6 research outputs found

    A study of the association between cognitive abilities and dietary intake in young women

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    Background: Cognitive abilities comprise activities that relate to receiving and responding to information from the environment, internal processing, making complex decisions, and then responding to this in the context of behavior. Aim: The current study investigated the association between dietary intake and seven aspects of cognitive abilities among healthy young women. Methods: The study was carried out among 182 women aged 18–25 years. A valid and reliable food frequency questionnaire containing 65 food items was used to estimate dietary intake. Neuropsychological function and cognitive abilities of participants were determined using standard questionnaires. Results: Significant differences were found in depression, anxiety, stress, physical, and mental health-related quality of life as well as daytime sleepiness for the participants in different quartiles of cognitive abilities score (p<0.05). Participants in the fourth quartile of cognitive abilities score consumed significantly higher energy, carbohydrate, protein, calcium, iron, zinc, vitamin A, thiamin, and riboflavin compared to those in the lowest quartile (p<0.05). There were strong correlations between total cognitive abilities score and dietary sodium, calcium, phosphorus, and thiamin (p<0.05). Using stepwise multiple linear regression analysis, iron and thiamin were statistically significant factors for the prediction of cognitive abilities. Conclusions: These findings demonstrate that neurocognitive function is related to dietary macro and micronutrients including energy, carbohydrate, protein, calcium, iron, zinc, vitamin A, thiamin, and riboflavin on cognitive performance among young women without memory deficit

    Effect of Elaeagnus Angustifolia extract on in vitro wound healing of human dermal fibroblast cells

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    Abstract Aim The purpose of this study was to determine the impact of Elaeagnus Angustifolia extract (EA) on human dermal fibroblast (HDF) survival, migration, and wound healing-related genes. Methods After preparing the hydroalcoholic extract of EA, MTT and scratch tests were used to determine the effect of EA on the viability and migration of HDFs. In addition, the quantitative polymerase chain reaction (q-PCR) was conducted to evaluate the impact of EA on the expression of wound healing-related genes in HDFs. Result According to the MTT test, a nontoxic concentration of EA (100 µg/ml) was obtained for further investigations. The scratch test results demonstrated that EA improved HDFs’ capacity to migrate when compared to the control group. Additionally, q-PCR results revealed that EA could significantly increase wound healing-related genes (VEGF-A, HLA-G5, and IL-6) in comparison with the control group. Conclusions The EA could have a significant impact on the viability and migration of HDFs. Also, EA increased the expression of wound healing-related genes

    Effect of curcumin on inflammatory biomarkers and iron profile in patients with premenstrual syndrome and dysmenorrhea: A randomized controlled trial

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    Abstract Premenstrual syndrome (PMS) and primary dysmenorrhea are common gynecological problems and inflammation may have a role in their etiology. Curcumin is a polyphenolic natural product for which there is increasing evidence of anti‐inflammatory and iron chelation effects. This study assessed the effects of curcumin on inflammatory biomarkers and iron profile in young women with PMS and dysmenorrhea. A sample of 76 patients was included in this triple‐blind, placebo‐controlled clinical trial. Participants were randomly allocated to curcumin (n = 38) and control groups (n = 38). Each participant received one capsule (500 mg of curcuminoid+ piperine, or placebo) daily, from 7 days before until 3 days after menstruation for three consecutive menstrual cycles. Serum iron, ferritin, total iron‐binding capacity (TIBC) and high‐sensitivity C‐reactive protein (hsCRP), as well as white blood cell, lymphocyte, neutrophil, platelet counts, mean platelet volume (MPV) and red blood cell distribution width (RDW), were quantified. Neutrophil: lymphocyte ratio (NLR), platelet: lymphocyte ratio (PLR), and RDW: platelet ratio (RPR) were also calculated. Curcumin significantly decreased the median (interquartile range) serum levels of hsCRP [from 0.30 mg/L (0.0–1.10) to 0.20 mg/L (0.0–1.3); p = 0.041] compared with placebo, but did not show any difference for neutrophil, RDW, MPV, NLR, PLR and RPR values (p > 0.05). The treatment schedule was well‐tolerated, and none of markers of iron metabolism statistically changed after the intervention in the curcumin group (p > 0.05). Curcumin supplementation may have positive effects on serum hsCRP, a marker of inflammation, with no any changes on iron homeostasis in healthy women with PMS and dysmenorrhea

    The association between adherence to a dietary approaches to stop hypertension (DASH) diet and neuro-psychological function in young women

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    Abstract Background The adherence to a Dietary Approaches to Stop Hypertension (DASH) diet may have a bidirectional relationship with mental wellbeing. We aimed to evaluate the association between compliance with a DASH diet and neuro-psychological function in young women. Methods In this cross-sectional study, a total of 181 girls aged between 18 and 25 years were recruited. The dietary intakes of study participants were evaluated using a valid and reliable food frequency questionnaire (FFQ) containing 65 food items. Neuropsychological function of participants was evaluated using standard questionnaires. Results As may be expected, individuals in the highest tertile (T3) of adherence to DASH diet (highest adherence) were found to consume more folate, fruits, vegetables, low fat dairy, nuts, legume, and seed, less sweetened beverage and sodium, compared to the participants in the lowest tertile (T1, lowest adherence). There was a significant negative correlation between cognitive function and consumption of red and processed meat (r = − 0.168; p < 0.05); quality of life score with dietary sodium (r = − 0.151; p < 0.01) and depression score with dietary vegetables (r = − 0.174; p < 0.05). In multivariate multinomial logistic regression analyses adjusted for age, BMI and energy intake, adherence to a DASH-style diet was associated with a lower stress score (OR = 0.70; 95%CI: 0.34–1.47, P = 0.067; T3 vs. T1) and difficulty with sleep initiation (OR = 0.46; 95%CI: 0.21–1.00, P = 0.017; T3 vs. T1). Conclusion Adherence to a DASH diet may be associated with reduced stress and difficulty with initiating sleep
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