet availability, remained associated with stunting. CONCLUSIONS : Socioeconomic development, along with health interventions, may have contributed to improvements in childrenâs nutritional status. Birth weight, especially extremely low weight (< 1,500 g), appears as the most important risk factor for early childhood malnutrition
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