Lipoatrophic diabetes. Report of a case

The female patient initially showed the acquired type of total lipoatrophy at about 8 years of age. At 12 years of age, the onset of diabetes mellitus was speculated from advanced pyodermia and dedentition. At 29 years of age, glucosuria was found, and she developed proteinuria, ascites, and pretibial edema. The physical examination revealed: hepatosplenomegaly, complete absence of subcutanous fat, cutaneous xanthomas, and emaciated facies with pronounced zygomatic arches. Diabetic retinopathy was revealed in the ophthalmological examination, and nephropathy was evident in renal biopsy specimens. She also had peripheral diabetic neuropathy. No adipose tissue was found in the mesenterium under peritoneoscopy. The hepatic biopsy specimen revealed advanced portal liver cirrhosis. Laboratory findings included: hyperlipidemia, elevation of BMR without evidence of hyperthyroidism, impaired renal function, and undetected anti-insulin antibodies and anti-insulin antibodies. Endocrinological examinations revealed normal value, except for an impaired hGH response in the arginine test. C-peptide immunoreactivity was high. Her condition was fairly well controlled by 140 units of insulin injection daily.</p

Sarcoidosis-associated hepatocellular carcinoma

Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma occurred within the liver, which was probably involved as a result of systemic sarcoidosis. A 57-year-old Japanese man had been followed up for 2 years because of diabetic nephropathy and sarcoidosis. On admission for pneumonia, imaging studies revealed an unexpected hepatic tumor. Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. The patient had no other apparent liver disease such as viral hepatitis, steatohepatitis, or primary biliary cirrhosis. Therefore, in the present case, sarcoidosis may be considered the probable background etiology for hepatocarcinogenesis

Clustering Properties of Low-Luminosity Star-Forming galaxies at z = 0.24 and 0.40 in the Subaru Deep Field

We present our analysis on the clustering properties of star-forming galaxies selected by narrow-band excesses in the Subaru Deep Field. Specifically we focus on Halpha emitting galaxies at z = 0.24 and z = 0.40 in the same field, to investigate possible evolutionary signatures of clustering properties of star-forming galaxies. Based on the analysis on 228 Halpha emitting galaxies with 39.8 < log L(Halpha) < 40.8 at z = 0.40, we find that their two-point correlation function is estimated as xi = (r/1.62^{+0.64}_{-0.50} Mpc)^{-1.84 +/- 0.08}. This is similar to that of Halpha emitting galaxies in the same Halpha luminosity range at z = 0.24, xi = (r/1.88^{+0.60}_{-0.49} Mpc)^{-1.89 +/- 0.07}. These correlation lengths are smaller than those for the brighter galaxy sample studied by Meneux et al. (2006) in the same redshift range. The evolution of correlation length between z = 0.24 and z = 0.40 is interpreted by the gravitational growth of the dark matter halos.Comment: 16 pages, 7 figures, PASJ, Vol.60, No.6, in pres

Scalability of spin FPGA: A Reconfigurable Architecture based on spin MOSFET

Scalability of Field Programmable Gate Array (FPGA) using spin MOSFET (spin FPGA) with magnetocurrent (MC) ratio in the range of 100% to 1000% is discussed for the first time. Area and speed of million-gate spin FPGA are numerically benchmarked with CMOS FPGA for 22nm, 32nm and 45nm technologies including 20% transistor size variation. We show that area is reduced and speed is increased in spin FPGA owing to the nonvolatile memory function of spin MOSFET.Comment: 3 pages, 7 figure