11,222 research outputs found
An investigation into Calvinās use of Augustine
This article briefly investigates the use of Augustine as an authority from the early church in John Calvinās writings. Calvin frequently referred to and quoted Augustine in his writings. Augustine undoubtedly exerted an influence on Calvinās views and arguments. This article traces Calvinās use of Augustine in his writings chronologically as they were published since 1532. In addition, a data analysis provides relevant information in order to argue a scrutinised exposition of Augustineās influence on Calvinās thinking. The article does not try to compare the theologies of Augustine and Calvin, nor to establish a theory that would reveal Augustineās influence on Calvinās theology. This investigation suggests methodological help for further research in this regard
Collagen scaffold remodeling by human mesenchymal stem cells
DMM 2011 entitled: Re-engineering Regenerative MedicinePoster Session - Tissue Engineering: no. 82Type I collagen has been widely used as scaffold for tissue engineering because of its excellent biocompatibility and negligible immunogenicity. We previously have developed a collagen microencapsulation technology entrapping many cells including human mesenchymal stem cells (hMSCs) in microspheres made of nanofibrous collagen meshwork. Nevertheless, little is understood about how stem cells interact with and remodel the collagen meshwork. This study aims to investigate collagen remodeling by human mesenchymal stem cells (hMSCs) in terms of degradation, new matrix synthesis, and reāorganization. We ā¦postprin
Environmental impact of combined ITS traffic management strategies
Transport was responsible for 20% of the total greenhouse gas emissions in Europe during 2011 (European Environmental Agency 2013) with road transport being the key contributor. To tackle this, targets have been established in Europe and worldwide to curb transport emissions. This poses a significant challenge on Local Government and transport operators who need to identify a set of effective measures to reduce the environmental impact of road transport and at the same time keep the traffic smooth. Of the road transport pollutants, this paper considers NOx, CO2 and black carbon (BC). A particular focus is put on black carbon, which is formed through incomplete combustion of carboneous materials, as it has a significant impact on the Earthās climate system. It absorbs solar radiation, influences cloud processes, and alters the melting of snow and ice cover (Bond et al. 2013). BC also causes serious health concerns: black carbon is associated with asthma and other respiratory problems, heart attacks and lung cancer (Sharma 2010; United States Environmental Protection Agency 2012). Since BC emissions are mainly produced during the decelerating and accelerating phases (Zhang et al. 2009), ITS actions able to reduce stop&go phases have the potential to reduce BC emissions. This paper investigates the effectiveness of combined ITS actions in urban context in reducing CO2 and BC emissions and improving traffic conditions
Homological methods in feature extraction of multidimensional images
We show that the newly developed homology algorithms are helpful in imaging problems on the example of an algorithm extracting one dimensional features from a noisy image. We indicate that in some situations the global nature of this algorithm may become advantageous when compared with the standard algorithms based on skeletonization and pruning. The algorithm works in every dimension. Ā©2009 IEEE.published_or_final_versionThe 2nd International Congress on Image and Signal Processing (CISP'09), Tianjin, China, 17-19 October 2009. In Proceedings of 2nd CISP, 2009, p. 1-
Day-to-day dynamic traffic assignment model with variable message signs and endogenous user compliance
This paper proposes a dual-time-scale, day-to-day dynamic traffic assignment model that takes into account variable message signs (VMS) and its interactions with driversā travel choices and adaptive learning processes. The within-day dynamic is captured by a dynamic network loading problem with en route update of path choices influenced by the VMS; the day-to-day dynamic is captured by a simultaneous route-and-departure-time adjustment process that employs bounded user rationality. Moreover, we describe the evolution of the VMS compliance rate by modeling driversā learning processes. We endogenize traffic dynamics, route and departure time choices, travel delays, and VMS compliance, and thereby captur their interactions and interdependencies in a holistic manner. A case study in the west end of Glasgow is carried out to understand the impact of VMS has on road congestion and route choices in both the short and long run. Our main find- ings include an adverse effect of the VMS on the network performance in the long run (the āreboundā effect), and existence of an equilibrium state where both traffic and VMS compliance are stabilized
Local structure around Ga in ultrafine GaN/ZnO coaxial nanorod heterostructures
The structure of tubular GaN coaxially grown on ZnO nanorods with thickness of 6-12 nm was investigated using x-ray absorption fine structure (XAFS) at the Ga K edge. The XAFS measurements revealed that the GaN had a distorted-wurtzite structure, and that there were more distortions in the bond length of Ga-Ga pairs than in Ga-N pairs. However, no extra disorders were observed in any of the pairs. These results strongly suggest that Ga atoms first bonded to the ZnO template. Unlike other techniques, the XAFS determines structure around a selected species atom in nano-heterostructures. (c) 2006 American Institute of Physics.open1188sciescopu
Orientation-dependent x-ray absorption fine structure of ZnO nanorods
The local structure of two samples of vertically well-aligned ZnO nanorods with average diameters of 13 and 37 nm were studied using orientation-dependent x-ray absorption fine structure (XAFS) at the Zn K edge. The aligned ZnO nanorod samples were fabricated on sapphire (0001) substrates with a catalyst-free metalorganic vapor-phase epitaxy method. The XAFS measurements showed that both nanorod samples have a well-ordered wurtzite structure and that no vacancy was observed at either site of zinc or oxygen atoms. However, we found that in both samples the lattice constants of a and b were shrunken by similar to0.04 Angstrom while c was elongated by similar to0.1 Angstrom, compared with those of their bulk counterparts. Furthermore, there was a substantial amount of disorder in the bond length of the only Zn-O pairs located near the ab plane. This may suggest that the terminating atoms at the boundaries of the nanorods are oxygen atoms. (C) 2005 American Institute of Physics.open114545sciescopu
Adaptive Functional Diversification of Lysozyme in Insectivorous Bats
This work was supported by the National Natural Science Foundation of China (31172077 to S.Z.), an East China Normal University Fostering Project for National Top Hundred Doctoral Dissertations (PY2011012 to Y.L.), an Innovation Fund of East China Normal University (78210200 to G.H.), and a Biotechnology and Biological Sciences Research Council China Partnering Award (BB/G530392/1 to G.J., S.J.R., and S.Z.)
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Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production.
We investigated the role of Bruton's tyrosine kinase (Btk) in FcepsilonRI-dependent activation of mouse mast cells, using xid and btk null mutant mice. Unlike B cell development, mast cell development is apparently normal in these btk mutant mice. However, mast cells derived from these mice exhibited significant abnormalities in FcepsilonRI-dependent function. xid mice primed with anti-dinitrophenyl monoclonal IgE antibody exhibited mildly diminished early-phase and severely blunted late-phase anaphylactic reactions in response to antigen challenge in vivo. Consistent with this finding, cultured mast cells derived from the bone marrow cells of xid or btk null mice exhibited mild impairments in degranulation, and more profound defects in the production of several cytokines, upon FcepsilonRI cross-linking. Moreover, the transcriptional activities of these cytokine genes were severely reduced in FcepsilonRI-stimulated btk mutant mast cells. The specificity of these effects of btk mutations was confirmed by the improvement in the ability of btk mutant mast cells to degranulate and to secrete cytokines after the retroviral transfer of wild-type btk cDNA, but not of vector or kinase-dead btk cDNA. Retroviral transfer of Emt (= Itk/Tsk), Btk's closest relative, also partially improved the ability of btk mutant mast cells to secrete mediators. Taken together, these results demonstrate an important role for Btk in the full expression of FcepsilonRI signal transduction in mast cells
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