Effects of Exposure to WI-FI Signals (2.45 GHz) on Serum Oxidative Stress and Single Strand DNA Breaks in Peripheral Blood Lymphocytes of Mice

Introduction: Use of wireless devices have been increasing during the last three decades in the world. Health risks caused by exposure to these appliances has become a public concern. The purpose of this study was to investigate the effects of exposure to Wi-Fi on DNA breaks and oxidative stress parameters. Methods:16 male mice divided in 2 groups; experimental (exposed) (n=8) and the control groups (n=8). While the control group was kept not exposed to the signals the experimental group was exposed to 2.45 GHz Wi-Fi signal GHz, for 8h/21 day; Single strand DNA breaks in lymphocytes were determined by using the Alkaline Comet Assay (before and after the exposure period). Oxidative stress parameters, including, catalase activity, PON1 activity, and TAC were measured (before and after the exposure period). Results: In the exposed group, it was observed an increase in single-stranded DNA break; decrease in PON1 enzyme activity also increase the catalase activity compared to before exposure to wi-fi,  but TAC was not significantly different. While in the control group, none of the indicators measured at the end of the study there was no significant difference compared to 21 days ago. Conclusion: The findings of the present study show that Wi-Fi exposure can increase oxidative stress and the strand DNA break