15 research outputs found
Experimental Animal Models in Periodontology: A Review
In periodontal research, animal studies are complementary to in vitro experiments prior to testing new treatments. Animal models should make possible the validation of hypotheses and prove the safety and efficacy of new regenerating approaches using biomaterials, growth factors or stem cells. A review of the literature was carried out by using electronic databases (PubMed, ISI Web of Science). Numerous animal models in different species such as rats, hamsters, rabbits, ferrets, canines and primates have been used for modeling human periodontal diseases and treatments. However, both the anatomy and physiopathology of animals are different from those of humans, making difficult the evaluation of new therapies. Experimental models have been developed in order to reproduce major periodontal diseases (gingivitis, periodontitis), their pathogenesis and to investigate new surgical techniques. The aim of this review is to define the most pertinent animal models for periodontal research depending on the hypothesis and expected results
Cadaveric Evaluation of Load to Failure in Canine Gingiva Apposed With Varied Suture Patterns Using Poliglecaprone 25
Protease repertoires of cells adherent to membranes recovered after guided tissue regeneration
The Effect of Platelet-Derived Growth Factor on the Cellular Response of the Periodontium: An Autoradiographic Study on Dogs
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142150/1/jper0429.pd