Platelet-rich plasma versus corticosteroid injections in the management of patients with rotator cuff disease: A systematic review and meta-analysis.

Platelet-rich plasma (PRP) is an alternative to corticosteroid (CS) injections in managing rotator cuff disease. This meta-analysis investigated differences between PRP and CS for function and pain scores in significance and minimal clinical important difference (MCID). A literature search of Ovid Cochrane Library, Medline, Embase, Epub, and Scopus was conducted from inception to October 28, 2021. Eligible studies reported patients older than 18 years with a diagnosis of rotator cuff disease. This review was registered in PROSPERO (ID: CRD42021278740). Twelve studies met eligibility criteria (n = 639) of patients receiving either PRP or CS. At short-term follow-up, a difference favored CS compared to PRP in baseline change for disability of arm, shoulder, and hand (DASH) score (MD = -5.08, 95% CI: -8.00, -2.15; p = 0.0007; I2  = 0%) and simple shoulder test (SST) (MD = 1.25, 95% CI: 0.33, 2.18; p = 0.008; I2  = 0%). At intermediate follow-up, a difference favored PRP to CS baseline change of the DASH score (MD = 3.41, 95% CI: 0.67, 6.15; p = 0.01; I2  = 0%). At medium-term, a difference favored PRP to CS baseline change of the American Shoulder and Elbow Surgeons Shoulder (ASES) score (MD = -4.42, 95% CI: -8.16, -0.67; p = 0.02; I2  = 0%). Both treatments achieved individual MCID for each score. Despite favoring CS at short-term follow-up and PRP at intermediate- and medium-term follow-up, functional and pain scores did not demonstrate any clinical difference between the two treatment modalities in management of rotator cuff disease at all follow-up periods

Mycobacterium tuberculosis monoarthritis in a child

A child with isolated Mycobacterium tuberculosis monoarthritis, with features initially suggesting oligoarthritis subtype of juvenile idiopathic arthritis, is presented. This patient illustrates the need to consider the possibility of tuberculosis as the cause of oligoarthritis in high-risk pediatric populations even in the absence of a tuberculosis contact history and without evidence of overt pulmonary disease

Linear infinite cadmium chains in CaAu4Cd2 and other intermetallics with YbMo2Al4-type structure

International audienceNew YbMo2Al4-type cadmium compounds CaAu4Cd2, SrAu4Cd2, and EuAu4Cd2 were synthesized from the elements in sealed tantalum tubes. The structures of CaAu4Cd2 (I4/mmm, a = 710.7(1), c = 550.2(3) pm, wR2 = 0.026, 168 F 2 values, 10 variables) and EuAu4.80Cd1.20 (a = 716.6(1), c = 545.9(1) pm, wR2 = 0.024, 167 F 2 values, 11 variables) were refined from X-ray single-crystal diffractometry data. The gold and cadmium atoms show different substructures: Au4 squares (279 pm Au-Au in CaAu4Cd2) and cadmium chains (275 pm Cd-Cd in CaAu4Cd2). EuAu4Cd2 forms a solid solution EuAu4+x Cd2−x up to x ≈ 1, where almost every other cadmium atom within the chains is substituted by gold. Chemical bonding analyses on CaAu4Cd2 shows almost complete charge transfer from calcium to the [Au4Cd2] network. Bader charge analysis classifies CaAu4Cd2 as an auride. EuAu4Cd2 shows Curie-Weiss behavior above 25 K with an experimental magnetic moment of 7.86 μB/Eu atom, near to the free ion value of 7.94 μB for Eu2+ and orders ferromagnetically at T C = 16.3(5) K. 151Eu Mössbauer spectra show a single signal at an isomer shift of about −10 mm/s, compatible with divalent europium. At 5 K, and therefore clearly below T C, magnetic hyperfine splitting is observed