78 research outputs found

    A New Method for Obtaining the Baryons Mass under the Killingbeck Plus Isotonic Oscillator Potentials

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    In this work, the spectrum of ground state and excited baryons (N, {\Delta}, , , and {\Omega} particles) has been investigated by using a non-relativistic quantum mechanics under the Killingbeck plus isotonic oscillator potentials. Using the Jacobi-coordinates, anzast method and generalized G\"ursey Radicati (GR) mass formula the three body wave equation is solved to calculate the different states of the considered baryons. A comparison between our calculations and the available experimental data shows that the position of the Roper resonances of the nucleon, the ground states and the excited multiplets up to three GeV are in general well reproduced. Also one can conclude that; the interaction between the quark constituents of baryon resonances could be described adequately by using the combination of Killingbeck and isotonic oscillator potentials form.Comment: arXiv admin note: text overlap with arXiv:nucl-th/0506032 by other author

    Baryon masses in a nonrelativistic model with the quantum isotonic oscillator potential

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    The nonrelativistic quark model and a new baryon mass formula have been applied to study the baryon octet and decuplet masses. To describe the quark-quark interacting forces inside baryons, a suitable phenomenological form of the potential and quantum isotonic oscillator potential have been proposed. A comparison between calculations reported in this study and the available experimental data is investigated. The description of the spectrum shows that the position of the Roper resonances of the nucleon, the ground states and the excited multiplets up to three GeV are in general well reproduced

    ASSESSMENT OF THE EFFICACY OF PROPRANOLOL AND DILTIAZEM ON THE INTENSITY, DURATION AND PERIODS OF PAIN IN THE ANGINA PATIENTS REFERRED TO THE HEART CLINIC OF THE SHAHREKORED UNIVERSITY OF MEDICAL SCIENCES

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    ASSESSMENT OF THE EFFICACY OF PROPRANOLOL AND DILTIAZEM ON THE INTENSITY, DURATION AND PERIODS OF PAIN IN THE ANGINA PATIENTS REFERRED TO THE HEART CLINIC OF THE SHAHREKORED UNIVERSITY OF MEDICAL SCIENCES KHaledi A1, Elahei N2,Moradi M3, Salehi SH4* Received: 7 Sep , 2013 Accepted: 16 Nov , 2013 Abstract Background & Aims: Ischemic heart disease is one of the most common, chronic and deadly diseases in the world. Ischemic heart disease treatment consists of ensuring the patient, its identification, eliminating risk factors, lifestyle changes and drug therapy. The study tries to compare the efficacy of propranolol and diltiazem on the intensity, duration and periods of pain in the angina patients referred to the heart clinic of Shahrekored University of Medical Sciences. Materials & Methods: In a cross sectional study 60 patients with stable angina were selected with convenience sampling. Initially after receiving exercise testing, and completing the questionnaire to determine angina class, the patients were randomly divided into A and B groups by using the questionnaire and related chart recording of physiological variables. Demographic characteristics, types of drugs, the number of angina attacks and the results of the stress test were registered. The patients were treated with 20 mg propranolol every 8 hours daily, and with 30 mg diltiazem for 6 weeks, and they were considered as Group A, and Group B respectively. The patients were examined by a cardiologist for 6 weeks. Inclusion criteria to the survey were typical angina pain, positive exercise test, patient satisfaction, and dwelling in the provincial capital. Exclusion criteria were negative exercise test, treated with cardiac drugs, drug complications, diabetes, severe ischemic attacks, and cutting off medication. Hospitalization data were recorded by a questionnaire, and the collected papers were analyzed by using SPSS statistical software. Results: The results showed that from the 60 stable angina patients in both groups of A, and B, 68.3 % were male, and 31.7 % were females. The most abundant minor pain, was angina pain, with 50% , and the least pain, was terrified angina pain with 10%. The most abundant Angina class was class 2 with 80%, and lowest was class 3 with 8.3%. There was a significant differences between the two groups of treatment concerning the drug’s effectiveness, number of attacks of pain, and the effect of pain. Fisher's exact test indicated that there was a significant difference between negative exercise test in the two groups. Conclusion: Although both Ayndral and diltiazem had an effective role on the quality of pain, number of attacks, period of pain in patients with stable angina, but this effect was more effective in diltiazem group. More investigations with bigger sample size are needed

    The immunomodulatory effect 1,25 (OH)2 D3 on TLR 2 and TLR4 expression on monocytes of patients with type II diabetes mellitus

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    Background: Recent studies have shown the immunomodulatory effect of vitamin D3 through down-regulation of Toll-like receptor (TLR) expression in human monocytes. In this study, the effects of vitamin D treatment on TLR2 and TLR4 expression on monocytes derived from type 2 diabetes was investigated.Materials and Methods: To assess the influence of vitamin D3 on expression of TLR2 and TLR4 on monocytes from patients with type II diabetes, peripheral blood sample was taken of 30 patients. Peripheral blood mononuclear cells (PBMCs) were isolated by density gradient centrifuge and then monocytes were isolated from these cells with using the magnetic activated cell sorting (MACS). To investigate the effect of vitamin D3 on the expression of TLR2 and TLR4, monocytes were cultured in the presence of vitamin D3 (10-9 M) for 48 hours. Then the expression of TLR2 and TLR4 was determined by Real-time PCR.Results: We found that vitamin D3 suppresses the mRNA expression of TLR2 and TLR4 in patients with type II diabetes. TLR2 and TLR4 expression in the patients exposed to vitamin D3 were significantly decreased in comparison with patients who were not treated with vitamin D3.Conclusion: It can be concluded that vitamin D3 supplements may be further analyzed as a therapeutic option by reducing TLR2 and TLR4 expression in patients with type II diabetes

    Antibiotic Resistance Profle in Relation to Phylogenetic Background in Escherichia coli Isolated From Fecal Samples of Healthy Ostrich

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    Background: E. coli is regarded as a reservoir for antibiotic resistance in foods of animal origin. E. coli can be categories into four main phylogenetic groups (A, B1, B2 and D). The commensal E. coli strains mostly are assigned to the phylo-groups A and B1. Objectives: The purposes of this study were to determine the phylogenetic group/subgroups and antibiotic resistance patterns of ostrich E. coli isolates in Iran. Materials and Methods: A total of 126 E. coli isolates were obtained from cloacae swabs of the healthy ostrich in Kerman, Iran. The E. coli isolates were confrmed using biochemical API 20E identifcation system. The confrmed isolates were studied to determine phylogenetic background by PCR. The isolates were tested for antibiotic resistance against 12 different antibiotic disk by disk diffusion method. Results: Phylotyping of E. coli isolates indicated that 74 isolates belonged to A, 27 isolates to B1, 7 isolates to B2, and 18 isolates to D groups. Also the isolates fell into six phylogenetic subgroups, including 34 isolates in A0, 40 isolates in A1, one isolate in B22, 6 isolates in B23, 11 isolates in D 1 and 7 isolates in subgroup D2. In the examined E. coli isolates, the maximum rate of resistance was against tetracycline, and the minimum rate of resistance was against amoxicillin. Twenty three antibiotic resistance patterns were detected among the isolates. The cefoxitin and tetracycline resistance pattern was the most prevalent in the isolates that belonged to phylo-group A. Conclusions: In conclusion, the result of the present study revealed a low frequency of antibiotic resistance in ostrich E. coli isolates. The antibiotic resistance patterns were in relation to A and D phylogenetic groups. Further studies are needed to better understand the distribution of phylogenetic groups in poultry isolates

    Relationship between thyroid stimulating hormone and metabolic syndrome in overweight/obese children

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    Background: Background: Obesity, especially central obesity is related to many endocrine abnormalities, such as thyroid dysfunctions. Elevated levels of thyroid stimulating hormone (TSH) is common in obese children, however, it is not clear if such condition is associated with increased cardiovascular risk factors. The study aimed to determine the association between levels of TSH in overweight and obese children with components of metabolic syndrome (Mets). Methods: The study sample included 197 overweight/obese 6-7 year old children in Tehran, Iran. Anthropometric (weight, waist circumference and height), metabolic (high-density lipoprotein cholesterol, triglycerides and fasting blood glucose) and hormonal (TSH) variables, as well as blood pressure were measured. Mets was defined according to Cook definition. Results: Totally, 20.3% and 79.7% of children were overweight and obese, respectively. Elevated levels of TSH were diagnosed in 10 subjects (5.1%), while Mets was seen in 35.4%. The most frequent component of Mets was abdominal obesity (72.5%). A weak positive correlation between BMI for age, Z scores and TSH level (r =0.11, P value= 0.123) was observed only in girls (r=0.2, P value= 0.034). TSH was not associated with components of Mets. Conclusion: Elevated TSH levels may be found in obese children; however, the association between TSH elevation and cardiovascular disease risk factors, including components of metabolic syndrome needs further investigation
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