ガッコウ キョウイク ニ オケル コドモ ノ セイメイ ケンコウ ノ イチヅケ ニ カンスル ケンキュウ ダイ3ポウ カッコウ ノ キョウイク モクヒョウ ト ノ カンレン オ チュウシン ニ

This study analysed the educational goals of various schools for the purpose of understanding the position of children\u27s lives and health etc., in school education. We chose 705 elementary, junior high, and high schools randomly throughout Japan, and received data on the educational goals of 221 of these schools (75 elementary, 70 junior high, and 76 high schools). The results of the survey are as follows: In elementary and junior high schools, each school\u27s educational goals tended to reflect the actual situation of the children, whereas in high schools, they tended to reflect the schools\u27 precepts and traditions. The contents of the educational goals could be classified into 25 items. In approximately 80% of the schools, mental health and physical health were rated as educational goals, whereas respect for life was low at 3.6% . The understanding and evaluation by other staff was high with regards to the stance of yogo teachers in terms of educational goals such as independence, but low in terms of humanity. It is important that yogo teachers continue to deepen their experience in order to make definite evaluations of activities within the school education that protect and nurture the children\u27s life and health, while appealing to the school as a whole

Infectious virus shedding duration reflects secretory IgA antibody response latency after SARS-CoV-2 infection

新型コロナウイルス排出と粘膜抗体の関係を解明 --呼吸器ウイルスのヒト間伝播を制御・予防する第一歩--. 京都大学プレスリリース. 2023-12-25.Articles: Infectious virus shedding duration reflects secretory IgA antibody response latency after SARS-CoV-2 infection. 京都大学プレスリリース. 2023-12-25.Infectious virus shedding from individuals infected with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is used to estimate human-to-human transmission risk. Control of SARS-CoV-2 transmission requires identifying the immune correlates that protect infectious virus shedding. Mucosal immunity prevents infection by SARS-CoV-2, which replicates in the respiratory epithelium and spreads rapidly to other hosts. However, whether mucosal immunity prevents the shedding of the infectious virus in SARS-CoV-2-infected individuals is unknown. We examined the relationship between viral RNA shedding dynamics, duration of infectious virus shedding, and mucosal antibody responses during SARS-CoV-2 infection. Anti-spike secretory IgA antibodies (S-IgA) reduced viral RNA load and infectivity more than anti-spike IgG/IgA antibodies in infected nasopharyngeal samples. Compared with the IgG/IgA response, the anti-spike S-IgA post-infection responses affected the viral RNA shedding dynamics and predicted the duration of infectious virus shedding regardless of the immune history. These findings highlight the importance of anti-spike S-IgA responses in individuals infected with SARS-CoV-2 for preventing infectious virus shedding and SARS-CoV-2 transmission. Developing medical countermeasures to shorten S-IgA response time may help control human-to-human transmission of SARS-CoV-2 infection and prevent future respiratory virus pandemics