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Not AvailableIn high yielding dairy cows, one of the major cause of lameness during transition period is the altered nutritional status of pregnant animal. Concentrations of essential nutrients get varied and often decrease around calving due to physiological factors and thus extra-supplementation is recommended in these animals. Blood measures are frequently used in assessment of the vital nutrients for predicting the risk of lameness during this period. The objective of this study was to investigate the nutritional status of healthy and lame Karan Fries (KF) cows and their association with lameness score during transition period. For this fifteen high-yielding crossbreed (KF) healthy cows and fifteen high yielding crossbreed (KF) lame cows were randomly selected from the Livestock Research Centre (LRC) of National Diary Research Institute, Karnal for pooled blood sample collection. Samples were collected 60d, 15d pre-partum, on the day of calving, and 60d, 15d post-partum. The results revealed that the mean plasma biotin, zinc (below critical level) and calcium (within range) levels were significantly lower (P<0.05) in lame KF cows while β-hydroxybutyrate (BHBA) concentrations was significantly higher, however no significant difference in plasma copper, glucose and non-esterified fatty acids (NEFA) concentrations was found in lame cows as compared to normal KF cows during this period. There was also significant (P<0.05) variation of blood biochemical profiles (glucose, NEFA and BHBA) and plasma biotin concentration among different lameness scores (1-5) whereas no relation of mineral profiles (calcium, zinc and copper) was seen with lameness score.Not Availabl

HIT-COVID, a global database tracking public health interventions to COVID-19

The COVID-19 pandemic has sparked unprecedented public health and social measures (PHSM) by national and local governments, including border restrictions, school closures, mandatory facemask use and stay at home orders. Quantifying the effectiveness of these interventions in reducing disease transmission is key to rational policy making in response to the current and future pandemics. In order to estimate the effectiveness of these interventions, detailed descriptions of their timelines, scale and scope are needed. The Health Intervention Tracking for COVID-19 (HIT-COVID) is a curated and standardized global database that catalogues the implementation and relaxation of COVID-19 related PHSM. With a team of over 200 volunteer contributors, we assembled policy timelines for a range of key PHSM aimed at reducing COVID-19 risk for the national and first administrative levels (e.g. provinces and states) globally, including details such as the degree of implementation and targeted populations. We continue to maintain and adapt this database to the changing COVID-19 landscape so it can serve as a resource for researchers and policymakers alike