Orange Dogs and Memory Responses: Creativity in Spectating and Remembering

It looks cold, metallic, dangerous, but it is mesmerising. I am drawn to the floor, knowing it is made of glass, wanting to test it, try it out, measure its keep. I step onto the floor and feel the cracking underfoot. It gives way, a gentle bounce underneath whilst it creaks and splinters. I am exhilarated, and I anticipate with trepidation, that the glass will break. I hear other steps around me breaking the glass floor slowly but inexorably and here, underneath my shoe, more glass breaks. But the softness surprises me-the layers of glass cushion the step and give it that bounce. It feels alive. It is matter stretched to its limit as its molecules hold onto each other under the pressure, under the duress. It finds its strength in the mass, each sheet of glass resting on another, resisting the weight that forces it, inevitably, to break. But still, shattered, crushed, it holds its shape and the weight of my feet. It is defiant, laughing at my feeble weight, ridiculing my initial fright

SARS-CoV-2 Infections in Vaccinated and Unvaccinated Populations in Camp Lemonnier, Djibouti, from April 2020 to January 2022

The global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the disparity between developed and developing countries for infectious disease surveillance and the sequencing of pathogen genomes. The majority of SARS-CoV-2 sequences published are from Europe, North America, and Asia. Between April 2020 and January 2022, 795 SARS-CoV-2-positive nares swabs from individuals in the U.S. Navy installation Camp Lemonnier, Djibouti, were collected, sequenced, and analyzed. In this study, we described the results of genomic sequencing and analysis for 589 samples, the first published viral sequences for Djibouti, including 196 cases of vaccine breakthrough infections. This study contributes to the knowledge base of circulating SARS-CoV-2 lineages in the under-sampled country of Djibouti, where only 716 total genome sequences are available at time of publication. Our analysis resulted in the detection of circulating variants of concern, mutations of interest in lineages in which those mutations are not common, and emerging spike mutations

A Requirement for DNA Synthesis during Auxin Induction of Cell Enlargement in Tobacco Pith Tissue

IAA (indoleacetic acid) is known to induce cell enlargement without cell division in tobacco pith explants grown on an agar medium without added cytokinin. The very long lag period before IAA (2 × 10 −5 M ) stimulates growth, about 3 days, can be useful to study the metabolic changes which lead to the promotion of growth. When the disks are transferred to a medium without IAA after 2 days or less of treatment with IAA, the IAA does not stimulate growth. Disks transferred after 3 days, subsequently show an auxin response, almost as great as those given IAA continuously. At 5 × 10 −4 M , 5-fluorodeoxyuridine (FUDR), which inhibits DNA synthesis by blocking formation of thymidylate, completely suppresses the lAA-induced growth if it is added together with the IAA or 1 day later. When the FUDR is given 2 days after the IAA, there is a small increment of auxin-induced growth, and an even greater amount if added after 3 days. The period when exogenous auxin must be present to stimulate growth corresponds to the period of FUDR sensitivity. The FUDR inhibition is prevented by thymidine but not by uridine. Other inhibitors of DNA synthesis, hydroxyurea and fluorouracil, also inhibit auxin-induced growth. Thus DNA synthesis seems to be required for auxin induction of cell enlargement in tobacco pith explants. In contrast, FUDR does not inhibit auxin-induced growth in corn coleoptile and artichoke tuber sections.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74425/1/j.1399-3054.1971.tb03492.x.pd