Aqueous 2-methoxyethanol Reaction media: Synthesis of some 4,5-dihydro-pyrazole-1-carbaldehyde derivative

A novel N-formyl-2-pyrazoline derivative was synthesized by reaction of an α,β- unsaturated ketone with hydrazine hydrate and formic acid in aqueous 2-methoxyethanol reaction media. The Clean reaction conditions, simple workup procedure and short reaction time giving high yields of product are notable advantages of method. The structure of the title compound was established by IR, 1H NMR, 13C NMR and analytical data.

Synthesis and antibacterial activity of some new schiff bases and 2-Azetidinones containing iodohyydroxy biphenyl moiety

2-Hydroxy-5-phenylbenzaldehyde on iodination yielded 2-Hydroxy-3-iodo-5-phenylbenzaldehyde. This aldehyde on facile condensation with substituted aromatic amines in presence of catalytic amount of acetic acid to afford new series of Schiff bases. Further these Schiff bases on cyclocondensation reaction with chloroacetyl chloride afforded a biologically active 2-azetidinones derivatives. The structure of newly synthesized compounds characterized on the basis of elemental analysis and spectral data. The compounds prepared were tested against Xanthomonas citri, Escherichia coli, Erwinia carotovora and Bacillus subtilis. Some of these compounds showed potential antibacterial activity

TREATMENT OF HYPOTHYROIDISM IS IMPORTANT IN TREATING BIPOLAR AFFECTIVE DISORDER

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ARTIFICIAL PANCREAS SYSTEM : AN EFFECTIVE APPROACH FOR TREATMENT OF DIABETIC COMPLICATIONS (DIABETIC NEPHROPATHY)

Diabetes mellitus along with diabetic complication (diabetic nephropathy) is well documented. There are few studies regarding Artificial pancreas treatment, which is the only FDA approved treatment for safe and effective way to stop and to  reverse  the  chronic  life  shortening  complications  of  diabetes. Here our main motto is to report such a case, who was presented with diabetic complication (particularly diabetic nephropathy) and undergoing treatment with artificial pancreatic system & to explain briefly with what mechanism does the artificial pancreatic system is effective in treatment or controlling the diabetic complications. Key words : Diabetes mellitus, diabetic nephropathy, artificial pancreas treatment