6 research outputs found
The KB paradigm and its application to interactive configuration
The knowledge base paradigm aims to express domain knowledge in a rich formal
language, and to use this domain knowledge as a knowledge base to solve various
problems and tasks that arise in the domain by applying multiple forms of
inference. As such, the paradigm applies a strict separation of concerns
between information and problem solving. In this paper, we analyze the
principles and feasibility of the knowledge base paradigm in the context of an
important class of applications: interactive configuration problems. In
interactive configuration problems, a configuration of interrelated objects
under constraints is searched, where the system assists the user in reaching an
intended configuration. It is widely recognized in industry that good software
solutions for these problems are very difficult to develop. We investigate such
problems from the perspective of the KB paradigm. We show that multiple
functionalities in this domain can be achieved by applying different forms of
logical inferences on a formal specification of the configuration domain. We
report on a proof of concept of this approach in a real-life application with a
banking company. To appear in Theory and Practice of Logic Programming (TPLP).Comment: To appear in Theory and Practice of Logic Programming (TPLP
Common surgical procedures in pilonidal sinus disease: A meta-analysis, merged data analysis, and comprehensive study on recurrence
Abstract We systematically searched available databases. We reviewed 6,143 studies published from 1833 to 2017. Reports in English, French, German, Italian, and Spanish were considered, as were publications in other languages if definitive treatment and recurrence at specific follow-up times were described in an English abstract. We assessed data in the manner of a meta-analysis of RCTs; further we assessed non-RCTs in the manner of a merged data analysis. In the RCT analysis including 11,730 patients, Limberg & Dufourmentel operations were associated with low recurrence of 0.6% (95%CI 0.3–0.9%) 12 months and 1.8% (95%CI 1.1–2.4%) respectively 24 months postoperatively. Analysing 89,583 patients from RCTs and non-RCTs, the Karydakis & Bascom approaches were associated with recurrence of only 0.2% (95%CI 0.1–0.3%) 12 months and 0.6% (95%CI 0.5–0.8%) 24 months postoperatively. Primary midline closure exhibited long-term recurrence up to 67.9% (95%CI 53.3–82.4%) 240 months post-surgery. For most procedures, only a few RCTs without long term follow up data exist, but substitute data from numerous non-RCTs are available. Recurrence in PSD is highly dependent on surgical procedure and by follow-up time; both must be considered when drawing conclusions regarding the efficacy of a procedure