Trading app analyzer using implanted sensing technique in IoT via blockchain-based networks

Handheld devices equipped with sophisticated sensors enabling data collection as well as remote monitoring would lay the groundwork for one low-cost data trading approach. This data, for example, could be linked to contaminants and greenhouse emissions and then used to assess the limitations of current regulatory requirements. On a larger scale, the current IoT data trade method relies on a centralised third-party organisation to regulate among data producers and users, which is ineffective and unsafe. These decentralised solutions based on block chain technology, on the other hand, allow data exchange while guaranteeing integrity, confidentiality, and anonymity.  However, leading to a lack of understanding of process efficiency between retailers and buyers, there is a significant gap in assessing data trading procedures in IoT. We propose a paradigm for IoT-based data trade known as the Internet of Things and the blockchain network, that is intended to allow significant environmental monitoring and is influenced through the knowledge gap. We can examine the efficacy of transmission of three fundamental IoT trade protocol connections with respect to delay and power usage. These protocols model and analysis serve as a baseline for IoT data exchange solution

Nitric oxide and cancer: a review

Nitric oxide (NO), is a ubiquitous, water soluble, free radical gas, which plays key role in various physiological as well as pathological processes. Over past decades, NO has emerged as a molecule of interest in carcinogenesis and tumor growth progression. However, there is considerable controversy and confusion in understanding its role in cancer biology. It is said to have both tumoricidal as well as tumor promoting effects which depend on its timing, location, and concentration. NO has been suggested to modulate different cancer-related events including angiogenesis, apoptosis, cell cycle, invasion, and metastasis. On the other hand, it is also emerging as a potential anti-oncogenic agent. Strategies for manipulating in vivo production and exogenous delivery of this molecule for therapeutic gain are being investigated. However, further validation and experimental/clinical trials are required for development of novel strategies based on NO for cancer treatment and prevention. This review discusses the range of actions of NO in cancer by performing an online MEDLINE search using relevant search terms and a review of the literature. Various mechanisms by which NO acts in different cancers such as breast, cervical, gastric,colorectal, and head and neck cancers are addressed. It also offers an insight into the dichotomous nature of NO and discusses its novel therapeutic applications for cancer prevention and treatment