Evaluation of inflammatuar response in hysterectomies: a retrospective study in Kocaeli, Turkey

Objectives: The authors aimed to detect the inflammatory marker changes in laparoscopic hysterectomy (LH) and abdominalhysterectomy (AH) and to determine whether oophorectomy affected the results.Material and methods: The patients who underwent LH and AH with or without oophorectomy between 2018 and2019 were identified as two groups. The records of patients were reviewed retrospectively. Preoperative and postoperativein the first 24 hours hematocrit (HCT), hemoglobin (HB), white blood cell (WBC), platelet-lymphocyte ratio (PLR), andneutrophil-lymphocyte ratio (NLR) values were compared.Results: WBC, NLR, and PLR were statistically increased, and HB and HCT were decreased in all groups in the postoperativeperiod. However, all changes were more prominent in the AH group than in the LH group. In other words, in the postoperativeperiod, there were fewer changes in the inflammatory markers WBC, NLR, and NLR in the LH group. Oophorectomydid not affect these results.Conclusions: LH, as in other laparoscopic operations, was associated with lower inflammatory response. The additionof oophorectomy did not increase inflammation in either AH or LH. Clinical Trials registration number is NCT04184765