2,326 research outputs found
My Voice Is Tired: The Reclamation of Voice Through the Expressive Arts to Aid in Self-Care and Processing for BIPOC Interns and Therapists Amidst Microaggression Experiences: A Literature Review and Autoethnography
This thesis centers the experiences of Black Indigenous People of Color (BIPOC) interns and therapists’ with microaggression and racism within their various environments. The impact and consequences of these experiences are discussed. An assortment of self-care and coping strategies for the experience of racism is examined, including the use of the expressive arts for self-care, reclamation of voice and processing. The El Duende One Canvas Process Painting technique was selected as the expressive arts tool for BIPOC interns and therapists to engage in to reclaim their voice. This author conducted an autoethnographic inquiry using the El Duende One Canvas Process Painting to process their own experiences of micro-aggression and self-care. The author’s artwork is integrated within the thesis for readers to gift levity and respite from witnessing
Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis
As a continuation of our previous work that turned toward the identification of antimycobacterial compounds with innovative structures, two series of pyrazole derivatives were synthesized by parallel solution-phase synthesis and were assayed as inhibitors of Mycobacterium tuberculosis (MTB), which is the causative agent of tuberculosis. One of these compounds showed high activity against MTB (MIC = 4 μg/mL). The newly synthesized pyrazoles were also computationally investigated to analyze their fit properties to the pharmacophoric model for antitubercular compounds previously built by us and to refine structure–activity relationship analysis
Ribonucleic Acid: Studies on Ribonucleic Acid in Relation to Cell Structure
1. A method for the separation of ribonucleotides by ionophoresis on filter paper is described. 2. A procedure for the partial isolation of RNA from animal tissues is described. 3. The technique of ionophoresis has been applied to the analysis of samples of isolated and partially isolated ribonucleic acid from various sources. 4. It has also been applied to the analysis of the ribonucleotide fraction obtained from animal tissues by a modification of the Schmidt and Thannhauser separation procedure. 5. The technique of ionophoresis together with that of partial isolation of the RNA is particularly useful in experiments with radioactive phosphorus, since it enables the ribonucleotides to be isolated free from contamination by non-nucleotide radioactive substances. 6. By a combination of ionophoresis and autoradiography, it has been demonstrated that the ribonucleotide fraction obtained by the Schmidt and Thannhauser procedure contains, in addition to the ribonucleotides, small amounts of inorganic phosphate of high specific activity probably derived from phosphoprotein, and at least 5 other protein bound phosphorus containing substances. 7. The presence of these additional components which amount to about 25% of the ribonucleotide fraction, renders estimates of the RNA content of animal tissues by the Schmidt and Thannhauser procedure high by about 30%. 8. In the cases of animals which have received 2 hr. before killing, the presence of these additional components which have high specific activities makes it impossible to obtain any estimate of the specific activity of the RNA by measurements on the ribonucleotide fraction itself. 9. Specific activity determinations on the nucleotides separated by ionophoresis from the partially isolated RNA and from isolated RNA Indicate that adenylic acid exhibits the highest value, while guanylic acid exhibits the lowest. 10. The technique of ionophoresis has been applied to the analysis of the ribonucleic acids from the cytoplasmic fractions. It was found that the composition of each was similar. 11. Ionophoresis of the ribonucleotides from the three cytoplasmic fractions 2 hr. after injection of 32P showed that adenylic acid in each case bad the highest specific activity and guanylic acid the lowest. 12. Of the three fractions, the microsome fraction invariably showed the lowest uptake of 32P into the ribonucleotides 2 hr. after injection. 13. It was found that the uptake of radioactive phosphate into each of the ribonucleotides of any of the fractions varied with time in the same fashion. 14. Using cytidylic acid as representative, it was found that the variation with time of the specific activities of the nucleotides from each of the fractions was the same
Do volcanoes trigger climate change?
This is the final version of the article. Available from NERC via the URL in this record.Huge volcanic eruptions may have pushed the climate from global warming to global cooling 16 million years ago. The theory could have big implications for efforts to slow climate change by fertilising plankton in the ocean. Sev Kender, Victoria Peck and John Smellie explain
Air Force Ni-H2 cell test program: State of Charge test
Nickel-Hydrogen cells are being cycled under a LEO (low earth orbit) test regime to examine the benefits of operating the cells at lower States of Charge (SOC) than typically used. A group of four cells are cycled using a voltage limiting charge regime that limits the State of Charge that the cells are allowed to reach. The test cells are then compared to identical cells being cycled at or near 100% State of Charge using a constant current charge regime
Antarctic Peninsula I : Volcanology
The fieldwork on which this chapter is based was undertaken by MJH in 1985-1988. The authors thank the British Antarctic Survey for originally supporting our project. Andy Saunders is also thanked for additional information on the Argo Point outcrop, and we are grateful to Janet Thomson for permission to publish her photograph of Mt Benkert.Peer reviewedPostprin
(E)-1-(2,5-Dimethylphenyl)-3-phenylprop-2-en-1-one
X-ray crystallography has been used to characterise the title compound for the first time, 1H NMR, 13C NMR and IR spectroscopic data has also been updated from earlier reports. We also report the melting point of the title compound.Peer reviewe
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