4 research outputs found

    Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

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    Cx43 in osteogenic cells controls both arms of the bone-remodeling cycle via direct actions on osteoblast differentiation and function and indirect modulation of osteoclastogenesis. These result in changes remindful of those that occur in skeletal disuse or aging and disclose a far broader function of Cx43 in skeletal biology

    Gap Junctions and Biophysical Regulation of Bone Cells

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