Risk of Malnutrition and Its Effects on the Quality of Life of Hospitalized Cancer Patients

Aim:Malnutrition is one of the most common clinical problems in cancer patients. Its frequency increases in hospitalized cancer patients. In this study, it was aimed to investigate the frequency of malnutrition and its effect on quality of life (QOL) in hospitalized cancer patients.Materials and Methods:In this cross-sectional study, Nutrition Risk Screening-2002 (NRS-2002) and European Organization for the Research and Treatment of Cancer (EORTC)-QLQ C30 scales were completed for patients with cancer diagnosed in the medical oncology service. The relationship between clinical and laboratory parameters, malnutrition risk and QOL was analyzed by statistical methods.Results:One-hundred thirteen patients were included in the study. According to the results of NRS-2002, 42.5% (n=48) patients were at risk of malnutrition. There was no difference between the groups in terms of gender and age. When the EORTC-QLQ C30 scale scores were compared, the risk of malnutrition had no effect on the overall health score (p=0.679). Physical function and role function scores were significantly lower in those at risk of malnutrition (worse QOL). There was no statistically significant difference between the groups in terms of other functional scales. When univariate logistic regression (LR) was applied to the factors affecting better general health score, only hemoglobin level was found to be a significant factor. Therefore, multivariate LR was not done.Conclusion:Malnutrition risk assessment should be performed routinely in every hospitalized cancer patient. Early nutritional support should be given to patients at risk. It was observed that patients with malnutrition risk had worse QOL compared to the EORTC-QLQ C30 scale

A bibliometric analysis of sarcopenia: top 100 articles

Key summary pointsAim The main aim of this bibliometric study is to investigate trends in the field of sarcopenia and guide to most cited articles for researchers. Findings The number of citations about sarcopenia has increased significantly year by year. The most investigated topics about sarcopenia are definition-diagnosis, prognosis, and treatment-recommendation of sarcopenia, respectively. Message This study demonstrates the important issues about sarcopenia in the past and present, and suggests possibilities for the future of this dynamic field

ASSOCIATION OF NEURODEGENERATIVE DISEASES WITH SARCOPENIA AND OTHER GERIATRIC SYNDROMES

Introduction: This study aimed to evaluate the association between two most common neurodegenerative diseases, Alzheimer's disease and Parkinson's disease, with sarcopenia and other common geriatric syndromes

A Fuzzy Dematel Method To Evaluate The Most Common Diseases In Internal Medicine

Most patients have more than one disease, and these diseases are able to affect one another. In modern medicine, the etiology and pathophysiology of diseases are well known in detail. However, inter-disease relationships are still mysterious. Physicians' knowledge and experience have great importance in such a multi-criteria case. Because medical doctors in internal medicine clinics deal with large numbers of patients with multiple diseases, they have quite a complex approach in treating illness. In this context, exposing the cause-and-effect relationships among diseases frequently seen in internal medicine will contribute to physicians' ability to blend profound theoretical knowledge with experiential results. Therefore, this study presents a fuzzy DEMATEL (Decision-Making Trial-and-Evaluation Laboratory) method to assess the most common diseases in internal medicine outpatient clinics. The DEMATEL method allows one to identify and analyze significant diseases in internal medicine by considering the cause-and-effect relationship diagram. Likewise, fuzzy sets in DEMATEL overcome the uncertainty in making decisions about disease relationships and internal medicine experts' judgments. When investigating the results, we have found dyspepsia, hyperlipidemia, and anemia to be crucial in terms of causes. When evaluating the effects, the most notable diseases are understood to be renal failure, malignancy, and hepatitis. The results indicate that in the presented study, we could successfully apply these methods to reveal the cause-effect of diseases. The results of this study will contribute to understanding the complex multi-criteria relationship among internal diseases using internists' opinions

Comparison of attention for malnutrition research on social media versus academia: Altmetric score analysis

Objectives: In this study, we aimed to provide bibliometric and Altmetric overviews and visualization and to evaluate the correlation between traditional bibliometric and Altmetric analyses in the field of malnutrition

Association of sarcopenia with geriatric syndromes and neutrophil / lymphocyte ratio

We aimed to search the relationship of sarcopenia with chronic diseases, geriatric syndromes and neutrophil/lymphocyte ratio (NLR). Our study included 258 patients who were admitted to Cerrahpaşa Medical Faculty geriatrics outpatient clinic for the first time between March 2018 and February 2019, and underwent comprehensive geriatric evaluation. Patients under 65 years of age, with active infection, terminal illness, diagnosis of malignancy, presence of trauma and infection in the last month were excluded from the study. Sarcopenia was present in 77 (30%) of the 258 participants involved in the study. Frequency of diabetes mellitus, dementia, delirium, polypharmacy and malnutrition was statistically significantly higher in patients with sarcopenia compared to patients without sarcopenia (p=0.020, p=0.024, p=0.016, p=0.018 and p [Med-Science 2022; 11(2.000): 645-50

Themes and trends for osteoporosis: the bibliometric and altmetric approach

Our aim is to evaluate and compare the most discussed articles on osteoporosis in academia and social media. The treatment of osteoporosis was the most popular topic in the top 100 citation (n = 31) and altmetric lists (n = 47). The general public, as well as academia, is curious about the treatment of osteoporosis. Purpose The main aim of this study is to investigate the trends in the field of osteoporosis and guide researchers by conducting bibliometric and altmetric analysis for osteoporosis with the most cited and discussed articles on social media. Methods The keyword "osteoporosis" was searched from the Web of Science All Databases and Altmetric.com website, and the top 100 (T100) citation and altmetric list was created, respectively. The T100 citation and altmetric list articles were analyzed and compared in terms of study type, topic of study, first author, publication year, citation number, journal quartile in category, impact factor, and Altmetric Attention Score (AAS). Results T100 cited articles: the median for citation number was 1117 (range: 717-3854) and the median for AAS was 9 (range: 0-371). T100 altmetric articles: the AAS median was 158 (range: 93-658) and citation number median was 31 (range: 0-2132). Only 6 articles were the same in both lists. The number of articles about treatment was 31 in the T100 citation list and 47 in the T100 altmetric list. The most ranked journals were "The New England Journal of Medicine" with 22 articles in the T100 citation list and "Osteoporosis International" with 16 articles in the T100 altmetric list. Conclusion Unlike the citation number, one of the greatest contributions of AAS to researchers may be developing appropriate policies in the field of osteoporosis according to the interests of the society

Sarcopenia assessment by new EWGSOP2 criteria for predicting chemotherapy dose-limiting toxicity in patients with gastrointestinal tract tumors

Introduction In 2019, The EWGSOP2 group made updates on the definition and diagnosis of sarcopenia. The aim of this study is to determine the possible risk factors for chemotherapy dose-limiting toxicity (DLT). Methods Newly diagnosed gastrointestinal (GI) cancer patients were included in this prospective observational study. Chemotherapy DLTs were recorded in patients receiving platinum-based therapy. The patients were divided into two groups according to the current sarcopenia criteria. Results 75 patients were included in the final analysis. Chemotherapy DLT occurred in 52% (n = 39) of all patients who received platinum-based chemotherapy. DLT rates were 78.9% and 42.9% in sarcopenic and non-sarcopenic patients, respectively (p = 0.007). According to the results of the multivariate analysis, the only sarcopenia was found as a statistically significant risk factor for DLT. Conclusion Assessment of sarcopenia evaluated with the current EWGSOP2 diagnostic criteria is useful in predicting chemotherapy DLT development in patients with a diagnosis of GI cancer. In the future, current EWGSOP2 recommendations should be considered while designing a study investigating the correlation between sarcopenia and chemotoxicity

Association between anticholinergic drug burden with sarcopenia, anthropometric measurements, and comprehensive geriatric assessment parameters in older adults

Background: Older patients use multiple drugs due to their comorbidities and most of these drugs have anticholinergic drug burden (ADB). We aimed to investigate the association between ADB and sarcopenia, anthropometric measurements, and comprehensive geriatric assessment (CGA) parameters in older adults

Association of FGF-19 and FGF-21 levels with primary sarcopenia

Aim Serum fibroblast growth factor (FGF)-19 and FGF-21 levels have been reported to be associated with muscle hemostasis. This study aims to explore the relationship between the levels of these markers and sarcopenia. Methods In our single-center, cross-sectional study, patients over 65 years old presenting to the geriatric outpatient clinic were included. Patients with secondary sarcopenia were excluded. The Strength-Assistance with walking-Rising from a chair-Climbing stairs and Falls (SARC-F) questionnaire was applied to all patients. Sarcopenia was determined by handgrip strength (HGS), bioelectrical impedance analysis and 6-m walk test. Serum samples were stored at -80 degrees C until measurement. The ELISA method was used to assess FGF-19 and FGF-21 levels. Results In total, 88 patients (54 women) were included. There were 43 patients in the sarcopenia group and 45 patients without sarcopenia in the control group. In those with sarcopenia, FGF-19 was lower (P = 0.04) and FGF-21 was higher (P = 0.021). There was a direct correlation between FGF-19 with SARC-F and HGS (P = 0.04, B = 0.178, P = 0.006, B = 0.447) while FGF-21 was inversely correlated with HGS and positively correlated with 6-m walking time (P = 0.016, B = -0.428, P = 0.004, B = 0.506). Conclusions Our results reveal that low FGF-19 and high FGF-21 may be associated with sarcopenia and this finding could be explained by the impacted muscle strength. Geriatr Gerontol Int center dot center dot; center dot center dot: center dot center dot-center dot center dot Geriatr Gerontol Int 2021; center dot center dot: center dot center dot-center dot center dot