748 research outputs found

    Morphology and structure of the 1999 lava flows at Mount Cameroon Volcano (West Africa) and their bearings on the emplacement dynamics of volume-limited flows

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    The morphology and structure of the 1999 lava flows at Mount Cameroon volcano are documented and discussed in relation to local and source dynamics. Structures are analysed qualitatively and more detailed arguments are developed on the processes of levee formation and systematic links between flow dynamics and levee-channel interface geometry. The flows have clear channels bordered by four main types of levees: initial, accretionary, rubble and overflow levees. Thermally immature pahoehoe lava units with overflow drapes define the proximal zone, whereas rubble and accretionary levees are common in the distal region bordering thermally mature aa clinker or blocky aa flow channels. Pressure ridges, squeeze-ups and pahoehoe ropes are the prevalent compressive structures. Standlines displayed on clinkery breccias are interpreted to represent levee-channel interactions in response to changing flow levels. These data complement previous knowledge on lava flow morphology, thus far dominated by Etnean and Hawaiian examples

    Aberrant Motility in Unaffected Small Bowel is Linked to Inflammatory Burden and Patient Symptoms in Crohn's Disease.

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    BACKGROUND: Inflammation-related enteric dysmotility has been postulated as a cause for abdominal symptoms in Crohn's disease (CD). We investigated the relationship between magnetic resonance imaging-quantified small bowel (SB) motility, inflammatory activity, and patient symptom burden. METHODS: The Harvey-Bradshaw index (HBI) and fecal calprotectin were prospectively measured in 53 patients with CD (median age, 35; range, 18-78 years) the day before magnetic resonance enterography, which included a dynamic (cine), breath-hold motility sequence, repeated to encompass the whole SB volume. A validated registration-based motility quantitation technique produced motility maps, and regions of interest were drawn to include all morphologically normal SB (i.e., excluding diseased bowel). Global SB motility was correlated with calprotectin, HBI, and symptom components (well-being, pain, and diarrhea). Adjustment for age, sex, smoking, and surgical history was made using multivariate linear regression. RESULTS: Median calprotectin was 336 (range, 0-1280). Median HBI, motility mean, and motility variance were 3 (range, 0-16), 0.33 (0.18-0.51), and 0.01 (0.0014-0.034), respectively. Motility variance was significantly negatively correlated with calprotectin (rho = -0.33, P = 0.015), total HBI (rho = -0.45, P 0.05). CONCLUSIONS: Reduced motility variance in morphologically normal SB is associated with patient symptoms and fecal calprotectin levels, supporting the hypothesis that inflammation-related enteric dysmotility may explain refractory abdominal symptoms in CD

    Description des catĂ©gories de personnes contribuant Ă  l’affluence dans un service des urgences public urbain de la ville du Cap, en Afrique du Sud

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    CITATION: Ahiable, E., Lahri, S. & Bruijns, S. 2017. Describing the categories of people that contribute to an Emergency Centre crowd at Khayelitsha hospital, Western Cape, South Africa. African Journal of Emergency Medicine, 7(2):68–73. doi:10.1016/j.afjem.2017.01.001.The original publication is available at https://www.afjem.orgIntroduction: Emergency Centre (EC) crowding has globally been recognised to adversely affect patients, staff and visitors. Anecdotally, local ECs are perceived to be fairly crowded, however, not much is known about the size of this crowd and what constitutes it. Although more reliable, resource restrictions render more detailed flow studies less achievable. This study describes the EC crowd at Khayelitsha hospital in Cape Town, South Africa as the number and different categories of people, at predefined times during the day over a four-week period. Methods: A prospective, cross-sectional design was used. Headcounts were made by predefined groups at 09h00, 14h00, and 21h00 every day for four weeks. Predefined groups included doctors, nurses, visitors, patients, and other allied health staff. Summary statistics were used to describe the data. Precision was described using the 95% confidence interval. Results: A total of 16,353 people were counted during the study period. On average, 6370 (39%) of the groups were staff, 5231 (32%) were patients and 4752 (29%) were visitors. Of the staff, 586 (3.6%) were EC doctors, 733 (4.4%) were non-EC doctors, 1488 (9%) were EC nurses, and 445 (3%) were non-EC nurses. Although patient numbers in the EC remained constant, visitors and non-EC staff varied significantly with visitors peaking in the afternoon and non-EC staff drastically reducing in the evening. The EC was consistently crowded – average occupancy: 130%. Conclusion: Staff levels fluctuated predictably, reducing at night and over weekends, while patient levels remained constant. Non-EC doctors more than doubled during the day on week shifts, in significantly more numbers thanEC doctors, suggesting thatmany of the patients in the ECwere likely to be admissions boarding in the EC. Visitor numbers were substantial during visiting hours and further aggravated crowding. Resourcelight studies involving flow are important to explore crowding in low- and middle income settings.Introduction: La foule prĂ©sente dans les Services des urgences (SU) a Ă©tĂ© globalement reconnue comme affectant nĂ©gativement les patients, les employĂ©s et les visiteurs. Nous savons que les SU locaux sont perçus comme relativement bondĂ©s, cependant, peu d’informations sont disponibles sur l’ampleur de cette affluence et les personnes qui la composent. Les Ă©tudes de flux plus dĂ©taillĂ©es, bien que plus fiables, sont rendues plus difficiles par les restrictions de ressources. Cette Ă©tude dĂ©crit l’affluence au SU de l’hĂŽpital de Khayelitsha selon le nombre et les diffĂ©rentes catĂ©gories de personnes qui s’y trouvent Ă  des horaires prĂ©dĂ©finis d’une journĂ©e, sur une pĂ©riode de quatre semaines. MĂ©thodes: Une Ă©tude transversale et prospective a Ă©tĂ© utilisĂ©e. Le dĂ©nombrement a Ă©tĂ© rĂ©alisĂ© selon des groupes prĂ©dĂ©finis Ă  09h00, 14h00 et 21h00 tous les jours pendant quatre semaines. Les groupes prĂ©dĂ©finis Ă©taient constituĂ©s des mĂ©decins, infirmiĂšres, visiteurs, patients et autre personnel mĂ©dical affiliĂ©. Des statistiques sommaires ont Ă©tĂ© utilisĂ©es pour dĂ©crire les donnĂ©es. La prĂ©cision a Ă©tĂ© dĂ©crite en utilisant un intervalle de confiance de 95%. RĂ©sultats: au total, 16,353 personnes ont Ă©tĂ© comptabilisĂ©es au cours de la pĂ©riode couverte par l’étude. En moyenne, 6370 (39%) personnes Ă©taient des employĂ©s, 5231 (32%) Ă©taient des patients et 4752 (29%) Ă©taient des visiteurs. Parmi les employĂ©s, 586 (3,6%) Ă©taient des mĂ©decins du SU, 733 (4,4%) Ă©taient des mĂ©decins n’appartenant pas au SU, 1488 (9%) Ă©taient des infirmiĂšres du SU et 445 (3%) Ă©taient des infirmiĂšres n’appartenant pas au SU. Bien que le nombre de patients au SU reste constant, les visiteurs et employĂ©s hors SU variaient dans une large mesure, le nombre de visiteurs connaissant un pic dans l’aprĂšs-midi et le nombre d’employĂ©s n’appartenant pas au SU diminuant considĂ©rablement le soir. Le SU Ă©tait bondĂ© en permanence, avec un taux d’occupation moyen de 130%. Discussion: Les niveaux d’employĂ©s fluctuaient de maniĂšre prĂ©visible, se rĂ©duisant la nuit et les weekends, alors que les niveaux de patients restaient constants. Le nombre de mĂ©decins n’appartenant pas au SU faisait plus que doubler pendant la journĂ©e sur les quarts de la semaine, de maniĂšre beaucoup plus significative que le nombre de mĂ©decins du SU, suggĂ©rant que nombre des patients se prĂ©sentant au SU Ă©taient susceptibles d’ĂȘtre admis. Le nombre de visiteurs Ă©tait substantiel pendant les heures de visite et venait encore agraver l’affluence. Des Ă©tudes n’impliquant que peu de ressources sont importantes pour Ă©tudier l’affluence dans des pays Ă  faibles et moyens revenus.Publishers versio

    Education can improve the negative perception of a threatened long-lived scavenging bird, the Andean condor

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    Human-wildlife conflicts currently represent one of the main conservation problems for wildlife species around the world. Vultures have serious conservation concerns, many of which are related to people's adverse perception about them due to the belief that they prey on livestock. Our aim was to assess local perception and the factors influencing people's perception of the largest scavenging bird in South America, the Andean condor. For this, we interviewed 112 people from Valle FĂ©rtil, San Juan province, a rural area of central west Argentina. Overall, people in the area mostly have an elementary education, and their most important activity is livestock rearing. The results showed that, in general, most people perceive the Andean condor as an injurious species and, in fact, some people recognize that they still kill condors. We identified two major factors that affect this perception, the education level of villagers and their relationship with livestock ranching. Our study suggests that conservation of condors and other similar scavengers depends on education programs designed to change the negative perception people have about them. Such programs should be particularly focused on ranchers since they are the ones who have the worst perception of these scavengers. We suggest that highlighting the central ecological role of scavengers and recovering their cultural value would be fundamental to reverse their persecution and their negative perception by people.Fil: Cailly Arnulphi, VerĂłnica BeatrĂ­z. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas FĂ­sicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Lambertucci, Sergio Agustin. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; ArgentinaFil: Borghi, Carlos Eduardo. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas FĂ­sicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; Argentin

    SWAMI: A SWARM-INTELLIGENT OPTIMIZATION TECHNIQUE FOR VOLTAGE COLLAPSE MITIGATION

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    In this paper, a voltage collapse optimization system based on comparative studies of swarm-intelligent techniques is proposed for voltage collapse mitigation in power system network. The approach draws inspiration from the idea of utilizing the intelligent behavior of swarm-based artificial machine intelligence technique coined SWAMI for voltage collapse minimization or prevention through dynamic shunt compensation of overloaded power network buses. Several simulation studies have been conducted considering three very popular and successful SWAMI agents – the PSOM, BCOM and ACOM on an IEEE benchmark power network with promising results. Simulation studies showed that the PSOM SWAMI exhibited the most stable response in terms of voltage profile collapse and recovery from voltage collapse state after voltage sensitivity studies. Safe margins of loading and optimal shunt compensations are determined based on the SWAMI techniques

    HIV-1 subtype A infection in a community of intravenous drug users in Pakistan

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    BACKGROUND: Data on the subtypes of HIV in a population help in predicting the potential foci of epidemic, tracking the routes of infection and following the patterns of the virus' genetic divergence. Globally, the most prevalent HIV infection is the HIV-1 subtype C. In Asia, predominant subtypes of HIV-1 are B, C, and CRF-01AE. During the last few years, HIV prevalence in Pakistan has taken the form of a concentrated epidemic in at least two high risk groups, namely, Intravenous Drug Users (IDUs) and Male Sex Workers (MSWs). Factors that have facilitated the proliferation of HIV infection include transmission through a large number of repatriates and needle-sharing intravenous drug users, unscreened blood transfusions, and sexual illiteracy. The HIV subtypes infecting Pakistani populations have not been explored to date. In this study, we analyzed HIV-1 subtypes from in a high-risk community of IDUs in Karachi, the largest city of Pakistan. METHODS: Samples were collected from 34 IDUs after their informed consent. In addition, the study subjects were administered a questionnaire regarding their sexual behavior and travel history. For HIV analysis, DNA was extracted from the samples and analyzed for HIV types and subtypes using subtype-specific primers in a nested polymerase chain reaction (PCR). The results from this PCR were further confirmed using the Heteroduplex Mobility Assay (HMA). RESULTS: We found HIV-1 subtype A in all the 34 samples analyzed. A few of the study subjects were found to have a history of travel and stay in the United Arab Emirates. The same subjects also admitted to having contact with commercial sex workers during their stay abroad. CONCLUSION: Our study therefore shows clade A HIV-1 to be prevalent among the IDUs in Karachi. As the prevalence of HIV in Pakistan continues to rise, more work needs to be done to track the infection, and to analyze the strains of HIV spreading through the country

    Cultural differences in postnatal quality of life among German-speaking women - a prospective survey in two countries.

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    Assessment of quality of life after childbirth is an important health-outcome measurement for new mothers and is of special interest in midwifery. The Mother-Generated Index (MGI) is a validated instrument to assess postnatal quality of life. The tool has not been applied for making a cross-cultural comparison before. This study investigated (a) responses to the MGI in German-speaking women in Germany and Switzerland; and (b) associations between MGI scores on the one hand and maternity and midwifery care on the other

    Parkinsonism caused by adverse drug reactions: a case series

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    <p>Abstract</p> <p>Introduction</p> <p>Parkinsonism puts a high direct cost burden on both patient and caregiver. Several reports of drug-induced parkinsonism have been published, but to the best of our knowledge, there has not been any report of quinine or halothane inducing parkinsonism.</p> <p>Case presentation</p> <p>We describe two cases of parkinsonism possibly caused by adverse drug reaction to quinine in a 29-year-old black Nigerian woman and to halothane in a 36-year-old black Hausa (Nigerian) man who received it as general anaesthesia for appendicectomy in our teaching hospital.</p> <p>Conclusion</p> <p>These are two unusual cases of parkinsonism caused by adverse drug reactions to high-dose quinine and to halothane as general anaesthesia. We consider that these two cases are important in bringing this potential side-effect to the attention of both pharmacologists and primary care physicians as these are two of the most commonly used medications in our clinics. We conclude that parkinsonism should be included among the adverse drug reactions to high-dose quinine and halothane general anaesthetic.</p

    Acceptability of Condom Promotion and Distribution Among 10-19 Year-Old Adolescents in Mpwapwa and Mbeya Rural Districts, Tanzania.

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    \ud The HIV/AIDS pandemic remains a leading challenge for global health. Although condoms are acknowledged for their key role on preventing HIV transmission, low and inappropriate use of condoms persists in Tanzania and elsewhere in Africa. This study assesses factors affecting acceptability of condom promotion and distribution among adolescents in Mpwapwa and Mbeya rural districts of Tanzania. Data were collected in 2011 as part of a larger cross-sectional survey on condom use among 10-19 year-olds in Mpwapwa and Mbeya rural districts of Tanzania using a structured questionnaire. Associations between acceptability of condom promotion and distribution and each of the explanatory variables were tested using Chi Square. Multivariate logistic regression model was used to examine independent predictors of the acceptability of condom promotion and distribution using STATA (11) statistical software at 5% significance level. Mean age of the 1,327 adolescent participants (50.5% being males) was 13.5 years (SD = 1.4). Acceptance of condom promotion and distribution was found among 37% (35% in Mpwapwa and 39% in Mbeya rural) of the adolescents. Being sexually active and aged 15-19 was the strongest predictor of the acceptability of condom promotion and distribution (OR = 7.78, 95% CI 4.65-12.99). Others were; not agreeing that a condom is effective in preventing transmissions of STIs including HIV (OR = 0.34, 95% CI 0.20-0.56), being a resident of Mbeya rural district (OR = 1.67, 95% CI 1.28-2.19), feeling comfortable being seen by parents/guardians holding/buying condoms (OR = 2.20, 95% CI 1.40-3.46) and living with a guardian (OR = 1.48, 95% CI 1.08-2.04). Acceptability of condom promotion and distribution among adolescents in Mpwapwa and Mbeya rural is low. Effect of sexual activity on the acceptability of condom promotion and distribution is age-dependent and was the strongest. Feeling comfortable being seen by parents/guardians buying or holding condoms, perceived ability of condoms to offer protection against HIV/AIDS infections, district of residence and living arrangements also offered significant predictive effect. Knowledge of these factors is vital in designing successful and sustainable condom promotion and distribution programs in Tanzania.\u

    Factors associated with persistent hypertension after puerperium among women with pre-eclampsia/eclampsia in Mulago hospital, Uganda

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    <p>Abstract</p> <p>Background</p> <p>Women with severe pre-eclampsia/eclampsia are at risk of developing chronic hypertension in future. Chronic hypertension may manifest initially as persistent hypertension at the end of the puerperium. The objective was to determine the incidence and maternal biochemical, hematological and socio-demographic risk factors for persistent hypertension in patients with pre-eclampsia/eclampsia.</p> <p>Methods</p> <p>This was a prospective cohort study conducted from November 2008 to May 2009 at Mulago hospital labor ward and postnatal clinic. Participants were 200 women managed for pre-eclampsia/eclampsia and followed up to the end of the puerperium. Data was collected through using pre-coded interviewer-administered questionnaires, checking medical records and laboratory investigations. STATA (release 9) software was used for data analysis. At bivariate analysis, the relative risk of persistent hypertension was estimated at the 95% confidence level. Using multivariate logistic regression analysis, factors that were independently associated with persistent hypertension were evaluated.</p> <p>Results</p> <p>Fifty four (27.7%) out of the total 195 women had persistent hypertension after puerperium. Serum creatinine and the age of the patient were the only factors associated with persistence of hypertension after puerperium.</p> <p>Conclusion</p> <p>Nearly every one in four mothers with pre-eclampsia/eclampsia are at risk of persistent hypertension after the puerperium. Serum creatinine, serum uric acid and participants' age were the only factors independently associated with persistence of hypertension after the puerperium.</p
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