Suppression of inflammation during adipogenic differentiation in human preadipocytes

INTRODUCTION: Preadipocytes are present in adipose tissues throughout adult life that can differentiate into mature adipocytes in response to environmental factors. However, little is known about the secretory inflammation-associated cytokines / chemokines during adipogenic differentiation. METHODS: Human preadipocytes-subcutaneous (HPA-s) cells were cultured to 80% confluence. From preadipocytes to mature adipocytes, a total of six induction cycles …published_or_final_versio

Cellular mechanisms involved in intermittent hypoxia-induced heart damage in rat

Poster PresentationBACKGROUND: Obstructive sleep apnoea (OSA), characterised by intermittent hypoxia (IH) during sleep, is increasingly recognised as an independent risk factor of cardiovascular diseases (CVD). OSA has been reported to be associated with changes in the levels of circulating oxidative stress and inflammatory markers as well as dyslipidemia, supporting their mediating roles in cardiovascular pathogenesis. This study aimed to investigate the ...published_or_final_versionThe 17th Medical Research Conference, Department of Medicine, The University of Hong Kong, Hong Kong, 14 January 2012. In Hong Kong Medical Journal, 2012, v. 18 n. 1, suppl. 1, p. 23, abstract no. 2

n-Type doped transparent conducting binary oxides: an overview

This article focuses on n-type doped transparent conducting binary oxides – namely, those with the general formula MxOy:D, where MxOy is the host oxide material and D is the dopant element. Such materials are of great industrial importance in modern materials chemistry. In particular, there is a focus on the search for alternatives to indium-based materials, prompted by indium's problematic supply risk as well as a number of functional factors. The important relationship between computational study and experimental observation is explored, and an extensive comparison is made between the electrical properties of a number of the most interesting experimentally-prepared materials. In writing this article, we aim to provide both an accessible tutorial of the physical descriptions of transparent conducting oxides, and an up-to-date overview of the field, with a brief history, some key accomplishments from the past few decades, the current state of the field as well as postulation on some likely future developments

A new fast sub-optimal search method for closed-loop transmit diversity system with limited number of feedback bits

IEEE Radio and Wireless Conference, Atlanta, Georgia, USA, 19-22 September 2004In this paper, we present a fast sub-optimal searching algorithm for the closed-loop transmit diversity scheme used in wireless system. Under the low mobility condition and with perfect channel knowledge at the receiving end, our proposed searching algorithm can use a limited number of feedback bits to provide a sub-optimal solution that can achieve the SNR values close to the optimal solution with a greatly reduced complexity and outperform other sub-optimal schemes. The scheme also works well under the presence of feedback errors. © 2004 IEEE.published_or_final_versio

Novel search algorithm for closed-loop transmit diversity system with limited number of feedback bits

We propose two simple closed-loop transmit diversity schemes with a fixed number of feedback bits being allocated for each transmit antenna. Under a low mobility condition and with perfect channel knowledge at the receiver, we show that our proposed schemes can achieve signal-to-noise ratio (SNR) values close to the optimal solution but with greatly reduced complexity. We also show that our methods outperform other suboptimal schemes such as the co-phasing method. © 2004 IEEE.published_or_final_versionIEEE 60th Vehicular Technology Conference 2004-Fall (VTC2004-Fall), "Wireless Technologies for Global Security", Los Angeles, CA, USA, 26-29 September 2004. In IEEE - VTS Vehicular Technology Conference Proceedings, 2004, v. 60 n. 3, p. 1849-185

Modification of serum adiponectin and CINC-1 levels by intermittent hypoxia and/or hyperlipidemia in vivo

published_or_final_versionThe 15th Medical Research Conference, Department of Medicine, The University of Hong Kong, Hong Kong, 16 January 2010. In Hong Kong Medical Journal, 2010, v. 16, suppl. 1, p. 22, abstract no. 2

Age-dependent alterations of cigarette smoke-induced oxidative and inflammatory responses in rats

Oral PresentationBACKGROUND: Cigarette smoking (CS) is a leading cause of chronic obstructive pulmonary disease (COPD). The prevalence of COPD is much higher among the elderly. However, the impact of early-age CS exposure on CS induced COPD is unknown. This study aimed to investigate whether CS-induced oxidative and inflammatory responses were ...published_or_final_versionThe 17th Medical Research Conference, Department of Medicine, The University of Hong Kong, Hong Kong, 14 January 2012. In Hong Kong Medical Journal, 2012, v. 18 n. 1, suppl. 1, p. 39, abstract no. 5

Role of heme oxygenase-1 in intermittent hypoxia-induced inflammation and oxidative stress in eAhy 926 endothelial cell line

published_or_final_versionThe 16th Medical Research Conference (MRC), Department of Medicine, The University of Hong Kong, Hong Kong, China, 22 January 2011. In Hong Kong Medical Journal, 2011, v. 17 n. 1, suppl. 1, p. 29, abstract no. 4

(-)-Epigallocatechin-3-gallate Reduces Cigarette Smoke-Induced Airway Neutrophilic Inflammation and Mucin Hypersecretion in Rats

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