O problema do ethos da escrita de si em Montaigne e em Petrarca: do ensaio à epístola

Montaigne insists throughout the course of the Essays on his disdain for rhetoric. But as we try to expose here, his natural form includes itself to a large extent in the terms of rhetoric itself, under a particular usage of the precepts and conventions traditionally appropriate to the discourse in first person, especially those which regulated the sermo familiaris, genre recuperated for the first time in the Renaissance by Petrarch. We retake, in order to develop it, the fruitful intuition of Hugo Friedrich in his classical work about Montaigne's Essays, indicating its kinship with Petrarch's epistolary form, without, however, following him when he moves the essay away from the familiar epistle by interpreting the essay as a rupture with the rhetorical procedures and therefore with all the artistically worked prose of humanism.Montaigne insiste ao longo dos Ensaios em seu desprezo pela retórica. Mas como procuraremos mostrar aqui, sua forma natural inscreve-se em grande medida dentro dos termos da própria retórica, sob uma mobilização particular dos preceitos e convenções tradicionalmente apropriados à escrita em primeira pessoa, especialmente aqueles que regulavam o sermo familiaris, gênero recuperado pela primeira vez na Renascença por Petrarca. Retomamos assim, para desenvolvê-la, a fecunda intuição de Hugo Friedrich que, em sua clássica obra sobre os Ensaios de Montaigne, aponta o seu parentesco com a forma epistolar de Petrarca, sem, porém, acompanhá-lo quando distancia o ensaio da epístola familiar, por entendê-lo como marco de ruptura com os procedimentos da retórica e, assim, com toda a prosa artisticamente trabalhada do humanismo.Universidade Federal de São Paulo (UNIFESP) Departamento de FilosofiaUNIFESP, Depto. de FilosofiaSciEL

A "sagesse" de Montaigne de duas perspectivas: do "otium" ao "negotium"

 The article examines the particular manner in which Montaigne positions itself in the defense of Otium in the context of the classical debate vivified by the Renaissance humanists on Otium and Negotium, or on contemplative life and active life. Montaigne’ s position on the subject will be described through the reading of two chapters, which maintain - although distant in time - lively and instigating relationships among themselves: De la Solitude, from the first book of the Essais and De ménager sa volonté, from the third. We intend to show how the peculiar solitary’s ethos that Montaigne constitutes for itself by appropriation of the Senecan’ s lessons overcoming the traditional dichotomy to serving the affirmation of another notion of Prudentia and "act well” in public life. The fundamental nexus of this notion is not in the ambition of glory but in the possession of oneself or in the inner adequacy to the individual nature.O artigo examina a maneira particular como Montaigne se posiciona em defesa do otium no âmbito do debate clássico vivificado pelos humanistas da Renascença sobre otium e negotium, ou entre vida contemplativa e vida ativa, através da leitura de dois capítulos, que, embora distanciados no tempo, mantêm relações vivas e instigantes entre si: De la Solitude, do primeiro livro dos Essais e De ménager sa volonté, do terceiro. Na articulação entre os dois textos pretende-se mostrar como o ethos próprio à vida retirada que Montaigne constitui para si via apropriação das lições de Sêneca termina por superar a dicotomia tradicional servindo à afirmação de uma outra noção de prudentia e de “bem agir” na vida pública que tem seu nexo fundamental não na ambição de glória mas na posse de si ou na adequação interior à própria natureza.&nbsp

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure &lt;= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt

Discutindo a educação ambiental no cotidiano escolar: desenvolvimento de projetos na escola formação inicial e continuada de professores

A presente pesquisa buscou discutir como a Educação Ambiental (EA) vem sendo trabalhada, no Ensino Fundamental e como os docentes desta escola compreendem e vem inserindo a EA no cotidiano escolar., em uma escola estadual do município de Tangará da Serra/MT, Brasil. Para tanto, realizou-se entrevistas com os professores que fazem parte de um projeto interdisciplinar de EA na escola pesquisada. Verificou-se que o projeto da escola não vem conseguindo alcançar os objetivos propostos por: desconhecimento do mesmo, pelos professores; formação deficiente dos professores, não entendimento da EA como processo de ensino-aprendizagem, falta de recursos didáticos, planejamento inadequado das atividades. A partir dessa constatação, procurou-se debater a impossibilidade de tratar do tema fora do trabalho interdisciplinar, bem como, e principalmente, a importância de um estudo mais aprofundado de EA, vinculando teoria e prática, tanto na formação docente, como em projetos escolares, a fim de fugir do tradicional vínculo “EA e ecologia, lixo e horta”.Facultad de Humanidades y Ciencias de la Educació

[pt] UMA LEITURA DE DA GLÓRIA E DA PRESUNÇÃO E A IDÉIA DO AUTORETRATO NOS ENSAIOS DE MONTAIGNE

Na primeira página dos Ensaios Montaigne se dirigia diretamente aos seus leitores para declarar seu objetivo de representar a si mesmo em sua forma mais simples e ordinária. O intento do autoretrato o levava a advertir de imediato: je me suis proposée aucune fin que domestique et privée. Je n ay nulle consideration de ton service ny de ma gloire. Seu estilo privado, assim, representava uma novidade em seu tempo, contrastando com a prática geral dos autores humanistas de exibir sua erudição e servir à instrução pública a fim de fazer-se imortalizar como exemplos de sabedoria. Pretendemos investigar aqui esse caráter de novidade da obra de Montaigne sob a égide das motivações e dos procedimentos próprios do autoretrato tomando como centro de nosso estudo sua crítica da glória. Esta, com efeito, marcava sua distância em relação ao ideário humanista, assim como aos modos que determinavam os padrões da relação entre autor e leitor no Renascimento, pautados no desejo do autor de instruir e de glorificar-se e na disposição do leitor em ser instruído e elogiar. Para isso tomaremos aqui como objeto de análise o percurso da reflexão de Montaigne do ensaio Da glória, em que melhor desenvolve sua perspectiva negativa sobre as ambições e Da presunção, que se lhe segue imediatamente, em que toma a si mesmo como objeto, traçando de si um autoretrato oposto à aspiração de engrandecer-se.In the first page of his Essays, Montaigne turned directly to his readers to declare his purpose of representing himself in his most simple and ordinary way. The purpose of the autoportrait leads him to admonish: je me suis proposée aucune fin que domestique et privée. Je n ay nulle consideration de ton service ny de ma gloire. His private style represents a newness in that time, forming a contrast with the general practice of humanist authors of exhibits their erudiction, serving the public instruction and make himself imortals, occupying the position of wisdon models. Our intent here is investigate that newness character of Montaignes gloria theme. That critic marks his distance of the humanists ideals and of the modes which regulates the traditional patterns of relationship between author and reader in the Renaissance, founded in the author desire of instruct and glorify himself and in the disposition of the reader to learn and eulogize the author. To accomplishe our purpose, we anlyze here the course of Montaignes reflection in De la gloire, where his negative perspective of the ambitions takes the most expressive form, and De la praesumption, which follows De la gloire, with a autoportrait for theme, against the ambition of aggrandize himself

Immunocompromised patients with acute respiratory distress syndrome : Secondary analysis of the LUNG SAFE database

The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p < 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p < 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013

Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database

Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p &lt; 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p &lt; 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013

NEOTROPICAL ALIEN MAMMALS: a data set of occurrence and abundance of alien mammals in the Neotropics

Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or involuntarily introduced by humans into the Neotropics. Our data set is composed of 73,738 historical and current georeferenced records on alien mammal species of which around 96% correspond to occurrence data on 77 species belonging to eight orders and 26 families. Data cover 26 continental countries in the Neotropics, ranging from Mexico and its frontier regions (southern Florida and coastal-central Florida in the southeast United States) to Argentina, Paraguay, Chile, and Uruguay, and the 13 countries of Caribbean islands. Our data set also includes neotropical species (e.g., Callithrix sp., Myocastor coypus, Nasua nasua) considered alien in particular areas of Neotropics. The most numerous species in terms of records are from Bos sp. (n = 37,782), Sus scrofa (n = 6,730), and Canis familiaris (n = 10,084); 17 species were represented by only one record (e.g., Syncerus caffer, Cervus timorensis, Cervus unicolor, Canis latrans). Primates have the highest number of species in the data set (n = 20 species), partly because of uncertainties regarding taxonomic identification of the genera Callithrix, which includes the species Callithrix aurita, Callithrix flaviceps, Callithrix geoffroyi, Callithrix jacchus, Callithrix kuhlii, Callithrix penicillata, and their hybrids. This unique data set will be a valuable source of information on invasion risk assessments, biodiversity redistribution and conservation-related research. There are no copyright restrictions. Please cite this data paper when using the data in publications. We also request that researchers and teachers inform us on how they are using the data