4 research outputs found
Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma
The European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) was established 25 years ago with the goal to facilitate clinical trials and research collaborations in the field both within Europe and worldwide. Since its inception, much progress has been made whereby major improvements in outcomes have been achieved. In this Review, we describe the different diagnostic entities of non-Hodgkin lymphoma in children and young adults describing key features of each entity and outlining clinical achievements made in the context of the EICNHL framework. Furthermore, we provide an overview of advances in biopathology with an emphasis on the role of biological studies and how they have shaped available treatments. Finally, for each entity, we describe future goals, upcoming clinical trials, and highlight areas of research that require our focus going forward
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Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma.
The European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) was established 25 years ago with the goal to facilitate clinical trials and research collaborations in the field both within Europe and worldwide. Since its inception, much progress has been made whereby major improvements in outcomes have been achieved. In this Review, we describe the different diagnostic entities of non-Hodgkin lymphoma in children and young adults describing key features of each entity and outlining clinical achievements made in the context of the EICNHL framework. Furthermore, we provide an overview of advances in biopathology with an emphasis on the role of biological studies and how they have shaped available treatments. Finally, for each entity, we describe future goals, upcoming clinical trials, and highlight areas of research that require our focus going forward
Governing the âGolden Age of Infrastructureâ: Assessing Transparency Innovations in Philippine Infrastructure Development
Amidst rising infrastructure investment across the AsiaâPacific, glaring accountability deficits have raised questions about governmentsâ capacity to contain corruption in infrastructure development in the region. Recent developments in the Philippines, however, indicate the presence of challenges related to the ability of digitally enhanced transparency measures to bridge such accountability deficits. This article presents the shifting emphasis in transparency and accountability reforms related to Philippine infrastructure development beginning from the 1990s and assesses transparency innovations under the Duterte administration. While milestone measures such as the establishment of an electronic freedom of information (eFOI) platform have provided convenient access to public information, major hurdles remain in obtaining critical documents concerning infrastructure projects. As borne out in an exercise to request the feasibility studies of 48 flagship infrastructure projects, access to information is still obstructed by factors ranging from technical constraints, uneven service delivery, coordination failures, as well as active legal restrictions against the publicâs right to know