Production of antibodies specific for human thymus derived lymphocytes purified from antibodies crossreacting with colony forming cells.

Antisera raised in rabbits against human thymocytes contain antibodies against peripheral lymphocytes of normal persons, patients with chronic lymphatic leukemia (CLL) and lymphoblastoid cell lines. Absorption of antithymocyte serum with CLL lymphocytes and spleen preserved the antibody activity against normal peripheral lymphocytes and a lymphoblastoid cell line of T cell type (MOLT 4), while eliminating antibodies reacting with CLL lymphocytes and a B cell type lymphoblastoid cell line (RPMI 1788). The incubation of human bone marrow cells with not absorbed anti thymocyte globulin reduced considerably the number of stem cells committed to granulopoietic differentiation (CFU C). No reduction of CFU C, however, was observed with specifically absorbed anti thymocyte globulin. The possible application of stem cell sparing, purified anti thymocyte globulin for the suppression of graft versus host reactions in human bone marrow transplantation is discussed

Counteractive self-control::When making temptation available makes temptation less tempting

We propose a self-control analysis of the role of availability in valuation. We explored the hypothesis that, when temptation becomes available, counteractive self-control processes render it less valuable. We found evidence for devaluation of available temptation among gym users before they choose to forgo an unhealthy snack rather than after they make their choice (Study 1), and among students evaluating leisure activities when their decision to enroll in an uninteresting class is reversible rather than irreversible (Study 2