On Fixed Point theorems in Fuzzy Metric Spaces in Integral Type

Abstract: This paper presents some common fixed point theorems for occasionally weakly compatible mappings in fuzzy metric spaces. Keywords: Occasionally weakly compatible mappings,fuzzy metric space

Hawking Fluxes, Back reaction and Covariant Anomalies

Starting from the chiral covariant effective action approach of Banerjee and Kulkarni [Phys. Lett. B 659, 827(2008)], we provide a derivation of the Hawking radiation from a charged black hole in the presence of gravitational back reaction. The modified expressions for charge and energy flux, due to effect of one loop back reaction are obtained.Comment: 6 pages, no figures, minor changes and references added, to appear in Classical and Quantum Gravit

Poster 90 Effect of Exercise on a Novel Clinical Test for Reaction Time

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146913/1/pmr2s171a.pd

Near real-time determination of earthquake source parameters for tsunami early warning from geodetic observations

Exemplifying the tsunami source immediately after an earthquake is the most critical component of tsunami early warning, as not every earthquake generates a tsunami. After a major under sea earthquake, it is very important to determine whether or not it has actually triggered the deadly wave. The near real-time observations from near field networks such as strong motion and Global Positioning System (GPS) allows rapid determination of fault geometry. Here we present a complete processing chain of Indian Tsunami Early Warning System (ITEWS), starting from acquisition of geodetic raw data, processing, inversion and simulating the situation as it would be at warning center during any major earthquake. We determine the earthquake moment magnitude and generate the centroid moment tensor solution using a novel approach which are the key elements for tsunami early warning. Though the well established seismic monitoring network, numerical modeling and dissemination system are currently capable to provide tsunami warnings to most of the countries in and around the Indian Ocean, the study highlights the critical role of geodetic observations in determination of tsunami source for high-quality forecasting

On Fixed Point theorems in Fuzzy 2-Metric Spaces and Fuzzy 3-Metric Spaces

In this paper, we give some new definitions of compatible mappings of types (I) and  (II) in fuzzy-2 metric space and fuzzy-3 metric space prove some common  fixed point theorems  for mappings under the condition of compatible mappings of types (I) and (II) in complete fuzzy-2 metric space and fuzzy-3 metric space. Our results extend, generalize and improve the corresponding results given by many authors. Keywords: Fuzzy metric space, Fuzzy 2-metric space, fuzzy-3 metric space ,Compatible mappings, Common fixed point

Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique

The present investigation describes the influence of the concentration of PEG 6000 as a melt binder and ratio of HPMC K4M : PVP on Zolpidem tartrate controlled-release tablet formulations using 32 full factorial design. The ratio of HPMC K4M and PVP K30 (X1) and the concentration of melt binder (X2) were selected as independent variables, and drug release at 1 hr (Q1), 4 hr (Q4), 8 hr (Q8), diffusion coefficient (n), and release rate constant (K) were selected as a dependent variable. Tablets were prepared by melt granulation technique and evaluated for various evaluation parameters. It was observed that concentration of melt binder had significant effect on Q1, Q4, n, and K Binder concentration 25% w/w was found optimum. Optimized formulation (F7) showed good similarity with theoretical profile of drug. The X2 variable had a significant effect on dependent variables, and the X1 variable had no significant effect on dependent variables

Formulation and Evaluation of Transdermal Patch of Repaglinide

Repaglinide has the half life of 1 hour, and bioavailability in the body is 56% due to first-pass metabolism. The total daily dose of Repaglinide is 16 mg (e.g., 4 mg four times daily depending on meal patterns); hence, it required frequent dosing. Transdermal patch of Repaglinide was prepared to sustain the release and improve bioavailability of drug and patient compliance. Different formulations were prepared by varying the grades of HPMC and concentration of PVP K30 by solvent casting method. The prepared formulations were evaluated for various parameters like thickness, tensile strength, folding endurance, % elongation, % moisture content, % moisture uptake, % drug content, in vitro drug release, in vitro permeation, and drug excipient compatibility. A 32 full factorial design was applied to check the effect of varying the grades of HPMC (X1) and PVP concentration (X2) on the responses, that is, tensile strength, percentage drug released in 1 hr (Q1), 9 hr (Q9), and diffusion coefficient as a dependent variables. In vitro release data were fitted to various models to ascertain kinetic of drug release. Regression analysis and analysis of variance were performed for dependent variables. The results of the F2 statistics between factorial design batches and theoretical profile were used to select optimized batch. Batch F6 was considered optimum batch which contained HPMC K100 and PVP (1.5%), showed release 92.343% up to 12 hr, and was more similar to the theoretical predicted dissolution profile (f2 = 69.187)