ANALYTICAL METHODS FOR THE DETERMINATION OF AMINOGLYCOSIDES ANTIBIOTICS BY CHROMATROGRAPHIC TECHNIQUE

Aminoglycosides antibiotics are considered to be the antimicrobial agents used frequently in the treatment of human diseases caused by a bacterial infection. Most of the aminoglycosides antibiotics are highly polar in nature and they are lacking the UV absorbing chromophore in the molecules. The present articles accentuate the analytical method associated with the analysis of aminoglycosides molecules. Various chromatographic techniques like liquid chromatography, gas chromatography; mass spectrometry were used for the detection of aminoglycosides antibiotics. However, due to its limitation in the ultraviolet-visible spectrophotometry (UV/Vis) technique, different types of detection techniques like corona-charged aerosol detector (CAD), electrochemical detector (ECD) were used as a most powerful and versatile technique for the demonstration of these molecules in the analytical field. Analytical methods help to ensure the quality of the drug products. This review paper is devoted to providing an overview of the key performance technique used for the application and detection of these aminoglycosides molecules

A CNN Based Approach for Garments Texture Design Classification

Identifying garments texture design automatically for recommending the fashion trends is important nowadays because of the rapid growth of online shopping. By learning the properties of images efficiently, a machine can give better accuracy of classification. Several Hand-Engineered feature coding exists for identifying garments design classes. Recently, Deep Convolutional Neural Networks (CNNs) have shown better performances for different object recognition. Deep CNN uses multiple levels of representation and abstraction that helps a machine to understand the types of data more accurately. In this paper, a CNN model for identifying garments design classes has been proposed. Experimental results on two different datasets show better results than existing two well-known CNN models (AlexNet and VGGNet) and some state-of-the-art Hand-Engineered feature extraction methods

Erosive Potential of Various Beverages in the United Arab Emirates: pH Assessment

Objectives: The United Arab Emirates (UAE) is one of the top 5 countries in the world in terms of juice consumption per capita. The rising consumption of beverages is a major contributor to a plethora of diseases, including heightened risks of developing obesity, diabetes, and osteoporosis. Beverages with low pH also tend to magnify the risk of long-term dental erosion. This paper evaluated the pH of various beverages in the UAE to help determine their erosive potential. Materials and Methods: 306 beverages were collected from different stores in the UAE. Drinks were categorized into 8 categories: carbonated drinks, energy drinks, sparkling water, iced teas, juices, malt beverages, coconut water, and sports drinks. Three readings were taken for each drink using a pH meter at room temperature. Results: 88% of all beverages had a pH of less than 4.0, and the remaining 12% had a pH of 4.0 or more. 37% of the beverages tested were extremely erosive (pH < 3.0), 51% were erosive (pH 3.0–3.99), and 12% were mildly erosive (pH ≥ 4.0). Bickford’s Classic Cola and Tesco Lemon Juice were the most acidic beverages (pH < 2.4). The most identified acids in the tested beverages were citric, phosphoric, ascorbic, and malic acids. Conclusions: The majority of beverages in the UAE are erosive to dentition as the pH is below 4. Future studies to raise public awareness on the effect of acidic drinks on tooth structure are needed

Resin-Based Cement Applied to Enamel and Dentin Pre-Treated with Phytic Acid: An In Vitro Study

Phytic acid (IP6) has the ability to etch tooth structure due to its acidity and chelating properties. This study aimed to evaluate the micro-tensile bond strength (μTBS) of resin-based cement to enamel and dentin using manufacturer-provided etchants, phosphoric acid (PA) for enamel and a mixture of 10% citric acid and 3% ferric chloride (CAF) for dentin and compare them to IP6. Enamel surfaces were etched for 30 s with either PA or IP6 (1%, 5% or 10%). Dentin surfaces were etched for 15 s with either CAF or 1% IP6. Pre-polymerized composite blocks were bonded to enamel and dentin surfaces. After 24 h, the specimens were sectioned into beams and subjected to μTBS testing. De-bonded specimens and smear layer removal were analyzed with a scanning electron microscope. Etching enamel with 1% and 5% IP6 resulted in μTBS values that are comparable to the control (PA) (p > 0.05), while 10% IP6 negatively affected the μTBS (p p = 0.001). IP6 effectively removed enamel and dentin smear layer, and at specific concentrations, it may be a suitable alternative conditioner agent for bonding resin-based cement to enamel and dentin

In Vitro Optical and Physical Stability of Resin Composite Materials with Different Filler Characteristics

The objective of this study was to compare the physical and optical stability of resin composite materials with different filler characteristics. Ninety-six resin composite blocks (6 mm × 6 mm × 2 mm) were prepared using four different types of resin composite, divided into four groups. Specimens from the same material were randomly divided into four groups (n = 6) and allocated for Vickers hardness (VH), water sorption, solubility (WS/SL), and staining and aging challenges tests. One-way ANOVA showed significant differences in microhardness (p = 0.0001), WS (p = 0.0001), and SL (p = 0.003) among the tested groups. Beautifil II LS recorded the highest hardness, and CharmFil®Flow had the lowest value. Beautifil Injectable X and II LS showed negative WS, whereas the other groups had positive values. All groups showed positive SL. Repeated measures ANOVA showed significant color parameter alteration in the tested groups (p = 0.0001). All groups showed significant color shifting after one week of the staining challenge. Repeated measures ANOVA showed a significant color parameter (p = 0.0001) and weight (p = 0.001) alteration after the aging challenge. The optical and physical stability of resin composites may vary according to filler characteristics. Clinicians should choose the composite as per the desired outcome

Tinnitus Prevalence and Associated Factors among Dental Clinicians in the United Arab Emirates

Dental clinicians are at increased risk for developing tinnitus due to exposure to high levels of occupational noise. This study aimed to determine tinnitus prevalence and associated factors among dental clinicians. Interviews were conducted with 150 randomly selected dental clinicians using a questionnaire. Noise levels were measured at three points of time at the operating area. Tinnitus was reported in 19.33% of the participants. The average noise level was significantly higher among participants with tinnitus compared to those without the condition. More participants complained of intermittent tinnitus and the rest had the constant type, with the latter being significantly more bothersome. The weekly average time of using high-speed handpieces, suction and electric handpieces, age and experience had a significant effect on the presence of tinnitus. Only 2.7% of the participants reported the use of a hearing protection device. Tinnitus is a common finding among dental clinicians especially those with higher levels of occupational noise and more frequent use of noise-generating equipment. Knowledge of tinnitus prevalence aids in realizing the extent of its impact and making informed decisions. These results call for improved awareness of the negative impact of clinically-generated noise and emphasize the importance of preventive measures and periodic audiometry exams

Association between Salivary Cortisol Levels, Dental Anxiety, and Dental Caries in Children: A Cross-Sectional Study

Aim: This study aimed to investigate the relationship between dental caries, dental anxiety, and salivary cortisol levels in children visiting pediatric dental clinics and their implications on pediatric oral health. Materials and Methods: A cross-sectional study was conducted at a dental university in the UAE. A total of 60 children, aged 4–12 years, were included. Salivary cortisol levels were measured using an Enzyme-Linked Immunosorbent Assay (ELISA) kit. Dental caries status was evaluated, and dental anxiety levels were assessed using the Modified Dental Anxiety Scale (MDAS). Statistical analyses, including Mann-Whitney U test and Pearson’s correlation coefficient, were performed to determine significant differences and associations. Results: The study group showed significantly higher salivary cortisol levels compared to the control group (p p p = 0.85). A strong positive correlation was found between dental anxiety levels and dental caries status (p < 0.001). Conclusion: The findings indicate a significant association between salivary cortisol levels and dental caries, suggesting that higher cortisol levels are associated with active caries. Dental anxiety levels were positively correlated with dental caries. Understanding the relationship between these variables can contribute to better oral health strategies and interventions for children, emphasizing the importance of managing dental anxiety and stress in pediatric dental care. Clinical Significance: This study highlights the potential of salivary cortisol as a biomarker for assessing stress and its impact on oral health in children. By addressing dental anxiety and stress, dental professionals can provide child-friendly dental care, enhance preventive measures, and improve oral health outcomes in pediatric patients