Clinical and Urodynamic results of the Argus T® sling in moderate and severe male stress urinary incontinence after radical prostatectomy – a 5 year prospective study.

ABSTRACT Purpose: Sling as a therapeutic option for male stress urinary incontinence (SUI) has been reviewed in the last two decades, as it is a relatively simpliest surgery compared to artificial urinary sphincter and has the ability to modulate urethral compression. This study aims to evaluate the efficacy, rate of complications, quality of life and the effects on bladder emptying of the Argus T® compressive and ajustable sling in moderate and severe male SUI treatment. Materials and Methods: Men eligible for stress urinary incontinence treatment after radical prostatectomy were recruited and prospectively evaluated, from March 2010 to November 2016. It was selected outpatient men with moderate and severe SUI, after 12 months of radical prostatectomy, who have failed conservative treatment. All patients had a complete clinical and urodynamic pre and post treatment evaluation, by means of clinical history, physical examination, urine culture, 1-hour pad test and ICIq-SF questionnaire. The UDS was performed after 12, 18 and 24 months postoperatively. Results: Thirty-seven men underwent sling surgery, 19 patients (51.4%) with moderate and 18 (48.6%) with severe SUI. The minimum follow-up time was 5 years. Overall, we had a success rate of 56.7% at 60 months follow-up. After surgery, we did not observe significant changes in the urodynamic parameters evaluated during the follow-up. No patient had urodynamic bladder outlet obstruction (BOO) after sling implantation. Readjustment of the Argus T® sling was performed in 16 (41%) of the patients and 51% of the patients reported some adverse event. Conclusion: We demonstrate a long-term efficacy and safety of Sling Argus T® as an alternative to moderate and severe male SUI treatment. Furthermore, in our study bulbar urethra compression does not lead to bladder outlet obstruction

Polymer Characterization by GLC: Influence of Polymer Structure (Polybutadienes)

Proceedings (senza ISBN) del Congresso \u201cFourth Asian Chemical Congress\u201d, Pechino (CN), 26-30 agosto 1991 The infinite dilution activity coefficient of a solvent in a polymer is a thermodynamic property which can given useful information about the interactions between the components. This property can be determined by inverse gas chromatography, which enables to obtain reliable and accurate data in a relatively short time. In this work activity coefficients at infinite dilution of various solvents, representative of the different classes of organic compounds, are determined in different polybutadienes. The polymers were well characterized on the basis of structure and molecular weight. The influence of structure and of molecular weight of the polymer on the compatibility with the solvents is pointed out. Comparison with available data obtained by different authors in similar polymers is reported. The results are qualitatively interpreted by using the Perturbed Hard Chain E0S developed by Cottermann and Prausnitz

Solvent-Polymer Interactions in Polybutadienes

Infinite-dilution activity coefficients of 26 solvents in three polybutadienes were determined by inverse gas chromatography in the temperature range 40-100\ub0C. The polybutadienes have well-characterized structure and different molecular weights. The data are useful for the development of thermodynamic models for polymer-solvent interaction and for characterization. The results were fitted to the PHCT equation of state. The data indicate that activity coefficients depend on polymer molecular weight and structure

Infinite Dilution Activity Coefficients of Aromatic and Aliphatic Ethers

Activity coefficients at infinite dilution of several ethers and organics in different solvents were measured by gas-liquid chromatography. Tetrahydrofurane, anisole, diethyl, dipropyl and dibutyl ethers, n-pentane, n-hexane, methanol, chloroform and 1-chloropentane, were studied. The data were compared, where possible, with infinite dilution activity coefficients from the literature. The UNIFAC model was used to correlate the experimental data. Two definitions of the ether group were considered for anisole (methyl-phenyl-ether) the classical CH2O and an aromatic ACOCH2 group. Binary and ternary vapour-liquid equilibria of anisole with several organic compounds at finite concentrations were predicted with the parameters obtained from the infinite dilution data. The introduction of the ACOCH2 group does not improve predictions on these systems

Free radical production by azomethine H: Effects on pancreatic and hepatic tissues

The antimalarial properties of azomethine H represent the basis for its use as a chemotherapeutic agent. This work was carried out in order to verify the biological side effects of azomethine H and to clarify the contribution of reactive oxygen species (ROS) in this process. It was shown that azomethine H increased serum activities of amylase, alanine transaminase (ALT) and the TEARS concentrations, in rats. No changes were observed in glutathione peroxidase and catalase activities. The drug-induced tissue damage might be due to superoxide radicals (O-2(.-)), since Cu-Zn superoxide dismutase activities were increased by azomethine I-I treatment. This study allows tentative conclusions to be drawn regarding which reactive oxygen metabolites play a role in azomethine H activity. We concluded that (O-2(.-)) maybe produced as a mediator of azomethine H action