<Preliminary>Stereochemical Selectivity in Secoisolariciresinol Formation by Cell-free Extracts from Arctium lappa L. Ripening Seeds

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Paleomagnetic Studies on Miocene Sequences of Hokutan and Tottori Groups in Southwest Japan: Implications for Middle Miocene Rotational Movement of Southwest Japan Block Associated with the Japan Sea Opening

Miocene sequences composed of volcanic rocks and overlying marine sediments distributing at the Japan Sea side of Southwest Japan have been considered to form related to the rifting and subsequent spreading of the Japan Sea back-arc basin in Miocene time. We performed paleomagnetic investigations on the sequences in the eastern San’in district, the Hokutan and Tottori Groups. Paleomagnetic analyses on samples from 33 sites indicated that characteristic magnetic components from five sites of volcanic rocks in the Hokutan Group and from four sites of marine sediments in the Tottori Group were regarded as primary components. An obtained paleomagnetic direction of the volcanic rocks has an easterly deflected declination (D = 23.9° ± 20.2°), while that of the marine sediments shows no significant deflection in declination (D = 17.8° ± 19.1°). Through the comparison with paleomagnetic data from the Miocene sequences in Southwest Japan, it is suggested that magnetic polarities of the volcanic and sedimentary sequences are assigned to C5Cn and C5Br-C5Bn, respectively, and that the eastern San’in district suffered a clockwise rotation of 24° at around 16 Ma after the early Miocene volcanic activity and before the middle Miocene marine transgression in the whole clockwise rotation process of Southwest Japan related to the Japan Sea opening

Quantum state tomography for Kerr parametric oscillators

Kerr parametric oscillators (KPOs) implemented in the circuit QED architecture can operate as qubits. Their applications to quantum annealing and universal quantum computation have been studied intensely. For these applications, the readout of the state of KPOs is of practical importance. We develop a scheme of state tomography for KPOs with reflection measurement. Although it is known that the reflection coefficient depends on the state of the KPO, it is unclear whether tomography of a qubit encoded into a KPO can be performed in a practical way mitigating decoherence during the measurement, and how accurate it is. We show that the reflection coefficient has a one-to-one correspondence with a diagonal element of the density matrix of the qubit when a probe frequency is properly chosen and an additional single-photon-drive is introduced. Thus, our scheme offers a novel way to readout the qubit along an axis of the Bloch sphere, and therefore the reflection measurement and single-qubit gates can constitute state tomography

Cosmic Galaxy-IGM HI Relation at z∼2−3{\it{z}}\sim 2-3 Probed in the COSMOS/UltraVISTA 1.61.6 deg2^2 Field

We present spatial correlations of galaxies and IGM HI in the COSMOS/UltraVISTA 1.62 deg$^2$ field. Our data consist of 13,415 photo-$z$ galaxies at $z\sim2-3$ with $K_s<23.4$ and the Ly$\alpha$ forest absorptions in the background quasar spectra selected from SDSS data with no signature of damped Ly$\alpha$ system contamination. We estimate a galaxy overdensity $\delta_{gal}$ in an impact parameter of 2.5 pMpc, and calculate the Ly$\alpha$ forest fluctuations $\delta_{\langle F\rangle}$ whose negative values correspond to the strong Ly$\alpha$ forest absorptions. We identify weak evidence of an anti-correlation between $\delta_{gal}$ and $\delta_{\langle F\rangle}$ with a Spearman's rank correlation coefficient of $-0.39$ suggesting that the galaxy overdensities and the Ly$\alpha$ forest absorptions positively correlate in space at the $\sim90\%$ confidence level. This positive correlation indicates that high-$z$ galaxies exist around an excess of HI gas in the Ly$\alpha$ forest. We find four cosmic volumes, dubbed $A_{obs}$-$D_{obs}$, that have extremely large (small) values of $\delta_{gal} \simeq0.8$ ($-1$) and $\delta_{\langle F\rangle}$ $\simeq0.1$ ($-0.4$), three out of which, $B_{obs}$-$D_{obs}$, significantly depart from the correlation, and weaken the correlation signal. We perform cosmological hydrodynamical simulations, and compare with our observational results. Our simulations reproduce the correlation, agreeing with the observational results. Moreover, our simulations have model counterparts of $A_{obs}$-$D_{obs}$, and suggest that the observations pinpoint, by chance, a galaxy overdensity like a proto-cluster, gas filaments lying on the sightline, a large void, and orthogonal low-density filaments. Our simulations indicate that the significant departures of $B_{obs}$-$D_{obs}$ are produced by the filamentary large-scale structures and the observation sightline effects.Comment: 14 pages, 12 figures. Accepted for publication in Ap

Follow-up study of cartilaginous bone tumors.

A series of clinical and pathological studies were performed on 74 cartilaginous bone tumors including osteochondromas, multiple cartilaginous exostoses, chondromas, chondromatoses, benign chondroblastomas and chondrosarcomas. Resection was adequate for the osteochondromas, and no recurrence was observed. Out of 14 multiple cartilaginous exostoses, three, all in flat bones showed malignant change. The predominant sites of chondroma were the finger and toe bones, and curettage and bone graft was adequate treatment. Neither recurrence nor malignant change was observed. Two cases of chondromatosis, one of Ollier's disease and one of Maffucci's syndrome, were included in our series. Leg length discrepancy and pathologic fracture were common problems in chondromatosis. Moreover, malignant change was suspected in a hemangioma of the Maffucci's syndrome patient. Benign chondroblastoma was treated by curettage and bone graft, with no recurrence. In our series, 4 primary and 3 secondary chondrosarcomas were observed. Metastasis was seen in only one case. Because of the discrepancy between the biological behavior and histological findings of cartilaginous bone tumors, the malignancy of tumors should be evaluated by clinical signs and symptoms as well as by histological findings.</p

Validating Variational Bayes Linear Regression Method With Multi-Central Datasets.

PurposeTo validate the prediction accuracy of variational Bayes linear regression (VBLR) with two datasets external to the training dataset.MethodThe training dataset consisted of 7268 eyes of 4278 subjects from the University of Tokyo Hospital. The Japanese Archive of Multicentral Databases in Glaucoma (JAMDIG) dataset consisted of 271 eyes of 177 patients, and the Diagnostic Innovations in Glaucoma Study (DIGS) dataset includes 248 eyes of 173 patients, which were used for validation. Prediction accuracy was compared between the VBLR and ordinary least squared linear regression (OLSLR). First, OLSLR and VBLR were carried out using total deviation (TD) values at each of the 52 test points from the second to fourth visual fields (VFs) (VF2-4) to 2nd to 10th VF (VF2-10) of each patient in JAMDIG and DIGS datasets, and the TD values of the 11th VF test were predicted every time. The predictive accuracy of each method was compared through the root mean squared error (RMSE) statistic.ResultsOLSLR RMSEs with the JAMDIG and DIGS datasets were between 31 and 4.3 dB, and between 19.5 and 3.9 dB. On the other hand, VBLR RMSEs with JAMDIG and DIGS datasets were between 5.0 and 3.7, and between 4.6 and 3.6 dB. There was statistically significant difference between VBLR and OLSLR for both datasets at every series (VF2-4 to VF2-10) (P &lt; 0.01 for all tests). However, there was no statistically significant difference in VBLR RMSEs between JAMDIG and DIGS datasets at any series of VFs (VF2-2 to VF2-10) (P &gt; 0.05).ConclusionsVBLR outperformed OLSLR to predict future VF progression, and the VBLR has a potential to be a helpful tool at clinical settings

Effect of cysteine on the inactivation of cystathionine gamma-lyase by D,L-propargylglycine.

In vivo inactivation of cystathionine gamma-lyase by D,L-propargylglycine, a suicide inhibitor, was found to be less profound in rat kidney than in the liver. We investigated the cause of this difference using rat tissues. We fractionated kidney extract to characterize the substance which protected enzyme, and found that cysteine exhibits protecting action. Addition of 0.3 mM L-cysteine to the incubation mixture containing dialyzed kidney supernatant and 0.5 mM D,L-propargylglycine resulted in the protection of cystathionine gamma-lyase from the inactivation by the inhibitor. The content of cysteine in the kidney was six-fold higher than that in the liver. Thus, we have concluded that one of the reasons why the in vivo inactivation of cystathionine gamma-lyase in rat kidney was less than that in the liver is the presence of a higher concentration of cysteine in the kidney. S-Carboxymethylcysteine, a cysteine derivative, exhibited a similar, but weaker, protective effect.</p

Radioanatomical study of the bronchovascular anomalies of the middle and lower lobes of the right lung using multidetector computed tomography

石川県済生会金沢病院放射線部金沢大学医薬保健研究域保健学系Objective:: Preoperative evaluation of bronchovascular structures is useful for prevention of accidents in pulmonary lobectomy. The purpose of this study was to examine the frequency and multidetector computed tomographic (CT) appearances of bronchovascular anomalies between the right middle and lower lobes. Methods:: A total of 1116 consecutive chest CT examinations were analyzed in the present study. On display, the bronchovascular anomalies between the right middle and lower lobes were searched. When anomalous structures were observed, 3-dimensional images were reconstructed. Results:: Sixty-seven cases (6.0%) with anomalous findings were observed. In 20 cases (1.79%), the right middle lobe bronchus and artery supplied the lower lobe, whereas the lower lobe artery supplied the right middle lobe in 46 cases (4.12%). In 1 case (0.09%), the 2 patterns previously mentioned were observed concomitantly. Conclusions:: Anomalous bronchovascular structures between the right middle and lower lobes were identified by a multidetector CT with an incidence of 6.0%. Knowledge of the frequency and CT features is useful for preoperative CT evaluation. © 2009 Lippincott Williams & Wilkins