Photoclinic

Case presentation: A 20 month-old hypotonic boy with a history of preterm labor at 32 weeks of gestational age, secondary generalized seizures in infancy, hypothyroidism (T4: 2, TSH: 14); motor and speech developmental delay, mild  ataxia and renal failure (chronic kidney disease: CKD) was presented to the clinic of Taleghani pediatric hospital in Gorgan, Northern Iran during 2015. In further evaluation, the patient did not have fix and follow occularly and the head of the left optic nerve was atrophic and congenitally malformed although it seemed the visual prognosis for the right eye was even good with just a slightly pale nerve. The renal ultrasonography showed an increase of general echo which was suggestive for congenital or parenchymal abnormalities. Dialysis was ordered but the patient's family declined. The Image of the infant brain in axial cut using MRI 1.5 Tesla marked molar tooth sign (MTS). The schematic view is also given. Conservative treatment including Scholl, anti-convulsant solution, (30 cc daily), ferrous sulfate (20 drops), calcium tablets carbonate (2 per day) and phenobarbital (5 mg/kg/bw divided in two parts) was administered for the patient. Diagnosis: Classic Joubert syndrome subtype: CORS (11q12.2 TMEM216) Joubert syndrome is a rare autosomal recessive disorder affecting the cerebellum and characterized by abnormal respiratory pattern and eye movements, hypotonia, ataxia, developmental retardation with neuropathological defects of cerebellum and brainstem comprising inherited hypoplasia or aplasia of vermis. This clinical entity is possibly under-reported with a prevalence of less than 1 per 100,000. This syndrome is prototype of congenital vermian hypoplasia. Treatment for Joubert syndrome is symptomatic and supportive. Infant stimulation and physical, occupational, speech and hearing therapy may benefit some patients. Infants with abnormal breathing patterns must be monitored

Evaluation of Clinical Characteristics of Patients with Non-Traumatic Subarachnoid Hemorrhage

BACKGROUND AND OBJECTIVE: Subarachnoid hemorrhage (SAH) is a common and horrible disease and high rate of neurological complications. Misdiagnosis leads to increased mortality and delayed onset of treatment. This aim of study was to investigate the clinical characteristics of patients with SAH in Mazandaran. METHODS: This research is descriptive and retrospective study on 110 non-traumatic SAH. Variables include age, sex, headache, swallowing disorder, speech impairment, syncope, hemiplegia, seizure, nausea and vomiting, as well as risk factors such as hypertension(HTN), diabetes(DM), hyperlipidemia(HLP), alcohol consumption, smoking, Ischemic heart disease(IHD) was extracted from the patients file. FINDINGS: The mean age of patients was 53±16.92 years. The most common non-traumatic SAH in the age group over 40, especially 40 to 60 years. The average hospital length of stay was 14.7±4.77 days. Hypertension (47.3%) is highest prevalence in the study population compared with other risk factors include DM,HLP,IHD,smoking,alcohol consumption and the headache was 80% and hemiplegia was 11.8%. CONCLUSION: All patients with sudden headaches, especially headaches that have a history of hypertension must be accurate and complete evaluation for SAH