Formulation and evaluation of floating bioadhesive Doxofylline tablets

In the present work, an attempt has been made to develop gastro retentive floating tablets of Doxofylline .HPMC K4M and carbopol were used as controlled release polymers. All the formulations were prepared by direct compression method on 12 station rotary tablet punching machine. The blend of all the formulations showed god flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. FH 5 was the best optimized floating formulation because it released drug completely in 12hrs.It was also observed that the increasing concentration of polymers had a retarding effect on the drug release from the polymer matrices

Surgical management of traumatic crop fistula in a hen

Abstract: A case of traumatic crop fistula in a one year old hen and its successful surgical management has been reported

Thyroid hormone profile in per1transplant period in live donor kidney transplantation

Chronic renal failure, characterised by two factors acting in opposite directions with respect to the serum thyroid hormone levels was chosen for the study. Healthy controls, donors undergoing nephrectomy and renal transplant recipients were studied. In transplant recipients, presurgical levels of total thyroxine(TT4),free triiodothyronine(FT3) and free thyroxine(FT4) were lower than controls, and immediately after the release of arterial clamps, there was an upsurge of total triiodothyronine (TT3),TT4, FT3 and FT4 due to administered and/or endogeneously secreted catecholamines. The levels of the 7th day were comparable to the presurgical levels. The changes observed in donors and recipients were similar indicating that the hormonal changes observed are mostly due to surgical stress. Recovery in the hormonal status did not start in the first week of posttransplant period

A SEMIAUTOMATIC APPROACH FOR GENERATION OF SITE MODELS FROM CARTOSAT-2 MULTIVIEW IMAGES

In the last decade there has been a paradigm shift in creating, viewing and utilizing geospatial data for planning, navigation and traffic management of urban areas. Realistic, three-dimensional information is preferred over conventional two dimensional maps. The paper describes objectives, methodology and results of an operational system being developed for generation of site model from Cartosat-2 multiview images. The system is designed to work in operational mode with varying level of manual interactivity. A rigorous physical sensor model based on collinearity condition models the "step n stare" mode of image acquisition of the satellite. The relative orientation of the overlapping images is achieved using coplanarity condition and conjugate points. A procedure is developed to perform digitization in mono and stereo modes. A technique for refining manually digitized boundaries is developed. The conjugate points are generated by establishing a correspondence between the points obtained on refined edges to analogous points on the images obtained with view angles ±26 deg. It is achieved through geometrically constrained image matching method. The results are shown for a portion of multi-view images of Washington City obtained from Cartosat-2. The scheme is generic to accept very high resolution stereo images from other satellites as input

High burn-up issues in fast breeder reactor fuels and structural materials

Fast breeder reactors (FBR) are essential to enhance the share of nuclear power to meet the growing energy demands in India. For economic viability and sustainability of nuclear power, there is urgent need to achieve higher fuel burn-up so as to reduce the fuel cycle cost and supply power at competitive rates. Indian energy scenario demands development of high burn-up and high breeding capable fuels working with high safety and performance levels typical of FBRs. However, this poses many challenges in the development of advanced fuels as well as structural materials which can cope up with the rigorous environment in fast reactors. Prospective fuels for FBRs include mixed oxide, carbide, nitride and metallic fuels. Choice of core structural materials range from the conventional austenitic stainless steel to ferritic steels and oxide dispersion strengthened (ODS) steels. Various issues limiting the achievable burn-up in fuels and structural materials of fast breeder reactors are discussed in this paper