Esophageal motor abnormalities in scleroderma and related diseases

Esophageal motor activity was measured by intra-esophageal pressure recordings in 53 patients with scleroderma and 29 patients with other collagen diseases. The purpose of the study was to determine the relationship of motor abnormalities to esophageal symptoms, to compare the abnormalities in scleroderma with those in other collagen diseases, and to try to increase understanding of the responsible mechanism. Methacholine was given to 36 of the 53 patients with scleroderma to confirm that the Mecholyl test is negative in scleroderma and to see whether intraluminal pressure changes accompany the resulting improvement in esophageal emptying.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44360/1/10620_2005_Article_BF02233564.pd

Novel Approaches to Learning With Data

This video, from the 2021 Esri Education Summit, provides three different presentations about learning with data. In the first presentation, Steve Borders from Coastal Carolina University describes the South Carolina Healthy Communities Index and explores the visualization of health inequality using interactive maps and dashboards. ArcGIS, Business Analyst Online, student projects, and more are highlighted. In the second presentation, Chris Saladin from the University of Minnesota describes collaborative class projects with Survey123. A StoryMaps curriculum team, example Survey123 assignments, and project takeaways are explored. In the final presentation, Maria Brown from Stony Brook University explores the use of integrative maps for Bats of the World. Brown explores visualization problems in bat research, student solutions, the mapping process, data, and an interactive webmap. The video recording runs 46:34 minutes in length. Additional videos from the summit are available to view separately

Hybrid larch (Larix x eurolepis Henry): a good candidate for cadmium phytoremediation?

International audienceStudies related to phytoremediation by conifers are still at their beginning. Thus, we investigated the ability of a hybrid larch (Larix x eurolepis) to accumulate cadmium (Cd). One-month-old clonal plantlets grown in vitro were exposed for 1 week to a high Cd concentration (1.5 mM). No significant effect was observed on root and shoot biomass, root length, and needle number as a result of Cd treatment. Leaf photosynthetic pigment content and total soluble protein concentration in roots and shoots remained unchanged compared to control plantlets. Taken together, these results suggested that hybrid larch tolerated Cd in our conditions. The high Cd concentration in shoots (200 μg Cd gram(-1) dry weight) showed the good capacity of larch to translocate Cd and thus a potential use of this species for phytoremediation. Furthermore, under our conditions, phytochelatin biosynthesis pathway was slightly stimulated, suggesting that this pathway did not reach the threshold and/or another mechanism of Cd storage may be involved to explain larch tolerance to Cd

High concentration of cadmium induces AtPCS2 gene expression in Arabidopsis thaliana (L.) Heynh ecotype Wassilewskija seedlings

International audienceIn Arabidopsis thaliana, two genes encoding phytochelatin synthase (PCS; EC 2.3.2.15), AtPCS1 and AtPCS2, have been identified. Until now, only AtPCS1 was shown to play a role in response to Cd. To gain insight into the putative role of AtPCS2, three Cd concentrations (50, 100 and 200 μM) and long-term exposure (7 days) were tested on 1-week-old A. thaliana ecotype Wassilewskija (Ws) seedlings. Since 100 μM Cd did not alter seedling metabolism, as shown by unchanged total soluble protein and free proline contents, we investigated plantlet response to this concentration in addition to Cd accumulation. Seedlings accumulated Cd in roots and shoots. As phytochelatins and glutathione (GSH) contents increased in treated seedlings, we suggested that Cd might be translocated via the phytochelatin pathway. Specific enzymatic activities of γ-glutamylcysteine synthetase (GCS; EC 6.3.2.2), glutathione synthetase (GS; EC 6.3.2.3) and PCS were twice much more stimulated in shoots and roots after Cd exposure except GS that remained constant in shoots. As expression of genes encoding GCS and GS was unchanged in response to Cd, we suggested a regulation at translational or post-translational level. Surprisingly, AtPCS1 and AtPCS2 were differentially up-regulated after Cd treatment: AtPCS1 in shoots and AtPCS2 in whole plantlets. This last result suggests that PCS2 could be involved in plant response to high concentration of Cd in Ws ecotype and supports a putative role of PCS2, not redundant with PCS1, in a long-term response to Cd

La Presse musicale alternative

Fort de contributions internationales, le dossier de ce numéro de Volume ! est consacré à l’édition musicale alternative. Cette petite presse a explosé avec le mouvement punk et sa philosophie « do it yourself » et qui n’a cessé de croître depuis, servant d'empreinte identitaire, de ciment collectif, de bannière à tout un ensemble de subcultures musicales. Le numéro est illustré de couvertures de fanzines choisies par les auteurs des articles. This special issue of Volume ! is dedicated to the alternative musical press - fanzines. This press exploded with the punk movement and its "Do it yourself" philosophy, and has not stopped growing since. It serves as an identity imprint, a collective bond, the multiple banner for a whole set of musical subcultures. This issue is illustrated by fanzine covers chosen by the authors of the articles

La Presse musicale alternative

Fort de contributions internationales, le dossier de ce numéro de Volume ! est consacré à l’édition musicale alternative. Cette petite presse a explosé avec le mouvement punk et sa philosophie « do it yourself » et qui n’a cessé de croître depuis, servant d'empreinte identitaire, de ciment collectif, de bannière à tout un ensemble de subcultures musicales. Le numéro est illustré de couvertures de fanzines choisies par les auteurs des articles. This special issue of Volume ! is dedicated to the alternative musical press - fanzines. This press exploded with the punk movement and its "Do it yourself" philosophy, and has not stopped growing since. It serves as an identity imprint, a collective bond, the multiple banner for a whole set of musical subcultures. This issue is illustrated by fanzine covers chosen by the authors of the articles