IN VITRO STUDY ON RELEASE OF BIOACTIVE ANTIMICROBIAL COMPOUNDS FROM DAIRY PRODUCTS BY CERTAIN PROMISING PROBIOTIC LACTOBACILLUS STRAINS

Objective: The antimicrobial activity and Probiotic properties of Lactobacillus species were evaluated. The antimicrobial compound of potent antimicrobial probiotic Lactobacillus was purified by column chromatography and its nature and stability were determined.Methods: This investigation was performed with few Lactobacillus strains of ATCC and MTCC along with certain strains isolated from different dairy sources. They were evaluated for their probiotics properties (acid tolerance, bile tolerance, bile salt hydrolase activity, cell autoaggregation, cell surface hydrophobicity and haemolytic behaviour). Agar well diffusion method was used to screen their potency to release bioactive compound against several pathogens. This potent antimicrobial compound was purified by chromatography as well as its molecular mass was estimated by following SDS-PAGE. Finally, the stability of the compound was determined against various ranges of temperature and pH.Results: Among all Lactobacillus strains, R1 was found to be a potent probiotic strain as well as cell free supernatant (CFS) of R1 showed more strong antagonistic effect against most of the pathogens. Carbohydrate fermentation and physiological characterization of strain R1 matched with Lactobacillus fermentum as per Bergey's manual of systematic bacteriology. The molecular mass of the purified fraction was estimated at approximately 25 kDa and could be stable after heat treatment of 100 °C for 30 min and pH range of 4.5-7.0Conclusion: R1 showed highest antimicrobial activity while it has been found as Lactobacillus fermentum. It is due to the release of a bioactive compound having a molecular mass of 25 kDa.Â

Quality of Schooling: Child Quantity-Quality Tradeoff, Technological Progress and Economic Growth

An overlapping generations version of an R&D-based growth model `a la Diamond (1965) and Jones (1995) is built to examine how improvement in quality of schooling impact technical progress and longrun economic growth of an economy by influencing fertility and education decisions at household level. The results indicate that improvement in schooling quality triggers a child quantity-quality trade-off at household level when quality of schooling exceeds an endogenously determined threshold. At the household level, parents invest more in education of children and have lesser number of children in response to improvement in quality of schooling. This micro-level tradeoff has two opposing effects on aggregate human capital accumulation at macro level. Higher investment in education of a child stimulates the accumulation of human capital which fosters technical progress but the simultaneous decline in fertility rate reduces the total factor productivity growth and economic growth by contracting the pool of available researchers. The first effect prevails over latter only when quality of schooling is higher than the threshol

Impact of strengthening Intellectual Property Rights Regime on income inequality: An econometric analysis

The theory predicts that IPRs tend to raise income inequality by generating a more skewed distribution of wages. Stronger IPRs increase the demand for skilled labor force as it raises the return on R&D activities. This causes a relative increase in skilled labor wages, creating a wage bias in favor of skilled labor against unskilled labor, thus aggravating income inequality within a country. Using dynamic panel data techniques and a sample of 55 countries over 1980-2011, we examine the impact of strengthening Intellectual Property Rights (IPRs) on income distribution of a country. Our results indicate that the impact of IPRs on income distribution is contingent upon level of development of a country.Strengthening of IPRs increases income inequality in countries with higher level of development having higher ability to innovate

Quality of Schooling: Child Quantity-Quality Tradeoff, Technological Progress and Economic Growth

An overlapping generations version of an R&D-based growth model `a la Diamond (1965) and Jones (1995) is built to examine how improvement in quality of schooling impact technical progress and longrun economic growth of an economy by influencing fertility and education decisions at household level. The results indicate that improvement in schooling quality triggers a child quantity-quality trade-off at household level when quality of schooling exceeds an endogenously determined threshold. At the household level, parents invest more in education of children and have lesser number of children in response to improvement in quality of schooling. This micro-level tradeoff has two opposing effects on aggregate human capital accumulation at macro level. Higher investment in education of a child stimulates the accumulation of human capital which fosters technical progress but the simultaneous decline in fertility rate reduces the total factor productivity growth and economic growth by contracting the pool of available researchers. The first effect prevails over latter only when quality of schooling is higher than the threshol

Impact of strengthening Intellectual Property Rights Regime on income inequality: An econometric analysis

The theory predicts that IPRs tend to raise income inequality by generating a more skewed distribution of wages. Stronger IPRs increase the demand for skilled labor force as it raises the return on R&D activities. This causes a relative increase in skilled labor wages, creating a wage bias in favor of skilled labor against unskilled labor, thus aggravating income inequality within a country. Using dynamic panel data techniques and a sample of 60 countries over 1980-2011, we examine the impact of strengthening Intellectual Property Rights (IPRs) on income distribution of a country. Our results indicate that contrary to findings of previous research, strengthening of IPRs reduces income disparities within a country

Impact of strengthening Intellectual Property Rights Regime on income inequality: An econometric analysis

This paper examines the impact of strengthening Intellectual Property Rights (IPRs) on within-country income inequality for a cross-section of 65 developed and developing countries for the time period 1995-2009.Our results indicate that strengthening of IPRs has led to an increase in income inequality in WTO-member developing countries after they started modifying their national IPR regimes to conform to the TRIPs requirements. IPRs tend to raise income inequality by generating a more skewed distribution of wages. Stronger IPRs increase the demand for skilled labor force as it raises the return on R&D activities. This causes a relative increase in skilled labor wages, creating a wage bias in favor of skilled labor against unskilled labor, thus aggravating income inequality within a developing country. Moreover, the effect on inequality is more pronounced for developing countries that are experiencing higher per capita GDP growth rates. As for the developed countries included in the sample, the analysis seems to suggest that IPRs have led to a decline in income inequality over the study period

Impact of strengthening Intellectual Property Rights Regime on income inequality: An econometric analysis

The theory predicts that IPRs tend to raise income inequality by generating a more skewed distribution of wages. Stronger IPRs increase the demand for skilled labor force as it raises the return on R&D activities. This causes a relative increase in skilled labor wages, creating a wage bias in favor of skilled labor against unskilled labor, thus aggravating income inequality within a country. Using dynamic panel data techniques and a sample of 60 countries over 1980-2011, we examine the impact of strengthening Intellectual Property Rights (IPRs) on income distribution of a country. Our results indicate that contrary to findings of previous research, strengthening of IPRs reduces income disparities within a country

Quality of Schooling: Child Quantity-Quality Tradeoff, Technological Progress and Economic Growth

An overlapping generations version of an R&D-based growth model `a la Diamond (1965) and Jones (1995) is built to examine how improvement in quality of schooling impact technical progress and longrun economic growth of an economy by influencing fertility and education decisions at household level. The results indicate that improvement in schooling quality triggers a child quantity-quality trade-off at household level when quality of schooling exceeds an endogenously determined threshold. At the household level, parents invest more in education of children and have lesser number of children in response to improvement in quality of schooling. This micro-level tradeoff has two opposing effects on aggregate human capital accumulation at macro level. Higher investment in education of a child stimulates the accumulation of human capital which fosters technical progress but the simultaneous decline in fertility rate reduces the total factor productivity growth and economic growth by contracting the pool of available researchers. The first effect prevails over latter only when quality of schooling is higher than the threshol