2,403 research outputs found

    GIS-enabled Spatial Analysis and Modeling of Geotechnical Soil Properties for Seismic Risk Assessment of Levee Systems.

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    Flood protection systems are complex, interconnected engineered systems, where failure at one location means the failure of the entire system. Earthen levees, the systems’ major component, are at risk from many causes of failure including seepage, erosion and instability due to seismic loading, yet there are currently no guidelines available for the seismic design of levees. Levees stretch for long distances and are formed through various geologic processes and human activities over time, however information regarding soil properties is collected only at limited point locations and varies significantly both laterally and with depth. Levee vulnerability analyses are currently performed only at locations with known soil properties. Prediction of levee performance in locations where no soil data is available becomes a limitation for system risk assessment studies. A simplified methodology is proposed to predict soil variability in riverine geologic environments for the seismic risk assessment of earthen levee systems. A key step in this methodology is to provide a continuous characterization of soil conditions throughout the system. The proposed model correlates soil properties to preselected regional variables and is implemented, using geostatistical kriging, in a Geographic Information Systems (GIS) environment. GIS was crucial in this research and proved to be the appropriate platform for input, manipulation, analysis, and output presentation of spatial and non-spatial data. Correlation relationships between soil strength parameters and geological and river geometry factors are presented for a pilot study area in California. Global observations that apply across the study area included the increasing trend of shear strength, Su, with increasing distance from the river, and decreasing trend of Su with increasing river Sinuosity Index levels. Only local trends were observed in the relation of friction angle, ϕ, with Sinuosity Index, as well as in the relation of Su and ϕ with geological formations. The proposed methodology also includes steps for seismic response analysis of levee segments, and flood scenarios in protected areas. Since seismic response of earthen structures is controlled primarily by input ground motions, a methodology for selecting ground motions based on their mean period, Tm, for liquefaction triggering assessment of levees is also developed.Ph.D.Civil EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/91571/1/msaadi_1.pd

    Idiopathic intracranial hypertension in pregnancy: about a rare case

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    In this work, study report the case of a 23-year-old primigravidae, in whom an idiopathic intracranial hypertension (IIH), formerly called pseudotumor cerebri, was diagnosed in the first trimester with visual field impairment, the management of which was similar to cases of benign intracranial hypertension in the general population. The parturient put under medical treatment with ophthalmological and obstetrical follow-up until 39 weeks of amenorrhea where she was cesarized for rescue of the visual prognosis. The objective of this work is to elucidate this pathology, caused by a defect of reabsorption of the CSF by the arachnoid plexus. The diagnosis is retained after elimination by radio-biological exploration of an infectious, tumor or traumatic etiology. Idiopathic intracranial hypertension has no impact on the evolution of pregnancy. In addition, the choice of delivery route is dependent on the patient's visual prognosis being brought into play

    Partial hydatidiform mole evolving into metastatic trophoblastic tumor: case report

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    Partial hydatidiform mole can evolve into a metastatic trophoblastic tumor. A 36-year-old, multiparous woman, pregnant with a 22-week embryonic hydatidiform mole, having spontaneously expelled. Histopathological examination showed a non-invasive partial mole. During biological monitoring, a trophoblastic tumor was diagnosed with pulmonary metastasis on CT-scan and myometrial invasion by MRI. Authors opted for a monochemotherapy with a good evolution. The potential risk of malignant transformation of the partial hydatidiform mole requires an adequate therapeutic strategy with strict monitoring

    Molecular Characterization of Restriction Endonuclease Extracted from Local E.coli Isolate

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    An endonucleases enzyme named EcoRHI has been purified partially from one of pathogenic E.coli isolate about 87-fold with endonuclease recovery about 12.6% . The purification steps included ammonium sulfate precipitation with 50% saturation ratio, and the enzymatic solution reclaimed it through Sephadex G-100 column .The SDS-PAGE analysis that showed molecular weight of EcoRHI enzyme is 45 KDa. The purified endonuclease was able to digest λ-DNA into two fragments

    Gynandroblastoma: a rare case report of ovarian sex cord tumour

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    Gynandroblastoma is an extremely rare ovarian sex cord tumor with malignant potential. An 61-year-old woman, menopausic, consulted for an abdominal pelvic mass. a latero-uterine mass measuring 27.8 cm in diameter showed a predominantly cystic pattern with a partial solid component. A unilateral adnexectomy was performed. A histopathological examination showed gynandroblastoma composed of juvenile granulosa and Sertoli-Leydig cells, chirurgical treatment was completed by total hysterectomy with right adnexectomy, omentectomy with no proof of malignant cells. We opted for a close observation without adjuvanted chemotherapy. two years after surgery, no signs of recurrence have been noted. The present findings can help clinicians make an accurate preoperative imaging diagnosis of gynandroblastoma with a juvenile granulosa cell component and plan an adequate treatment strategy for this rare, potentially malignant neoplasm

    Uterine torsion of 90 degrees: case report

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    Uterine torsion is defined as a rotation of uterus more than 45 degrees along its long axis. However, a pathologic rotation of the uterus beyond 45 degrees-torsion of the entire uterus-is rarely seen in obstetrical practice, authors report a case of torsion of the uterus by 90 degrees. The patient, a 30-year-old gravida 3 para 2 at 37 weeks’ gestation with a singleton pregnancy, her prior obstetrical history included two uncomplicated term vaginal deliveries, and the current pregnancy had been uncomplicated until the date of presentation was admitted to the obstetrical unit  with  labour at 37 weeks 5 days ,on obstetric examination the patient was in labour with transversal presentation of the fetus so an emergency caesarean section (CS) was carried out for. At the time of CS, the diagnosis of uterine torsion of 90 degrees was made. After the delivery of the baby, uterus returned to anatomical position and the torsion corrected spontaneously. The patient recovered and was discharged home with her baby on the third postoperative day. Uterine torsion is an infrequently reported and potentially dangerous complication of pregnancy that occurs mainly in the third trimester

    Evaluation of Some Biomarker and Genetic Marker in Myocardial Infraction Patients

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    Acute coronary syndrome (ACS) consists of unstable angina pectoris, non-ST segment elevation myocardial infarct ion and ST segment elevate ion myocardial infarction.  The aim of the study was to compare the vibration  some hormones levels in the Acute coronary syndrome patients and control groups and This study aimed to investigate the association between two single nucleotide polymorphisms (?1562C>T, of the MMP-9 gene in patients with ACS in the Iraq population. Subjects and methods: This study was conducted between / mrjan teaching hospital in Babylon Province between November 2012- Aprial 2013and it was carried out at the coronary care unit  / in Babylon province/Iraq .  This patient-control study was composed of 60 ACS patients with age 53.38 ± 9.51 and 30control withe age  51.43 ± 7.81subjects, The present study is divided into two main parts: physio-biochemical and molecular parts. The physiological part involved hormonal assay( troponin and endothelin-1) while molecular part included The genotypes of the  selected SNPs were determined by the method of polymerase chain reaction and restriction fragment length polymorphism (RFLP-PCR). The relationship between the polymorphism of the MMP-9 gene and the severity of Acute coronary syndrome with negative medical history. The result of this study showed that patients with Acute coronary syndrome both males and females had significantly troponin and elevated Endothelin -1 in patient than control<0.001**(**p value ? 0.01 was significant).Analysis of the SNPs showed that the frequency of CT and TT genotypes in patients with ACS was significantly higher than that in the control group (ACS vs. controls; CT+TT: (85%Vs 36%). Keywords:single nucleotide polymorphisms, troponin, endotheline, MMP-

    Effect of Uric Acid and Lipid Profile on Myocardial Infarction in Iraqi Population

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    Myocardial infarction is a common presentation of coronary artery disease. This study was aimed to evaluate the effect of uric acid and lipid profile on myocardial infarction in Iraqi population. The study was conducted on (30) patients acute myocardial infarction, and (30) apparently healthy subjects were taken as control group. The level of uric acid and lipid profile was determined using colorimetric method. Patient group had significantly higher level of uric acid (P < 0.01), total cholesterol (P < 0.01), triglyceride (P < 0.01), low density lipoprotein (P < 0.01), very low density lipoprotein (P < 0.01) and significantly lower level of high density lipoprotein (P < 0.01) than control group. The results of this study also showed a significant difference (P < 0.01) between males and females regarding uric acid, total cholesterol, triglyceride, low density lipoprotein, very low density lipoprotein and high density lipoprotein in both study groups. The body weight of the patients demonstrated as body mass index showed a significant association (P < 0.01) with the level of uric acid, total cholesterol, triglyceride, low density lipoprotein and high density lipoprotein in patient group. In conclusion, uric acid may have an effect on precipitating some risk factors of myocardial infarction. Key words: Uric acid, lipid profile, myocardial infarction
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