12,763 research outputs found
A simple deterministic self-organized critical system
We introduce a new continuous cellular automaton that presents self-organized
criticality. It is one-dimensional, totally deterministic, without any kind of
embedded randomness, not even in the initial conditions. This system is in the
same universality class as the Oslo rice pile system, boundary driven interface
depinning and the train model for earthquakes. Although the system is chaotic,
in the thermodynamic limit chaos occurs only in a microscopic level.Comment: System slightly modified. New results on Liapunov exponents.
Submitted for publication (8 pages
Chaos and Synchronized Chaos in an Earthquake Model
We show that chaos is present in the symmetric two-block Burridge-Knopoff
model for earthquakes. This is in contrast with previous numerical studies, but
in agreement with experimental results. In this system, we have found a rich
dynamical behavior with an unusual route to chaos. In the three-block system,
we see the appearance of synchronized chaos, showing that this concept can have
potential applications in the field of seismology.Comment: To appear in Physical Review Letters (13 pages, 6 figures
Iron overload and immunity
World J Gastroenterol. 2007 Sep 21;13(35):4707-15.
Iron overload and immunity.
Porto G, De Sousa M.
Institute of Molecular and Cellular Biology, Rua do Campo Alegre, Porto 8234150, Portugal. [email protected]
Abstract
Progress in the characterization of genes involved in the control of iron homeostasis in humans and in mice has improved the definition of iron overload and of the cells affected by it. The cell involved in iron overload with the greatest effect on immunity is the macrophage. Intriguing evidence has emerged, however, in the last 12 years indicating that parenchymal iron overload is linked to genes classically associated with the immune system. This review offers an update of the genes and proteins relevant to iron metabolism expressed in cells of the innate immune system, and addresses the question of how this system is affected in clinical situations of iron overload. The relationship between iron and the major cells of adaptive immunity, the T lymphocytes, will also be reviewed. Most studies addressing this last question in humans were performed in the clinical model of Hereditary Hemochromatosis. Data will also be reviewed demonstrating how the disruption of molecules essentially involved in adaptive immune responses result in the spontaneous development of iron overload and how they act as modifiers of iron overload.
PMID: 17729392 [PubMed - indexed for MEDLINE
Self-Similarity of Friction Laws
The change of the friction law from a mesoscopic level to a macroscopic level
is studied in the spring-block models introduced by Burridge-Knopoff. We find
that the Coulomb law is always scale invariant. Other proposed scaling laws are
only invariant under certain conditions.}Comment: Plain TEX. Figures not include
Exponential Distributions in a Mechanical Model for Earthquakes
We study statistical distributions in a mechanical model for an earthquake
fault introduced by Burridge and Knopoff [R. Burridge and L. Knopoff, {\sl
Bull. Seismol. Soc. Am.} {\bf 57}, 341 (1967)]. Our investigations on the size
(moment), time duration and number of blocks involved in an event show that
exponential distributions are found in a given range of the paramenter space.
This occurs when the two kinds of springs present in the model have the same,
or approximately the same, value for the elastic constants. Exponential
distributions have also been seen recently in an experimental system to model
earthquake-like dynamics [M. A. Rubio and J. Galeano, {\sl Phys. Rev. E} {\bf
50}, 1000 (1994)].Comment: 11 pages, uuencoded (submitted to Phys. Rev. E
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